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Silodal M 50 Tablet ER is a combination medicine that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)
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Silodal M 50 Tablet ER image
Silodal M 50 Tablet ER image
Silodal M 50 Tablet ER image
Silodal M 50 Tablet ER image
Silodal M 50 Tablet ER image

Product introduction

Silodal M 50 Tablet ER is advised to take it in a dose and duration as per prescription. It may be taken with or without food. Take it regularly at the same time each day. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.

Some common side effects of this medicine are retrograde ejaculation, dizziness, diarrhea, orthostatic hypotension, headache, nasopharyngitis, and nasal congestion. If any of the side effects persist or bother you, you must consult the doctor without delay.

Simple lifestyle changes can help you manage your symptoms better. Try to urinate as soon as you feel the urge, however, never strain or push to empty your bladder. You should avoid drinking caffeinated or alcoholic drinks at night and a few hours before going to bed or going out.

Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you have to undergo eye surgery due to cataracts or glaucoma then inform your eye doctor about the usage of this medicine. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor’s advice.

Uses of Silodal M Tablet

Benefits of Silodal M Tablet

Benign prostatic hyperplasia
When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and the need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Silodal M 50 Tablet ER works by relaxing muscles in the bladder and prostate. So, it can rapidly relieve the symptoms and make it easier for you to urinate. It also helps to treat uncontrollable contractions (spasms) of the bladder muscles that cause frequent urination, urgent need to urinate, and inability to control passing of urine. It also relieves painful, or frequent urination and reduces urgency to urinate. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Silodal M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Silodal M
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Nasal congestion (stuffy nose)
  • Retrograde ejaculation
  • Dizziness
  • Diarrhea
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Headache

How to use Silodal M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Silodal M 50 Tablet ER may be taken with or without food.

How Silodal M Tablet works

Silodal M 50 Tablet ER is a combination of mirabegron and silodosin. Mirabegron relaxes the bladder muscles to prevent urgent, frequent, or uncontrolled urination. Silodosin relaxes the muscles of the bladder and prostate.

Quick tips

  • Silodal M 50 Tablet ER may raise your blood pressure. Monitor your blood pressure regularly.
  • Avoid drinking too much water before going to bed as it will increase your urge to go to the toilet and thus disturb your sleep.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Silodal M 50 Tablet ER. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Silodal M 50 Tablet ER is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Silodal M 50 Tablet ER should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CAUTION
Silodal M 50 Tablet ER may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Silodal M 50 Tablet ER should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Silodal M 50 Tablet ER should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Yes, this medicine may cause a drop in the blood pressure. This most commonly occurs while taking the first dose of this medicine. Hence, you should be cautious while driving, operating any machinery, or doing any important work during the initial days of the treatment. Consult your doctor before you start taking this medication.
You must consult your doctor before you start taking these medications. Silodal M 50 Tablet ER can sometimes cause low blood pressure and fainting. Taking sildenafil along with Silodal M 50 Tablet ER can further deteriorate the condition. It could also lead to increased chances of a drop in blood pressure in a few sensitive patients. As a result, there could be an increase in the chances of fainting which could be dangerous.
No, do not stop taking Silodal M 50 Tablet ER even if you start feeling better. This medicine does not cure prostatic hyperplasia but relieves the symptoms like painful, frequent urination and reduces the urgency to urinate. Stopping the treatment may result in the recurrence of prostatic hyperplasia symptoms.

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UROLOGY
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Silodal M 50 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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