


Simclox 250mg/250mg Injection
Amoxycillin (250mg)+ Cloxacillin (250mg)
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Simclox 250mg/250mg Injection is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 12 Jul 2026 | 01:03 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 12 Jul 2026 | 01:03 AM (IST)
₹15.2 MRP ₹165% off
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General Information
Contains
Amoxycillin (250mg)+ Cloxacillin (250mg)
Marketer
Biomedica International
Storage
Store below 30°C
The content is shown in English



Product introduction
Simclox 250mg/250mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of Simclox Injection
Benefits of Simclox Injection
Bacterial infections
Simclox 250mg/250mg Injection is a medicine that helps to kill the bacteria that cause different infections and treats your infection. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Simclox 250mg/250mg Injection is a medicine that helps to kill the bacteria that cause different infections and treats your infection. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
How to use Simclox Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Simclox Injection works
Simclox 250mg/250mg Injection is a combination of two antibiotics: Amoxycillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.
All substitutes for Simclox 250mg/250mg Injection
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- You have been prescribed this combination medicine to treat bacterial infections.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect. Taking probiotics along with Simclox 250mg/250mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
- Stop taking Simclox 250mg/250mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Simclox 250mg/250mg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Simclox 250mg/250mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
Simclox 250mg/250mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
CONSULT YOUR DOCTOR
It is not known whether Simclox 250mg/250mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Simclox 250mg/250mg Injection can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.
Simclox 250mg/250mg Injection can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.

Kidney
CAUTION
Simclox 250mg/250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine.
Regular monitoring of kidney function tests is advised while taking this medicine.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Simclox 250mg/250mg Injection in patients with liver disease.
Regular monitoring of liver function tests is advised while taking this medicine.
Regular monitoring of liver function tests is advised while taking this medicine.
Frequently asked questions
Usually, Simclox 250mg/250mg Injection starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop taking Simclox 250mg/250mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Related lab tests
References
- Amoxicillin sodium. Wrexham: Wockhardt UK Ltd.; 2008 [revised 18 Dec. 2017]. [Accessed 08 Apr. 2019] (online) Available from:
- ScienceDirect. Cloxacillin [Accessed 29 Mar. 2019 (online) Available from:
- Amoxicillin. Fossignano: Istituto Biochimico Italiano; 2017. [Accessed 08 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Biomedica International
Address: Industrial Complex, Humbran, Ludhiana-141110, Punjab
Address: Industrial Complex, Humbran, Ludhiana-141110, Punjab
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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