Sigmadol P 37.5mg/325mg Tablet is a combination pain-relieving medicine used to manage moderate to severe pain. This includes pain after surgery, injury, or severe muscle pain. It works by acting on the brain to reduce the perception of pain and provide effective relief.
Sigmadol P 37.5mg/325mg Tablet should be taken in the dose and duration advised by your doctor. It may be taken with or without food. If it causes stomach upset, take it with food. Take it exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Common side effects of this medicine include nausea, vomiting, dry mouth, dizziness, and constipation in some patients. These are usually mild and tend to resolve over time. If any of these side effects persist or get worse, consult your doctor for guidance. Inform your doctor immediately if you notice any rash or signs of an allergic reaction while taking this medicine. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. This medicine is not recommended for people with severe liver impairment or those with uncontrolled epilepsy.
Uses of Sigmadol P Tablet
Moderate to severe pain
Benefits of Sigmadol P Tablet
In Moderate to severe pain
Sigmadol P 37.5mg/325mg Tablet works by acting on the brain to alter pain perception and by blocking pain signals. This helps provide faster and more effective relief from intense pain. Timely pain control can improve mobility and support recovery. As a result, patients may experience greater comfort and improved ability to perform daily activities.
Side effects of Sigmadol P Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sigmadol P
Nausea
Vomiting
Dizziness
Constipation
Dryness in mouth
Sleepiness
Diarrhea
Abdominal pain
Indigestion
Flatulence
Headache
Trembling
Anxiety
Sleep disorder
Itching
How to use Sigmadol P Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sigmadol P 37.5mg/325mg Tablet may be taken with or without food.
How Sigmadol P Tablet works
Sigmadol P 37.5mg/325mg Tablet is a combination of two medicines: Tramadol and Paracetamol which relieve severe pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol works by blocking the release of certain chemical messengers that cause pain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Sigmadol P 37.5mg/325mg Tablet
Pregnancy
CONSULT YOUR DOCTOR
Sigmadol P 37.5mg/325mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
SAFE IF PRESCRIBED
Sigmadol P 37.5mg/325mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Driving
UNSAFE
Sigmadol P 37.5mg/325mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Sigmadol P 37.5mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Sigmadol P 37.5mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed. However, the use of Sigmadol P 37.5mg/325mg Tablet is not recommended in patients with severe liver disease or active liver disease.
What if you forget to take Sigmadol P Tablet?
If you miss a dose of Sigmadol P 37.5mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Consider taking Sigmadol P 37.5mg/325mg Tablet with milk or food to prevent stomach upset.
Sigmadol P 37.5mg/325mg Tablet may cause drowsiness, dizziness, or slowed reaction time, particularly when you first start taking it. It is recommended to avoid driving or operating heavy machinery until you are certain how it affects you.
Drink plenty of water and eat fiber-rich foods like fruits and vegetables to help prevent constipation, a common side effect of Sigmadol P 37.5mg/325mg Tablet.
Do not drink alcohol while taking Sigmadol P 37.5mg/325mg Tablet. Alcohol combined with this medicine can cause extreme drowsiness or dangerously slow your breathing.
During long-term treatment, your doctor may conduct regular blood tests to monitor your liver function.
Inform your doctor if you have a history of heart disease, high blood pressure, liver disease, kidney disease, epilepsy, or any breathing problems before taking Sigmadol P 37.5mg/325mg Tablet.
Do not stop taking Sigmadol P 37.5mg/325mg Tablet suddenly if you have been using it for more than a few days. Stopping it abruptly may lead to withdrawal symptoms such as anxiety, restlessness, sweating, insomnia, and gastrointestinal discomfort.
Fact Box
Habit Forming
Yes
Therapeutic Class
PAIN ANALGESICS
FAQs
What is Sigmadol P 37.5mg/325mg Tablet, and what is it used for?
Sigmadol P 37.5mg/325mg Tablet is a combination painkiller used for short-term relief of moderate to severe pain, such as pain after surgery, injury, or severe muscle and joint pain. Tramadol works by acting on pain receptors in the brain and spinal cord to reduce the intensity of pain. Paracetamol works by blocking certain chemical signals in the brain that cause pain and fever. Together, they provide stronger and faster relief than either medicine alone.
Who should not take Sigmadol P 37.5mg/325mg Tablet?
