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MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
15 Jul 2019 | 05:17 PM (IST)
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Topocan 4 mg Injection

Prescription Required


Uses of Topocan Injection

Topocan Injection side effects

  • Tiredness
  • Vomiting
  • Weakness
  • Nausea
  • Abdominal pain
  • Indigestion
  • Decreased white blood cell count
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Injection site reactions (pain, swelling, redness)

How to use Topocan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Topocan Injection works

Topocan 4 mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Topocan Injection related warnings

Interaction with alcohol is unknown. Please consult your doctor.
Topocan 4 mg Injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Topocan 4 mg Injection is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Do not drive unless you are feeling well.
Topocan 4 mg Injection can make you feel tired and this may affect your ability to drive.
Topocan 4 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Topocan 4 mg Injection may be needed. Please consult your doctor.
Use of Topocan 4 mg Injection is not recommended in patients with end-stage kidney disease.
Topocan 4 mg Injection is safe to use in patients with liver disease. No dose adjustment of Topocan 4 mg Injection is recommended.

What if you miss a dose of Topocan Injection?

If you miss a dose of Topocan 4 mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Topocan 4 mg Injection
Topotel 4mg Injection
Fresenius Kabi India Pvt Ltd
₹1793/ml of Injection
739% costlier

Expert Advice

  • Topocan 4 mg Injection helps treat ovarian cancer.
  • It is given by a drip into a vein (intravenous infusion).
  • Do not drive or operate machinery as Topocan 4 mg Injection may cause tiredness, drowsiness or weakness.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Patient Concerns

Questions Related to Topocan

My mother dignosis with stage4 ovarian cancer, 1st done on 24th of may 16, I need a alternative medicine parallelly
Dr. Manju Singh
I would like to recommend you that please continue your treatment as advice by your doctor.
ovarian cancer stage 3 c surgery done chemotheraphy done
Dr. Aanchal Maheshwari
C?se has to be seen in person before starting the treatment
Do you have any questions related to Topocan 4 mg Injection?


Q. How often is Topocan given?

Generally Topocan treatment is for 4 cycles of 21 day each, patient is given Topocan for first 5 days of each cycle

Q. Does Topocan cause hair loss?

Yes, Topocan may cause temporary hair loss

Q. Does Topocan cause flare reaction?

Yes, Topocan may cause flare reaction

Q. How long does Topocan take to work?

The drug may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles

Q. Is Topocan a vesicant?

Topocan is a vesicant (irritant)

Q. Is Topocan effective/ effective in ovarian cancer?

Yes Topocan is effective if used at prescribed doses for the prescribed duration as advised by your doctor

Q. What is Topocan chemotherapy?

It is a treatment therapy that includes Topocan with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer)

Q. How is Topocan administered?

Topocan is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1711-12.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1383.
  4. Topotecan hydrochloride. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1996 [revised 23 Apr. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Topotecan. Unterach, Austria: Ebewe Pharma; 1996 [revised Feb. 2014]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  7. U.S. National Library of Medicine. Topotecan. [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
SCO 857, Cabin No. 10, 2nd Floor, NAC, Manimajra, Chandigarh (U.T.), 160101, India
A licensed pharmacy from your nearest location will deliver Topocan 4mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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