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Tetglob Injection is recommended for treatment of tetanus following injury in patients whose tetanus immunization is incomplete or uncertain. Tetanus causes convulsions (seizures) and severe muscle spasms that can be strong enough to cause bone fractures of the spine.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 15 Jul 2026 | 01:06 AM (IST)
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1 ml Injection
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General Information

Contains

Tetanus Immunoglobulin (250IU/ml)

Marketer

Bharat Serums & Vaccines Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Tetglob Injection image
Tetglob Injection image
Tetglob Injection image
Tetglob Injection image

Product introduction

Tetglob Injection provides immediate, short-term protection against the bacteria that causes tetanus (lockjaw). A single intramuscular (IM) injection is generally recommended for children and adults, with part of the dose infiltrated around the wound if it can be identified. This protection lasts long enough to protect your body until your body can produce its own antibodies against tetanus. It is to be administered only by or under the supervision of your doctor or other healthcare professional.


 


You may experience reactions such as slight soreness, pain and swelling at the site of injection injections and and slight temperature elevation. If you experience any othe symptoms on receiving the injection, let your doctor know. They may be able to help ways to manage the side effects.


 


Before receiving this injection, let your doctor know if you have any bleeding disorders. Avoid receiving the injection if you have a known history of allergy with this medicine. Pregnant and breastfeeding women should consult their doctors before receiving this injection.

Uses of Tetglob Injection

Benefits of Tetglob Injection

Treatment of Tetanus
Tetanus causes a locked jaw, thus making it impossible to breathe, open the mouth to eat or swallow. Tetglob Injection helps the body produce substances that resist infection from bacteria causing tetanus. Consult your doctor if you have any doubts.

Side effects of Tetglob Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tetglob
  • Injection site reactions (pain, swelling, redness)
  • Increased body temperature

How to use Tetglob Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tetglob Injection works

Tetglob Injection contains tetanus antibodies. It works by giving your body the antibodies it needs to protect it against tetanus infection.

Quick tips

  • Tetglob Injection is given to prevent tetanus infection.
  • It is to be given by a doctor or nurse in a hospital setting.
  • Inform your doctor if you are suffering from any blood disorders before taking Tetglob Injection.
  • Tell your doctor if you are pregnant, think you may be pregnant, or are breastfeeding before this medicine is injected.
     

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tetglob Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Tetglob Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Tetglob Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Tetglob Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Tetglob Injection in patients with liver disease.

