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Trilosar 12.5 Tablet

Losartan (50mg)+ Amlodipine (5mg)+ Chlorthalidone (12.5mg)

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Trilosar 12.5 Tablet is a combination of medicines used to treat hypertension (high blood pressure) when a single medication is not effective. It helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Apr 2026 | 11:11 AM (IST)

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General Information

Contains

Losartan (50mg)+ Amlodipine (5mg)+ Chlorthalidone (12.5mg)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Trilosar 12.5 Tablet should be taken with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more, so it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it, even if you feel well. High blood pressure does not usually have symptoms, and if you stop taking it, your risk of heart attack or stroke may increase.

The most common side effects of this medicine include headache, dizziness, tiredness, and altered taste. Consult your doctor if any of these bother you, or get worse, or won't go away. If you experience ankle or foot swelling, to reduce it, raise your legs while you are sitting down. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, level of electrolytes, and blood sugar level checked regularly to make sure that this medicine is working properly.

Uses of Trilosar Tablet

Hypertension (high blood pressure)

Benefits of Trilosar Tablet

Hypertension (high blood pressure)
Trilosar 12.5 Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Trilosar Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trilosar

Ankle swelling
Headache
Dizziness
Tiredness
Palpitations
Sleepiness
Increased blood uric acid
Glucose intolerance
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Upset stomach
Altered blood lipid level

How to use Trilosar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trilosar 12.5 Tablet may be taken with or without food.

How Trilosar Tablet works

Trilosar 12.5 Tablet is a combination of three medicines: Losartan, Amlodipine and Chlorthalidone. Losartan is an angiotensin receptor blocker (ARB) and Amlodipine is a calcium channel blocker (CCB). They work by widening and relaxing the blood vessels, thereby lowering blood pressure. Chlorthalidone is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time it also works by relaxing blood vessels and improving blood flow.

Quick tips

You have been prescribed Trilosar 12.5 Tablet for the treatment of high blood pressure.
Lowering high blood pressure helps prevent strokes and heart attacks.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Trilosar 12.5 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness, or a very dry mouth.
Use of Trilosar 12.5 Tablet during pregnancy or breastfeeding is unsafe.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Trilosar 12.5 Tablet.

Pregnancy

UNSAFE

Trilosar 12.5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Trilosar 12.5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Trilosar 12.5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Trilosar 12.5 Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney

CAUTION

Trilosar 12.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Trilosar 12.5 Tablet is not recommended in these patients.

Liver

UNSAFE

Trilosar 12.5 Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Trilosar 12.5 Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

What is Trilosar 12.5 Tablet used for?

Trilosar 12.5 Tablet is used to manage high blood pressure (hypertension), helping prevent strokes, heart attacks, and kidney problems.

Who should avoid taking Trilosar 12.5 Tablet?

People should avoid taking Trilosar 12.5 Tablet if they are allergic to any ingredient present in it, have severe kidney or liver disease, or are pregnant or breastfeeding.

Can Trilosar 12.5 Tablet cause serious side effects?

Although they are rare, serious side effects of Trilosar 12.5 Tablet may include low blood pressure, kidney problems, electrolyte imbalances, or allergic reactions. Seek immediate medical help if severe symptoms occur.

Should I monitor my blood pressure regularly during Trilosar 12.5 Tablet treatment?

Yes, regular monitoring helps ensure Trilosar 12.5 Tablet is working effectively and safely.

Can I stop taking Trilosar 12.5 Tablet if my blood pressure reading drops to normal?

You should not stop taking Trilosar 12.5 Tablet suddenly, even if your blood pressure reading comes into the normal range, or you start feeling well. Stopping suddenly can make your blood pressure shoot up again or worsen. Always consult your doctor before making any changes in your treatment plan.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Trilosar 12.5 Tablet

Once A Day

92%

Twice A Day

What are you using Trilosar Tablet for?

Hypertension (high blood pressure)

100%

How much was the improvement?

Excellent

44%

Average

33%

Poor

22%

What were the side-effects while using Trilosar 12.5 Tablet?

No Side Effect

33%

Weight loss

33%

Sleepiness

33%

How do you take Trilosar Tablet?

With food

100%

Please rate Trilosar 12.5 Tablet on price

Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Trilosar 12.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Trilosar 12.5 Tablet

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Trilosar Tablet

Benefits of Trilosar Tablet

Side effects of Trilosar Tablet

How to use Trilosar Tablet

How Trilosar Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Trilosar 12.5 Tablet used for?

Who should avoid taking Trilosar 12.5 Tablet?

Can Trilosar 12.5 Tablet cause serious side effects?

Should I monitor my blood pressure regularly during Trilosar 12.5 Tablet treatment?

Can I stop taking Trilosar 12.5 Tablet if my blood pressure reading drops to normal?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Trilosar 12.5 Tablet

What are you using Trilosar Tablet for?

How much was the improvement?

What were the side-effects while using Trilosar 12.5 Tablet?

How do you take Trilosar Tablet?

Please rate Trilosar 12.5 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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