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Sysonide Cream

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 11 Mar 2026 | 09:48 PM (IST)
Sysonide Cream is a topical steroid use for the treatment of skin conditions with inflammation and itching. It provides relief from swelling, redness, and itching in the affected area by inhibiting the release of substances that cause inflammation.
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Sysonide Cream
Sysonide Cream
tube of 10 gm Cream
₹81.4
₹89.06
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Same composition
Desowen Cream
Desowen Cream
tube of 10 gm Cream
by Galderma India Pvt Ltd
Get in 30 mins
₹256
₹21.8 per gm

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General Information

The content is shown in English
Sysonide Cream image
Sysonide Cream image

Product introduction

Sysonide Cream is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor.

Using the medicine may cause burning sensation, irritation, redness, and swelling at the site of application, and rash. These are temporary and usually resolve with time. However, if they persist or worsen, let your doctor know. The medicine is not recommended for pregnant women. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.

Uses of Sysonide Cream

  • Treatment of Skin conditions with inflammation & itching

Benefits of Sysonide Cream

Treatment of Skin conditions with inflammation & itching
Sysonide Cream is effective in treating skin conditions with inflammation and itching such as eczema, psoriasis, and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin.

When used correctly it is a safe and effective treatment. In treating psoriasis, it reduces the scaly, itchy patches which may develop on the elbows, knees, scalp, and other parts of the body. In treating eczema and dermatitis, it reduces the redness, rash, pain, or itchiness caused by your skin’s reaction to an irritant. It thus improves your self-esteem and confidence as your appearance changes.

You should always use the cream or ointment as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.

Side effects of Sysonide Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sysonide
  • Application site reactions (burning, irritation, itching and redness)
  • Rash

How to use Sysonide Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Sysonide Cream works

Sysonide Cream is a mild to moderate strength steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy.

Quick tips

  • Sysonide Cream is used to treat the redness, swelling, itching, and discomfort of various skin conditions.
  • It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.
  • Don't use it more often or for longer than advised by your doctor.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become infected you should stop using Sysonide Cream and consult your doctor.
  • Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Sysonide Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Sysonide Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

No, Sysonide Cream is not safe for babies. It is a corticosteroid and is not approved to be used in children less than 3 months of age. In babies, the absorption of Sysonide Cream is greater as compared to adults which might lead to systemic absorption (absorbed throughout the body) and effects like Adrenal (glands producing steroids) suppression, symptoms of Cushing’s syndrome, high blood sugar, facial swelling, glycosuria (excretion of glucose in urine), withdrawal (weakness, fatigue, decreased appetite, weight loss, nausea, vomiting, diarrhea, abdominal pain), and growth retardation in children.
Yes, Sysonide Cream can cause skin irritation. Though the chances are rare, the irritation can be due to the hypersensitivity of the person towards the medication or any added excipient of the drug. Allergy to corticosteroids may generally appear as inability of the wounds to heal. If symptoms like these appear, then consult your doctor immediately after discontinuing the medicine. The doctor will start appropriate therapy accordingly.
It is a steroid which is used on the skin to treat mild or moderate atopic dermatitis in patients aged 3 months or more. It suppresses your immunity and associated inflammation, thereby relieving inflammatory conditions. Long-term usage should be avoided and do consult your physician before the start of therapy or in case of any skin reaction. Also, you must consult your physician in case your symptoms do not improve with the medication.
No, it is not an over the counter drug. Therefore, you cannot buy this medicine without a prescription. It is a corticosteroid and it suppresses your immunity and also has numerous metabolic side effects hence is not recommended for a long period. Moreover, you should take this medicine only if prescribed by your doctor.
Yes, Sysonide Cream can be applied on the face but with certain precautions. Do not directly apply it on the face. If it is in foam form, dispense it on your hands first and gently massage over the affected areas of the face. It is for external use only. Avoid contact with your eyes or other mucous membranes. Wash your hands after use. Use this medicine exactly as advised by the doctor. Do consult your physician before the start of therapy.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Glucocorticoids
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hacks & Slacks Healthcare
Address: Main Bazaar, Bhawanigarh-148026 Punjab, India

Vendor Details

Country of origin: India
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