Setolac-P Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.
Setolac-P Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.
There is limited data on the side effects of Setolac-P Tablet. Let your doctor know if you experience any symptoms that bother you or worsen while taking the medicine. They may be able to suggest ways to treat or manage the side effects.
The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.
Setolac-P Tablet is a painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is used widely, and causes side effects very rarely if taken at the right dosage.
Take Setolac-P Tablet as prescribed to get the most benefits. Do not take it more or for longer than needed as that can be dangerous. In general, take the lowest dose that works for the shortest possible time.
Side effects of Setolac-P Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Setolac-P
Limited data available
How to use Setolac-P Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Setolac-P Tablet may be taken with or without food.
How Setolac-P Tablet works
Setolac-P Tablet is a combination of two medicines: Paracetamol and S-Etodolac. These medicines work by blocking the action of chemical messengers responsible for pain, fever, and inflammation (redness and swelling).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Setolac-P Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Setolac-P Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Setolac-P Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Setolac-P Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Setolac-P Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Setolac-P Tablet in patients with liver disease.
What if you forget to take Setolac-P Tablet?
If you miss a dose of Setolac-P Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
Avoid consuming alcohol when taking Setolac-P Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Setolac-P Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
User feedback
Patients taking Setolac-P Tablet
Twice A Day
55%
Once A Day
40%
Thrice A Day
4%
What are you using Setolac-P Tablet for?
Pain relief
67%
Others
33%
How much was the improvement?
Average
78%
Excellent
22%
What were the side-effects while using Setolac-P Tablet?
No Side Effec*
100%
*No Side Effect
How do you take Setolac-P Tablet?
With or witho*
100%
*With or without food
Please rate Setolac-P Tablet on price
Expensive
100%
FAQs
What is Setolac-P Tablet used for?
Setolac-P Tablet is used to relieve pain, swelling, stiffness, and inflammation linked to arthritis conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It may help with mild to moderate pain like headache, toothache, period pain, sore throat, and feverish body pain.
Who should not take Setolac-P Tablet?
Individuals should not take Setolac-P Tablet if they are allergic to etodolac, paracetamol, or any ingredient present in it. This medicine should also not be used if they have severe heart failure, current or repeated stomach/duodenal ulcers, bleeding, past serious reactions to aspirin/NSAIDs (e.g., wheezing, rash), severe liver or kidney failure, or are pregnant or breastfeeding unless your doctor decides it is essential.
What serious side effects of Setolac-P Tablet should I watch out for?
Serious side effects of Setolac-P Tablet include chest pain, stroke symptoms, passing black stools, vomiting blood, severe stomach pain, yellow eyes/skin (liver injury), trouble peeing, very little urine (kidney failure), severe rash, skin peeling, swelling of face/lips/tongue, severe headache, and fever with stiff neck (possible aseptic meningitis). Seek immediate medical attention if you experience any of these symptoms.
Can Setolac-P Tablet harm my stomach or cause bleeding?
Yes. Setolac-P Tablet can cause stomach or intestinal bleeding, ulcers, or holes at any time, with or without warning. If you notice blood in stool, black tarry stools, or vomit that looks like coffee grounds, stop the medicine and seek medical care immediately. This risk is higher with high doses or long-term use.
Does Setolac-P Tablet increase heart attack or stroke risk?
Setolac-P Tablet may be linked with a small increased risk of heart attack (myocardial infarction) or stroke, especially with higher doses or longer use. People with heart problems, high blood pressure, diabetes, high cholesterol, or who smoke should discuss risks with their doctor, and avoid taking more than prescribed, or for longer than advised.
What are the signs of liver or kidney damage I should watch for during Setolac-P Tablet treatment?
Setolac-P Tablet can affect the liver and kidneys. The signs of liver damage include yellowing of the eyes/skin, belly pain, abnormal liver tests, and severe tiredness. The signs of kidney damage include pain or difficulty passing urine, a change in urine color, and peeing much more or less than usual. Seek care urgently (can be serious, especially if too much Setolac-P Tablet is taken) if you notice any of these liver or kidney signs.
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References
Pareek A, Chandurkar N, Ambade R, et al. Efficacy and safety of etodolac-paracetamol fixed dose combination in patients with knee osteoarthritis flare-up: a randomized, double-blind comparative evaluation. Clin J Pain. 2010 Sep;26(7):561-6. [Accessed 31 Jan. 2026]. Available from: