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    Insulin Degludec

    Information about Insulin Degludec

    Insulin degludec uses

    Insulin Degludec is used in the treatment of diabetes mellitus (Type 1 & Type 2).

    How insulin degludec works

    Insulin Degludec is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.

    Common side effects of insulin degludec

    Hypoglycemia (low blood sugar level), Injection site allergic reaction
    Content Details
    Written By
    Dr. Betina Chandolia
    MDS, BDS
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    05 Nov 2019 | 06:29 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Insulin Degludec

    • ₹1440 to ₹1942
      Novo Nordisk India Pvt Ltd
      2 variant(s)

    Expert advice for Insulin Degludec

    • This medicine is injected under the skin. It needs to be injected once daily, at the same time every day.
    • Injection below the skin of the abdomen results in faster absorption than other injection sites.
    • Injection sites must be rotated to prevent hard lumps from developing at one site.
    • Do not use if the preparation is no longer clear and colorless, or if it contains particles.
    • Hypoglycemia (low blood sugar level) is a common side-effect. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
    • Opened vials/cartridge stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).

    Frequently asked questions for Insulin Degludec

    Insulin Degludec

    Q. Is insulin glargine and Insulin Degludec the same?

    Both are man-made human insulin, but they are different. On one hand, insulin glargine is a long-acting insulin which cannot be combined with any other insulin. And on the other hand, Insulin Degludec is an ultra long-acting insulin which can be combined with other insulins (e.g., insulin apart).

    Q. What is Insulin Degludec?

    Insulin Degludec is a long-acting insulin used to control high blood sugar in adults and children as young as 1 year of age with diabetes. Insulin Degludec works like the body’s insulin that is normally produced by the body and helps move sugar from the blood into other body tissues where it is used for energy. Also, it stops the liver from producing more sugar.

    Q. Is Insulin Degludec better than Insulin Detemir?

    Both Insulin Degludec and Detemir are long-acting insulins with almost similar efficacy and safety. The only difference is that Insulin Degludec has the longest duration of action (more than 40 hours). The levels of this drug in the blood have minimum fluctuations throughout this duration.

    Q. Can Insulin Degludec cause weight gain?

    Yes, Insulin Degludec may cause weight gain in some patients. This may be due to the anabolic effect of insulin that promotes storage of glucose and fat.

    Q. Can Insulin Degludec raise your blood sugar?

    No, Insulin Degludec by itself does not raise blood sugar. However, inadequate dosing and/or discontinuation of treatment in patients requiring insulin may lead to high blood sugar. Furthermore, if the person has other illnesses along with diabetes, especially infections, then it may lead to high blood sugar levels. This may further increase the requirement of insulin.

    Q. Do I have to take Insulin Degludec at the same time every day?

    Yes, take Insulin Degludec preferably at the same time every day and exactly as advised by your doctor. On occasions when it is not possible to take it at the same time of the day, it can be taken at a different time of day. Make sure to have a minimum gap of 8 hours between doses. However, children and young adults must take their dose at the same time every day.

    Q. Can Insulin Degludec be used in combination with other diabetes drugs?

    Insulin Degludec can be used in combination with diabetes pills or fast-acting insulins. However, taking thiazolidinediones (TZDs) with Insulin Degludec may cause heart failure in some people. This can happen even if you have never had heart failure or heart problems. In case you already have heart failure, it may get worse on taking TZDs with Insulin Degludec.

    Q. What should I avoid while taking Insulin Degludec?

    Do not drive or operate heavy machinery until you know how Insulin Degludec affects you. Do not drink alcohol. Also, avoid taking any prescription or over-the-counter medicines that contain alcohol.

    Q. How do I take Insulin Degludec?

    Your health care provider will tell you how to take Insulin Degludec based on your individual needs. Usually, Insulin Degludec is taken by injection once daily. If you think your insulin dose needs adjustment because of illness, new medicine, stress, change in diet, or change in activity level, make sure to talk to your doctor.

    Content on this page was last updated on 05 November, 2019, by Dr. Varun Gupta (MD Pharmacology)