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Supexa-OD 60 Tablet is an oral anticoagulant indicated to prevent stroke and blood clots in nonvalvular atrial fibrillation and treat deep vein thrombosis and pulmonary embolism. It inhibits Factor Xa, an essential enzyme in the formation of a clot.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Dec 2025 | 05:44 PM (IST)
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The content is shown in English
Supexa-OD 60 Tablet image
Supexa-OD 60 Tablet image
Supexa-OD 60 Tablet image

Product introduction

For maximum protection against stroke or clot recurrence, Supexa-OD 60 Tablet should be taken as directed, at the same time each day. Stopping the medication abruptly or skipping doses could raise the risk of dangerous blood clots. When a dose is forgotten, take it as soon as possible on the same day, but avoid doubling up. Follow-up visits and checks for signs of bleeding or clotting should be conducted during therapy.


Common side effects of Supexa-OD 60 Tablet include bleeding, rash, anemia, and increased liver tests. If you have concerns about these effects or experience any unusual symptoms, consult your doctor for guidance.


Supexa-OD 60 Tablet is contraindicated in patients with pathologically active bleeding, including gastrointestinal bleeding or recent hemorrhagic stroke. It must not be administered in patients with a mechanical heart valve or in moderate to severe mitral stenosis since it is not established in its safety and effectiveness in these conditions. Caution is exercised in patients with severe renal impairment or hepatic illness with coagulopathy, in whom bleeding risk is higher. Supexa-OD 60 Tablet must not also be started in patients with CrCl >95 mL/min when given for nonvalvular atrial fibrillation, as a decrease in the efficacy of preventing stroke exists.

Benefits of Supexa Tablet

Prevention of Deep vein thrombosis
Deep vein thrombosis is the formation of blood clots in deep veins, usually in the legs. These clots can cause swelling, pain, and may travel to the lungs, leading to serious complications. After an initial course of injectable anticoagulants, Supexa-OD 60 Tablet is used to help prevent new clots and reduce the chances of DVT recurrence.
Prevention of Pulmonary embolism
Pulmonary embolism occurs when a blood clot blocks an artery in the lungs, often originating from a DVT. This can lead to chest pain, breathing difficulty, and even be life-threatening. Supexa-OD 60 Tablet, after initial injectable therapy, works by preventing further clot formation, reducing the risk of recurrent PE, and supporting safer recovery.
Stroke prevention
Some strokes are caused by blood clots that form due to an irregular heartbeat not related to heart valve problems (nonvalvular atrial fibrillation, or NVAF). Supexa-OD 60 Tablet is used to prevent these types of strokes by reducing the risk of clot formation in the blood.

Side effects of Supexa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Supexa
  • Increased bleeding tendency
  • Rash
  • Abnormal liver function tests
  • Anemia (low number of red blood cells)

How to use Supexa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Supexa-OD 60 Tablet may be taken with or without food.

How Supexa Tablet works

Supexa-OD 60 Tablet is a direct oral anticoagulant (DOAC) that acts to selectively block Factor Xa, a central enzyme involved in the coagulation cascade of the blood. Inhibiting Factor Xa prevents the conversion of prothrombin into thrombin, which is required for clot formation. This prevents the formation of dangerous blood clots in diseases such as nonvalvular atrial fibrillation, deep vein thrombosis, and pulmonary embolism. Its targeted action ensures effective anticoagulation with consistent outcomes and fewer risks of specific bleeding complications than conventional blood thinners.

Quick tips

  • Take Supexa-OD 60 Tablet at the same time every day to maintain consistent blood levels.
  • Avoid high-risk activities; Supexa-OD 60 Tablet may increase bleeding risk, so be cautious with activities that may lead to injury or cuts.
  • If you plan surgeries, dental work, or start any new medication, your doctor must be informed to manage bleeding risks.
  • Regular exercise helps reduce clot risk, especially on long flights or bed rest.
  • Periodic kidney tests are advised, especially for older adults or those with kidney disease.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Supexa-OD 60 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Supexa-OD 60 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Supexa-OD 60 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Supexa-OD 60 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Supexa-OD 60 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Supexa-OD 60 Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

No, stopping Supexa-OD 60 Tablet without medical advice may increase your risk of stroke or clot recurrence. Always consult your doctor first.
Certain medications, like NSAIDs or antiplatelet drugs, can increase bleeding risk. Always inform your doctor about all medications you are taking.
Take the missed dose as soon as you remember on the same day. Do not take two doses the next day to make up for a missed one.
Watch for unusual bleeding (nosebleeds, bloody urine/stools), severe headaches, dizziness, or shortness of breath, and seek help immediately.
Duration depends on your condition. For DVT or PE, it is usually several months. For atrial fibrillation, long-term use may be required.

Fact Box

Chemical Class

Gamma amino acids and derivatives

Habit Forming

No

Action Class

Oral Factor Xa Inhibitors
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zuventus Healthcare Ltd
Address: 5119, Oberoi Garden Estate, Chandivali, Andheri E, Mumbai

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Supexa-OD 60 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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