Sigmadol P 37.5mg/325mg Tablet should not be used by children under 12. It should also be avoided if you have severe asthma, breathing problems, liver disorders, or epilepsy. If you are pregnant or if you drink excessive alcohol, this medicine may not be safe for you. Consult your doctor and share your complete medical history before starting this medicine.
Is Sigmadol P 37.5mg/325mg Tablet habit-forming, and can it cause addiction with regular use?
Yes. Since Sigmadol P 37.5mg/325mg Tablet contains tramadol, which is an opioid painkiller, it may cause tolerance, dependence, or addiction if used for a long time. You may feel the need to take more than the prescribed dose or use it for reasons other than pain relief. Always use it only as directed by your doctor.
Can Sigmadol P 37.5mg/325mg Tablet cause drowsiness or dizziness that affects driving?
Yes. It may impair the mental and physical abilities needed for driving and operating heavy machinery. Side effects such as drowsiness, dizziness, blurred vision, and slowed reaction times are common, particularly at the start of treatment or after a dose increase. Avoid driving while taking Sigmadol P 37.5mg/325mg Tablet.
Is Sigmadol P 37.5mg/325mg Tablet safe for people with kidney or liver problems?
Both the kidney and liver play critical roles in processing and clearing this medicine from the body. If either organ is not functioning properly, the medicine can accumulate in the body, increasing the risk of serious side effects. If you have kidney or liver disease, take Sigmadol P 37.5mg/325mg Tablet only if your doctor prescribes it.
Can children or elderly patients take Sigmadol P 37.5mg/325mg Tablet?
Sigmadol P 37.5mg/325mg Tablet is contraindicated (must not be used) in all children under 12 years of age. It is also contraindicated in patients under 18 years of age who have had a tonsillectomy or adenoidectomy (throat or nose surgery), due to a significantly increased risk of life-threatening breathing problems. Elderly patients may take this medicine after consulting their doctor.
Is Sigmadol P 37.5mg/325mg Tablet safe for patients with a history of seizures or epilepsy?
Patients with epilepsy or a history of seizures may face an increased risk of experiencing a seizure while taking Sigmadol P 37.5mg/325mg Tablet. The seizure risk further increases when it is taken alongside certain medicines like antidepressants. Do not take Sigmadol P 37.5mg/325mg Tablet without consulting your doctor.
Can Sigmadol P 37.5mg/325mg Tablet cause constipation or difficulty in bowel movements?
Yes. Constipation is one of the most common side effects of Sigmadol P 37.5mg/325mg Tablet. Consult your doctor if constipation becomes severe or if you develop abdominal pain and bloating. If you notice that you have not had a bowel movement for 3 or more days, contact your doctor.
Can I stop taking Sigmadol P 37.5mg/325mg Tablet suddenly after using it for several days?
No. Do not stop taking Sigmadol P 37.5mg/325mg Tablet abruptly after taking it for more than a few days, as this may be unsafe. Because it is an opioid, the body can become physically dependent on it quickly. When the medicine is stopped suddenly, the body may produce withdrawal symptoms such as sweating, anxiety, insomnia, and tremors.
Can I use Sigmadol P 37.5mg/325mg Tablet for long-term management of chronic back pain?
No. Usually, doctors prescribe Sigmadol P 37.5mg/325mg Tablet for short-term use (generally up to a few days). In certain conditions, your doctor may prescribe it for longer durations depending on the severity of the condition and the type of diagnosis. If you have chronic back pain, discuss a comprehensive pain management plan with your doctor. Using opioids such as Sigmadol P 37.5mg/325mg Tablet as the primary long-term strategy is generally not recommended.
Is Sigmadol P 37.5mg/325mg Tablet the same as paracetamol?
No. Sigmadol P 37.5mg/325mg Tablet and paracetamol are not the same medicine, even though the former contains paracetamol as an ingredient. Paracetamol and Sigmadol P 37.5mg/325mg Tablet work in different ways in the body and should be taken only after consulting your doctor to avoid confusion and overdose.
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References
FDA approved prescribing information. Tramadol hydrochlorid; 1995 [revised May 2010]. [Accessed 24 Apr. 2019] (online) Available from:
Paracetamol. Barnstaple, Devon: Actavis UK Ltd.; 1980 [revised 23 Dec. 2016]. [Accessed 02 Apr. 2019] (online) Available from:
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