


Tredaptive 20mg/1000mg Tablet
Laropiprant (20mg)+ Vitamin B3(Nicotinic Acid) (1000mg)
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Tredaptive 20mg/1000mg Tablet is a combination of two medicines used for reducing high triglycerides and cholesterol levels. It increases good cholesterol (HDL) and decreases the bad cholesterol (LDL) in the body.
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Jan 2026 | 03:33 PM (IST)
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Jan 2026 | 03:33 PM (IST)
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General Information
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Product introduction
Tredaptive 20mg/1000mg Tablet can be taken with food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine work better.
Stomach upset, tingling sensation of extremity, and flushing (sense of warmth in the face, ears, neck and trunk) are some common side effects of this medicine. These are usually mild but let your doctor know if they bother you or last more than a few days.
Before taking this medicine, tell your doctor if you have any liver or kidney disease. Inform your doctor if you are pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Stomach upset, tingling sensation of extremity, and flushing (sense of warmth in the face, ears, neck and trunk) are some common side effects of this medicine. These are usually mild but let your doctor know if they bother you or last more than a few days.
Before taking this medicine, tell your doctor if you have any liver or kidney disease. Inform your doctor if you are pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Uses of Tredaptive Tablet
Benefits of Tredaptive Tablet
High cholesterol
Tredaptive 20mg/1000mg Tablet effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart diseases and helps you remain healthier for longer. It also contains nutritional supplements that are essential for improving your overall health. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
Tredaptive 20mg/1000mg Tablet effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart diseases and helps you remain healthier for longer. It also contains nutritional supplements that are essential for improving your overall health. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
High triglycerides
Tredaptive 20mg/1000mg Tablet effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart diseases and helps you remain healthier for longer. It also contains nutritional supplements that are essential for improving your overall health. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
Tredaptive 20mg/1000mg Tablet effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart diseases and helps you remain healthier for longer. It also contains nutritional supplements that are essential for improving your overall health. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
Side effects of Tredaptive Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tredaptive
- Upset stomach
- Tingling sensation of extremity
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Headache
How to use Tredaptive Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tredaptive 20mg/1000mg Tablet should be taken with or after food.
How Tredaptive Tablet works
Tredaptive 20mg/1000mg Tablet is a combination of two medicines: Laropiprant and Vitamin B3(Nicotinic Acid). Vitamin B3(Nicotinic Acid) works by raising the level of "good cholesterol" (HDL) in the body. However, it may widen the blood vessels causing flushing (redness and warmth) of the skin. Laropiprant is added to prevent the release of chemicals that cause flushing.
Quick tips
- Tredaptive 20mg/1000mg Tablet reduces high cholesterol levels and lowers the risk of heart disease.
- Take Tredaptive 20mg/1000mg Tablet just after a meal or with a snack to avoid gastrointestinal problems.
- Inform your doctor if you experience fatigue, muscle weakness, or muscle pain.
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
- Lifestyle changes like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink may help this medicine work better.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Tredaptive 20mg/1000mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Tredaptive 20mg/1000mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Tredaptive 20mg/1000mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Tredaptive 20mg/1000mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Tredaptive 20mg/1000mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Tredaptive 20mg/1000mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Tredaptive 20mg/1000mg Tablet is not recommended in patients with severe liver disease and active liver disease.
Use of Tredaptive 20mg/1000mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
Related lab tests
References
- European Medicines Agency. Laropiprant / nicotinic acid. [Accessed 11 Apr. 2019] (online) Available from:
- Nicotinic Acid + Laropiprant. Northumberland, UK: Merck Sharp & Dohme Ltd. [Accessed 11 Apr. 2019] (online) Available from:
- Sanyal S, Kuvin JT, Karas RH. Niacin and laropiprant. Drugs Today (Barc). 2010;46(6):371-8. [Accessed 11 Apr.] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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