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Tibsovo 250mg Tablet

Ivosidenib (250mg)
Genuine
Authenticity Assured
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Tibsovo 250mg Tablet is an anticancer medicine used to treat certain adults with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or previously treated locally advanced or metastatic cholangiocarcinoma.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 28 Aug 2026 | 01:04 AM (IST)
₹652458 MRP ₹7015687% off 
 
 
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General Information

The content is shown in English
Tibsovo 250mg Tablet image
Tibsovo 250mg Tablet image
Tibsovo 250mg Tablet image
Tibsovo 250mg Tablet image
Tibsovo 250mg Tablet image

Product introduction

Take Tibsovo 250mg Tablet exactly as prescribed by your doctor. It can be taken with or without food. However, avoid a high-fat meal, as it can increase the amount of medicine absorbed by your body. Continue taking this medicine for as long as your doctor recommends. For people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS), treatment is generally continued for at least 6 months. Attend all scheduled blood tests, electrocardiograms (ECGs), and follow-up appointments so your doctor can monitor your response to treatment and detect any side effects early.


The most common side effects of Tibsovo 250mg Tablet include tiredness, diarrhea, nausea, decreased appetite, joint pain, muscle pain, rash, cough, shortness of breath, abdominal pain, and mouth sores. Contact your doctor if any side effect becomes severe, does not improve, or interferes with your daily activities.


Before starting treatment, tell your doctor about all your medical conditions and medicines you are taking. Your doctor will perform electrocardiograms (ECGs) and blood tests before and during treatment to monitor your heart rhythm, blood counts, electrolyte levels, and overall health. Seek medical attention immediately if you develop symptoms of differentiation syndrome, such as fever, difficulty breathing, rapid weight gain, or swelling, as this can be serious and requires prompt treatment. Tell your doctor if you notice dizziness, fainting, or an irregular heartbeat, as Tibsovo 250mg Tablet may affect the heart's electrical activity. 

Uses of Tibsovo Tablet

  • Myelodysplastic syndrome : It is a group of bone marrow disorders in which the body does not produce enough healthy blood cells. In some people, MDS can progress to acute myeloid leukemia.
  • Cholangiocarcinoma
  • Acute Myeloid Leukemia

Benefits of Tibsovo Tablet

Myelodysplastic syndrome
Tibsovo 250mg Tablet helps treat adults with relapsed or refractory myelodysplastic syndromes (MDS) by targeting abnormal proteins that contribute to the disease. This may help improve the production of healthy blood cells.
Cholangiocarcinoma
Tibsovo 250mg Tablet helps treat previously treated locally advanced or metastatic cholangiocarcinoma by targeting abnormal proteins that promote cancer growth. This treatment helps slow disease progression and may delay further worsening of the cancer.
Acute Myeloid Leukemia
Tibsovo 250mg Tablet helps treat acute myeloid leukemia (AML) by targeting abnormal proteins that help cancer cells grow. It helps slow disease progression and supports the growth of healthier blood cells.

Side effects of Tibsovo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tibsovo
  • Tiredness
  • Diarrhea
  • Nausea
  • Joint pain
  • Muscle pain
  • Rash
  • Cough
  • Breathlessness
  • Abdominal pain
  • Sores

How to use Tibsovo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tibsovo 250mg Tablet may be taken with or without food.

How Tibsovo Tablet works

Tibsovo 250mg Tablet works by blocking an abnormal protein called isocitrate dehydrogenase-1 (IDH1) that helps certain cancer cells grow. By blocking this protein, Tibsovo 250mg Tablet slows the growth of cancer cells and supports the development of healthier cells. This helps slow disease progression.

Quick tips

  • Take Tibsovo 250mg Tablet at about the same time each day to help maintain consistent medicine levels in your body.
  • Tibsovo 250mg Tablet may be taken with or without food, but avoid high-fat meals, as they can increase the amount of medicine absorbed.
  • Keep all scheduled ECG appointments and blood tests so your doctor can monitor your heart rhythm and overall health during treatment.
  • Seek medical attention immediately if you develop symptoms of differentiation syndrome, such as fever, difficulty breathing, rapid weight gain, or swelling, as early treatment is essential.
  • Report symptoms such as dizziness, fainting, irregular heartbeat, muscle weakness, numbness, or tingling to your doctor promptly, as these may indicate serious side effects that require medical attention.
  • Use effective contraception during treatment and for the recommended period after your last dose if you or your partner can become pregnant. Discuss suitable contraceptive methods with your doctor before starting treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tibsovo 250mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Tibsovo 250mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Tibsovo 250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Tibsovo 250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Tibsovo 250mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Consult your doctor in case of severe kidney impairment.
Liver

Liver

SAFE IF PRESCRIBED
Tibsovo 250mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
Consult your doctor in case of severe liver impairment.

Frequently asked questions

Tibsovo 250mg Tablet can affect your heart rhythm and may also cause changes in your blood counts and electrolyte levels. Regular electrocardiograms (ECGs) and blood tests help your doctor monitor these changes and manage them early if needed.
Differentiation syndrome is a serious complication that can occur in people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) receiving Tibsovo 250mg Tablet. Contact your doctor immediately if you develop fever, difficulty breathing, rapid weight gain, swelling, low blood pressure, or reduced urination, as early treatment is important.
For people with AML or MDS, treatment is generally continued for at least 6 months, provided it is tolerated and the disease has not worsened. This allows enough time for the medicine to produce a clinical response.
Always tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, herbal products, and dietary supplements you are taking.
Contact your doctor immediately if you experience dizziness, fainting, palpitations, or an irregular heartbeat. These may be signs of changes in your heart rhythm that require prompt medical evaluation.
Although uncommon, Tibsovo 250mg Tablet may rarely cause Guillain-Barré syndrome, a serious nerve disorder. Seek medical attention immediately if you develop muscle weakness, numbness, tingling, or difficulty breathing.

Fact Box

Chemical Class

Pyridine derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Servier India Private Limited
Address: 1703, 17th Floor, Parinee Crescenzo, 'B' Wing, Plot No. 38 & 39 G Block behind MCA, MKC Bandra East, Mumbai 40051

Importer details

Name: Servier India Private Limited
Address: 1703, 17th Floor, Crescenzo Business District, 'B' Wing, Plot Nos. C38 & 39, 'G' Block, Behind MCA, Bandra Kurla Complex, Bandra (East), Mumbai 400 051, India.

Vendor Details

Country of origin: France
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