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Clobetasol is used to treat itching, redness, dryness, swelling, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).

How it works

Clobetasol is a highly potent topical corticosteroid. It reduces the actions of chemicals in the body that cause inflammation.

Common side effects

Itchy bump, Application site irritation, Burning sensation, Itching


Expert advice

Always clean the skin before a fresh dressing is put on since the germs can cause infections under warm and moist conditions under dressings.
Make sure you wash your hands after use or wear disposable plastic gloves while applying the cream on someone. Cream should be used on skin externally only.
Treatment beyond 2- 4 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week.
If your skin problem does not improve in 2 to 4 weeks, talk to your doctor. Do not use in conditions such as
  • Acne
  • Fungal skin infections, eg. athlete's foot, ringworm, candida skin infections.
  • Severe flushing of skin on and around your nose (rosacea).
  • Spotty red rash around your mouth (perioral dermatitis).
  • Infected skin (unless the infection is being treated with an anti-infective medicine at the same time).
  • Itchy skin around the genitals or back passage.
  • Itchy skin which is not inflamed.
  • Nappy rash
  • Widespread plaque psoriasis.

Frequently asked questions


Q. Is clobetasol propionate a steroid/ an antifungal/ OTC?
Clobetasol (also available as Cosvate cream, Cosvate G) is a potent topical corticosteroid used for the treatment of itching, redness, dryness, inflammation, and discomfort of various scalp and skin conditions. It is not an antifungal. It is available only by prescription given by your doctor.
Q. Is clobetasol propionate used for hair loss/ does clobetasol help hair growth?
Clobetasol is used for discomfort in various scalp and skin conditions; however not used for treatment of hair loss or hair growth. Always consult your doctor regarding its use.
Q. Does clobetasol propionate cause hair loss / thinning of skin?
Long-term use of steroids may damage your hair or skin. Always follow the advice of your doctor regarding its use.
Q. Is clobetasol propionate good for acne/ athlete's foot/ ringworm?
Clobetasol should not be used for conditions like acne, athlete’s foot or ringworm. Always consult your doctor regarding its use.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)