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Simultin 250 mg/400 mg Tablet

Mefenamic Acid (250mg)+ Ibuprofen (400mg)

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Simultin 250 mg/400 mg Tablet is a medicine used in the treatment of abdominal cramps. It relaxes the muscles in the stomach or intestine and stops sudden muscle contractions, thereby relieving cramps, pain, bloating, and discomfort.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Nov 2026 | 01:03 AM (IST)

₹37.7 MRP ₹418% off

(Inclusive of applicable taxes)

Gurgaon

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Flat ₹50 cashback. T&C Apply*

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Get up to ₹150 cashback on a minimum order value (MOV) of ₹499 and above, valid once per customer.

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General Information

Contains

Mefenamic Acid (250mg)+ Ibuprofen (400mg)

Marketer

Dales Laboratories Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Simultin 250 mg/400 mg Tablet is best to take with food. Take it in the dose and duration as directed by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have any medical conditions or disorders. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment.

Uses of Simultin Tablet

Abdominal cramp

Benefits of Simultin Tablet

Abdominal cramp
Simultin 250 mg/400 mg Tablet gives relief from abdominal pain and cramps and works best if they are used when the first signs of pain occur. It slows the natural movements of the gut and relaxes the muscles in the stomach and intestines. It also lowers the level of certain chemicals in the body that causes pain. Take this medicine before meals and at bedtime or as directed by your doctor.

Side effects of Simultin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Simultin

Nausea
Vomiting
Diarrhea
Indigestion
Upset stomach
Loss of appetite
Heartburn

How to use Simultin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simultin 250 mg/400 mg Tablet should be taken with or after food.

How Simultin Tablet works

Simultin 250 mg/400 mg Tablet is a combination of two medicines: Mefenamic Acid and Ibuprofen which relieve abdominal pain. They.are non-steroidal antiinflammatory drugs (NSAIDs) which work by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick tips

You have been prescribed Simultin 250 mg/400 mg Tablet to relieve abdominal cramps.
It is best to take it when the first sign of pain occurs.
Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
If you get diarrhea while taking this medicine, consult your doctor immediately.
Do not take indigestion remedies (antacids) within two hours of taking Simultin 250 mg/400 mg Tablet.
If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Simultin 250 mg/400 mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Simultin 250 mg/400 mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Simultin 250 mg/400 mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Simultin 250 mg/400 mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Simultin 250 mg/400 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Simultin 250 mg/400 mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.

Liver

UNSAFE

Simultin 250 mg/400 mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Simultin 250 mg/400 mg Tablet is not recommended in patients with severe liver disease.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

User feedback

Patients taking Simultin 250 mg/400 mg Tablet

Once A Day

80%

Twice A Day

20%

What are you using Simultin Tablet for?

Dental pain

100%

How much was the improvement?

Poor

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dales Laboratories Pvt Ltd
Address: 101, Abhishek, C/5, Dalia Industrial Estate, Off Link Road, Near OberoiChambers, Andheri(West), Mumbai - 400058, India

Vendor Details

Country of origin: India

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Simultin 250 mg/400 mg Tablet

Simultin 250 mg/400 mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Simultin Tablet

Benefits of Simultin Tablet

Side effects of Simultin Tablet

How to use Simultin Tablet

How Simultin Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Simultin 250 mg/400 mg Tablet

What are you using Simultin Tablet for?

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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