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Insulin Degludec

INFORMATION

Uses

Insulin Degludec is used in the treatment of type 1 diabetes and type 2 diabetes.

How it works

Insulin Degludec replaces the insulin that the body would normally make. Insulin is critical for promoting the use and storage of all the major nutrients : glucose, fats and proteins.

Common side effects

Application site itching, Bone-marrow suppression, Increase in body weight, Injection site pain, Injection site redness, Injection site swelling

AVAILABLE MEDICINE

Expert advice

  • Stop using insulin degludec if you experience any allergic reactions such as redness, swelling, rash and itching at the injection site, rash, itching or hives on the skin, wheezing or difficulty breathing, swelling of the face, lips, tongue or other parts of the body
  • Do not use insulin degludec if you are experiencing low blood sugar levels (hypoglycemia) as seen by symptoms such as cold sweat; cool pale skin, headache, rapid heartbeat, feeling sick, feeling very hungry, temporary changes in vision, drowsiness, unusual tiredness and weakness; nervousness or tremor, feeling anxious, feeling confused, difficulty in concentrating.Avoid using insulin degludec if you are pregnant or plan to become pregnant; breast-feeding
  • Do not take insulin degludec if you are suffering from kidney or liver problems; ever had nerve damage caused by your diabetes
  • Avoid drinking alcohol while taking insulin degludec
  • Take special precaution while taking insulin degludec if you do not eat regular meals, or you exercise a lot; or if you are feeling weak or ill.
  • Insulin degludec preparations are meant to be injected under the layer of skin. Do not inject it into a vein or a muscle. The angle of injection is critical; consult your doctor before first use to learn the injection technique.
  • Insulin degludec preparation must not be injected intravenously or intramuscularly. They should not be used in infusion pumps.
  • Injection sites must be rotated between upper arm (deltoid), abdominal, buttocks and thigh area from one injection to the next, such that each site of prick is used not more than once in 1 to 2 weeks; this is to reduce the skin changes at injection site.
  • Do not use if insulin degludec preparations is no longer clear and colorless or if it contains particles
  • Hypoglycemia may occur if the insulin dose is too high in relation to the insulin requirement. Always check your blood sugar levels at regular intervals
  • If you experience any symptoms of hypoglycemia (such as cold sweat; cool pale skin, headache, rapid heartbeat, feeling sick, feeling very hungry, temporary changes in vision, drowsiness, unusual tiredness and weakness; nervousness or tremor, feeling anxious, feeling confused, difficulty in concentrating) you need to raise your blood sugar immediately by eating sugars or carbohydrates.
  • Precaution must be taken while driving or handling machines as your ability to concentrate or react may be reduced if you suffer from low/high blood sugar levels or you have problems with your sight.

Frequently asked questions

Insulin Degludec

Q.What is insulin degludec?
Insulin degludec is long-acting basal insulin

Q.How does insulin degludec work?
Insulin degludec binds (attaches) to the human insulin receptor and performs effects actions same as human insulin. It promotes the uptake and utilization of sugar (glucose) in the body. It also stops the liver from producing more sugar. After the injection of insulin degludec multi-hexamers of insulin degludec are formed which act as store house (depots) from which small amounts of insulin degludec are continuously.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)