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SUPIME 500MG/250MG INJECTION

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MRP: Rs. 135 for 1 vial(s) (10 ML injection each)
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Composition for SUPIME

Cefepime(500 mg),Sulbactam(250 mg)

food interaction for SUPIME

alcohol interaction for SUPIME

pregnancy interaction for SUPIME

lactation interaction for SUPIME

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Supime 500mg/250mg injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for SUPIME

Cefepime(500 mg)

Uses

Cefepime is used in the treatment of bacterial infections.

How it works

Cefepime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Vomiting, Nausea, Itchy rash, Acne-like rash, Bloody diarrhea, Confusion, Convulsion, Shortness of breath, Sore mouth, Sore throat, Stomach pain, Watery diarrhoea, Chills, Fever
Sulbactam(250 mg)

Uses

Sulbactam is used in the treatment of bacterial infections.

How it works

Sulbactam belongs to group of medicines called betalactamase Inhibitor with very weak action against bacteria.  Beta-lactamase inhibitors are available only in fixed combinations with specific penicillins (beta-lactam antibiotics) such as amoxicillin, ampicillin, piperacillin, and ticarcillin. It works by preventing destruction of beta-lactam antibiotics from chemicals released from bacteria and extends their spectrum of activity.

Common side effects

Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing

SUBSTITUTES for SUPIME

No substitutes found

Expert advice for SUPIME

  • Do not start or continue the cefepime and consult your doctor if you have kidney, liver or blood clotting disorder, stomach or bowel problems, poor nutrition, or if you are taking drugs like aminoglycosides (e.g. gentamycin) and diuretics (e.g. furosemide).
  • Caution should be taken when given to the children < 2 months old or to patients with diabetes as it may affect the results for urine glucose tests.

Frequently asked questions for SUPIME

Cefepime

Q.Is cefepime beta lactam, penicillin, or sulfa drug?
Cefepime does not contain sulfa and is not a penicillin drug. It is a beta lactam cephalosporin antibiotic

Q.Is cefepime broad spectrum bacteriostatic or bactericidal?
Cefepime is a broad spectrum bactericidal antibiotic

Q.Is cefepime compatible with lactated ringer's, normal saline, or vancomycin?
Cefepime is compatible with lactated ringer's or normal saline. Solutions of cefepime should not be added to vancomycin. However, if concurrent therapy with cefepime is indicated, vancomycin can be administered separately. Please consult your doctor before taking the drug

Q.Is cefepime a vesicant?
No, cefepime is not a vesicant drug

Q.What organisms does cefepime cover?
Cefepime is mainly effective against methicillin-sensitive Staphylococcus aureus (mssa), gram-negative bacteria, klebsiella, Group B streptococci but not effective against enterococcus, methicillin-resistant Staphylococcus aureus (mrsa), or anaerobes such as mycoplasma.

Sulbactam

Q.Is sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor

Q.What is sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins

Q.Is sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.

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Content on this page was last updated on 02 December, 2014, by Dr. Varun Gupta (MD Pharmacology)