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Talendol Plus Tablet

Written By Dr. Mayank, Pharm.D
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 23 Sep 2025 | 05:13 PM (IST)
Talendol Plus Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.
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Talendol Plus Tablet image
Talendol Plus Tablet image

Product introduction

Talendol Plus Tablet also helps by improving muscle control and reducing the stiffness of the muscle. It may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Talendol Plus Tablet

Benefits of Talendol Plus Tablet

Schizophrenia
Schizophrenia is a long-term mental health condition that affects how a person thinks, feels, and behaves. It can cause symptoms like hallucinations (seeing or hearing things that aren't there), delusions, and severe mood or behavior changes. Talendol Plus Tablet helps manage the core symptoms of schizophrenia by balancing brain chemicals involved in mood and thinking, and reduces movement-related side effects often caused by antipsychotic treatment. This medicine helps improve daily functioning, thinking clarity, and emotional stability in individuals living with schizophrenia.

Side effects of Talendol Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Talendol Plus
  • Nausea
  • Constipation
  • Dryness in mouth
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Increased prolactin level in blood
  • Dizziness
  • Blurred vision
  • Nervousness

How to use Talendol Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Talendol Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Talendol Plus Tablet works

Talendol Plus Tablet is a combination of two medicines: Haloperidol and Trihexyphenidyl. Haloperidol is a typical antipsychotic. It works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is added to treat and prevent these side effects.

Quick tips

  • Talendol Plus Tablet is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug induced abnormal movements.
  • Be cautious while driving or doing anything that requires concentration as Talendol Plus Tablet can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication as it may lower its efficacy.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Talendol Plus Tablet without talking to your doctor first as it may cause worsening of symptoms.
  • Talendol Plus Tablet is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug induced abnormal movements.
  • Be cautious while driving or doing anything that requires concentration as Talendol Plus Tablet can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication as it may lower its efficacy.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Talendol Plus Tablet without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
Talendol Plus Tablet may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Talendol Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Talendol Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If Talendol Plus Tablet is used, monitor the baby for excessive sleepiness.
Driving

Driving

UNSAFE
Talendol Plus Tablet may cause side effects which could affect your ability to drive.
Talendol Plus Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Talendol Plus Tablet in patients with kidney disease. Please consult your doctor.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver

Liver

CAUTION
Talendol Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Talendol Plus Tablet may be needed. Please consult your doctor.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Talent Healthcare
Address: Chetan Gandhi, Plot No. 66-67, SIDCUL Sector 6A, IIE , Haridwar - 249403, Uttarakhand, India

Vendor Details

Country of origin: India
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