Frequently asked questions

Tetanus is caused by a toxin (poison) produced by the bacterium Clostridium tetani. The C. tetani bacteria cannot grow in the presence of oxygen. They produce spores that are very difficult to kill as they are resistant to heat and many chemical agents.
C. tetani spores can be found in soil, dust and manure of many household and farm animals and humans. The bacteria usually enter the human body in the presence of anaerobic (low oxygen) conditions through an open wound or puncture in the skin . These are the only favourable conditions for C. tetani to grow. It must be noted that tetanus does not spread from person to person.
It may take around 3 to 21 days for the first symptoms to develop (incubation period). On an average, the symptoms usually appear on day 8. However, the time depends upon the site of infection which means if the injury site is far from the central nervous system, the longer will be the incubation period. The rate of risk with tetanus increases with a shorter incubation period.
An early symptom of tetanus includes spasm of the jaw muscles which is then followed by stiffness of the neck, difficulty in swallowing and stiffness of the abdominal muscles. Other signs include fever, sweating, elevated blood pressure and rapid heart rate. Spasms often occur, which may last for several minutes and continue for 3–4 weeks. Complete recovery, if it occurs, may take months altogether.
Yes, tetanus can be fatal. In recent years, tetanus has been fatal in about 10% to 20% of reported cases.
No, there is no cure for tetanus once a person develops symptoms, just supportive treatment and management of complications. The best treatment of tetanus is its prevention through immunization.
Tetglob Injection is administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. It is given either in the thigh muscle (for infants and young toddlers) or in the deltoid muscle (for older children and adults). Follow your doctor’s instructions carefully to get maximum benefit from Tetglob Injection.
Tetglob Injection should not be given to someone who is suffering from any blood disorders which interfere with clotting or if a person is allergic to any of the ingredients of Tetglob Injection. Consult your doctor if you are not sure.
Tetglob Injection is stored in the refrigerator (2-8°C). However, it may be stored at room temperature (25°C), in the dark for a short span of time (about a week), and this will not damage the medicine usually. But, it should be protected from direct sunlight and must not be freezed either.
No. You should not use Tetglob Injection if the medicine has changed colors or has particles in it. Normally, Tetglob Injection is a clear to slightly cloudy, colorless to pale yellow sterile solution, available as single dose vials. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better that you discard the solution and go for another vial.
Tetglob Injection should not be given to someone who is suffering from any blood disorders which interfere with clotting or if a person is allergic to any of the ingredients of Tetglob Injection. Consult your doctor if you are not sure.
Tetglob Injection is stored in the refrigerator (2-8°C). However, it may be stored at room temperature (25°C), in the dark for a short span of time (about a week), and this will not damage the medicine usually. But, it should be protected from direct sunlight and must not be freezed either.
No. You should not use Tetglob Injection if the medicine has changed colors or has particles in it. Normally, Tetglob Injection is a clear to slightly cloudy, colorless to pale yellow sterile solution, available as single dose vials. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better that you discard the solution and go for another vial.
Tetanus is caused by a toxin (poison) produced by the bacterium Clostridium tetani. The C. tetani bacteria cannot grow in the presence of oxygen. They produce spores that are very difficult to kill as they are resistant to heat and many chemical agents.
C. tetani spores can be found in soil, dust and manure of many household and farm animals and humans. The bacteria usually enter the human body in the presence of anaerobic (low oxygen) conditions through an open wound or puncture in the skin . These are the only favourable conditions for C. tetani to grow. It must be noted that tetanus does not spread from person to person.
It may take around 3 to 21 days for the first symptoms to develop (incubation period). On an average, the symptoms usually appear on day 8. However, the time depends upon the site of infection which means if the injury site is far from the central nervous system, the longer will be the incubation period. The rate of risk with tetanus increases with a shorter incubation period.
An early symptom of tetanus includes spasm of the jaw muscles which is then followed by stiffness of the neck, difficulty in swallowing and stiffness of the abdominal muscles. Other signs include fever, sweating, elevated blood pressure and rapid heart rate. Spasms often occur, which may last for several minutes and continue for 3–4 weeks. Complete recovery, if it occurs, may take months altogether.
Yes, tetanus can be fatal. In recent years, tetanus has been fatal in about 10% to 20% of reported cases.
No, there is no cure for tetanus once a person develops symptoms, just supportive treatment and management of complications. The best treatment of tetanus is its prevention through immunization.
Tetglob Injection is administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. It is given either in the thigh muscle (for infants and young toddlers) or in the deltoid muscle (for older children and adults). Follow your doctor’s instructions carefully to get maximum benefit from Tetglob Injection.
Yes, Tetglob Injection can be taken by a pregnant woman. Cases of any fetal abnormalities in pregnant women have not been reported with the use of Tetglob Injection. All pregnant women should receive Tetglob Injection combined with other vaccines during pregnancy, preferably early between 27 and 36 weeks’ gestation. If a new mother hasn’t been vaccinated with Tetglob Injection, she should receive it before hospital discharge. She can take Tetglob Injection even if she is breastfeeding.

Fact Box

Chemical Class

Immunoglobulins

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Immunoglobulin

Related lab tests

Complete Blood Count

References

  1. Human tetanus immunoglobulin [EMC SmPC]. Elstree, Hertfordshire: Bio Products Laboratory Limited; 1992 [revised Oct. 2014]. [Accessed 31 Jan. 2020] (online) Available from:
  2. Tetanus Immunoglobulin I.P. (Human) [Prescribing Information]. Ambernath, Maharashtra: Serum Institute of India. [Accessed 19 Oct. 2023] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: Plot No. K-27, K-27 Part and K-27/1, Anand Nagar, Jambivili Village, Additional MIDC, Ambernath (East), Thane 421500, Maharashtra State, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Tetglob Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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