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Composition for TRIFEC

Clobetasol Topical(NA)

food interaction for TRIFEC

alcohol interaction for TRIFEC

pregnancy interaction for TRIFEC

lactation interaction for TRIFEC

It can be taken with or without food, but it is better to take Trifec cream at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Trifec cream may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Trifec cream is probably safe to use during breastfeeding. Please consult your doctor.


Clobetasol Topical(NA)


Trifec cream is used to treat itching, redness, dryness, inflammation, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).

How it works

Clobetasol belongs to a class of medications called as corticosteroids. It works by reducing the action of certain chemicals in the body that cause inflammation.

Common side effects

Application site irritation, Burning sensation, Itching


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Expert advice for TRIFEC

  • Do not use in conditions such as acne, fungal skin infections, e.g. athlete's foot, ringworm, candida skin infections, severe flushing of skin on and around your nose (rosacea), spotty red rash around your mouth (perioral dermatitis), infected skin (unless the infection is being treated with an anti-infective medicine at the same time),itchy skin around the genitals or back passage, itchy skin which is not inflamed, nappy rash, widespread plaque psoriasis (raised, red patches covered with a silvery white buildup of dead skin cells or scale).
  • Caution is to be observed while applying the cream on large areas of the body for a long time like few weeks or months.
  • If your skin problem does not improve in 2 to 4 weeks, talk to your doctor.
  • It should not take if patient is allergic to clobetasol propionate or any of its ingredients.
  • It sholud not given to children below 1 year of age.

Frequently asked questions for TRIFEC

Clobetasol Topical

Q. Is clobetasol propionate a steroid/ an antifungal/ OTC?
Clobetasol (also available as cosvate cream, cosvate G) is a potent topical corticosteroid used for the treatment of itching, redness, dryness, inflammation, and discomfort of various scalp and skin conditions. It is not an antifungal. It is available only by prescription given by your doctor. 
Q. Is clobetasol propionate topical used for hair loss/ does clobetasol help hair growth?
Clobetasol topical is used for discomfort in various scalp and skin conditions; however not used for treatment of hair loss or hair growth. Always consult your doctor regarding its use.
Q. Does clobetasol propionate topical cause hair loss / thinning of skin?
Long-term use of steroids may damage your hair or skin. Always follow the advice of your doctor regarding its use.
Q. Is clobetasol propionate topical good for acne/ athlete's foot/ ringworm?
Clobetasol topical should not be used for conditions like acne, athlete’s foot or ringworm. Always consult your doctor regarding its use.


Content on this page was last updated on 17 January, 2014, by Dr. Varun Gupta (MD Pharmacology)