




Tresiba 100IU/ml Flextouch
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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Product introduction
Tresiba 100IU/ml Flextouch can be prescribed by itself or along with a fast-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the most benefit. It is usually taken once daily at the same time every day. However, on occasions when administration at the same time of the day is not possible, it may be taken at a different time of the day. Always ensure that there is a minimum gap of 8 hours between doses. If you stop taking it your blood sugar levels may rise very high and put you at risk of serious complications. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine is low blood sugar levels (hypoglycemia). To prevent hypoglycemia, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include injection site reactions like redness, swelling, or hard lumps (lipohypertrophy). Some people may also gain weight while taking insulin.
Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor before using it.
Uses of Tresiba Solution for Injection
Benefits of Tresiba Solution for Injection
Tresiba 100IU/ml Flextouch is a long-acting insulin that provides effective blood sugar control for people with diabetes. Its ultra-long duration of action allows for more flexibility in dosing times and ensures stable insulin levels over 24 hours or more. This helps reduce the risk of blood sugar fluctuations, particularly low blood sugar episodes (hypoglycemia), especially overnight. It offers the convenience of once-daily dosing and can be adjusted to fit individual needs, making it a valuable option for those managing both Type 1 and Type 2 diabetes.
Side effects of Tresiba Solution for Injection
- Auto-antibody formation
- Headache
- Injection site reactions (pain, swelling, redness)
- Severe hypoglycemia
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Upper respiratory tract infection
How to use Tresiba Solution for Injection
How Tresiba Solution for Injection works
Quick tips
- This medicine is injected under the skin. It needs to be injected once daily, at the same time every day.
- Injection below the skin of the abdomen results in faster absorption than other injection sites.
- Injection sites must be rotated to prevent hard lumps from developing at one site.
- Do not use it if the preparation is no longer clear and colorless or if it contains particles.
- Hypoglycemia (low blood sugar level) is a common side effect. Always carry some sugary food or fruit juice with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, and anxiety.
- Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Safety advice

Alcohol

Pregnancy
While on treatment with Tresiba 100IU/ml Flextouch, blood glucose monitoring is recommended and dose adjustment may be done on individual basis.

Breast feeding

Driving

Kidney
Frequent and regular monitoring of blood glucose levels is advised.

Liver
Frequent and regular monitoring of blood glucose levels is advised.
Frequently asked questions
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References
- Insulin degludec injection [Prescribing Information]. Bagsvaerd, Denmark: Novo Nordisk A/S; 2016. [Accessed 17 Oct. 2017] (online) Available from:
- Tresiba [Summary of Product Characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; 2017. [Accessed 08 Oct. 2021] (online) Available from:
- Insulin Degludec [Product Monograph]. Ontario, Canada: Novo Nordisk Canada Inc; 2019. [Accessed 08 Oct. 2021] (online) Available from:
- Zinman B, Philis-Tsimikas A, Cariou B, et al. Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: A 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care. 2012;35(12):2464-71. [Accessed 08 Oct. 2021] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
- Insulin degludec [Summary of Product Characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; 2017. [Accessed 05 Jul. 2023]. (online) Available from:




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