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Septran Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Septran Tablet is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of the urinary tract, ear, and abdomen. It prevents the growth of microorganisms to cure the infection.
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General Information

Contains

Sulfamethoxazole (400mg)+ Trimethoprim (80mg)

Marketer

Koye Pharmaceuticals Pvt ltd

Storage

Store below 30°C
The content is shown in English
Septran Tablet image
Septran Tablet image

Product introduction

Septran Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It can be taken with or without food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.


Septran Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.


Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Septran Tablet

Benefits of Septran Tablet

Treatment of Bacterial infections
Infections caused by bacteria are known as bacterial infections. Septran Tablet is an antibiotic which is used to treat different types of bacterial infections. Septran Tablet works by stopping the growth of the bacteria. It is effective for bacterial infections of the lungs, throat, urinary tract, ear and stomach. It is advisable to continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed. Stopping it early may make the infection come back and difficult to treat.

Side effects of Septran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Septran
  • Decreased appetite
  • Red spots or bumps
  • Nausea
  • Vomiting
  • Increased potassium level in blood
  • Candida overgrowth
  • Headache
  • Rash
  • Diarrhea

How to use Septran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Septran Tablet should be taken with or after food.

How Septran Tablet works

Septran Tablet is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing folic acid, a nutrient required for bacterial multiplication. Together, they treat your infection effectively.

Quick tips

  • You have been prescribed Septran Tablet for the treatment of many types of bacterial infections.
  • Finish the prescribed course of Septran Tablet, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
  • Stop taking Septran Tablet and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Septran Tablet.
  • In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Septran Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Septran Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
There may be a possibility of skin rash in the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Septran Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Septran Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Septran Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Septran Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Septran Tablet is not recommended in patients with the severe liver disease.

Frequently asked questions

Septran Tablet is a combination of two medicines: Sulfamethoxazole+Trimethoprim. It is an antibiotic used to treat certain bacterial infections and works by stopping the growth of the bacteria causing the infection. It treats urinary tract infections, ear infections, enteritis (inflammation of the small intestine), pneumonia, traveler's diarrhea, and episodes of difficulty breathing in people with chronic (long-term) bronchitis.
Yes, Septran Tablet is safe to use in most patients. However, in some patients, it may cause some unwanted common side effects like Nausea, Vomiting, Skin rash, Allergic reaction. Inform your doctor as soon as possible if you experience any persistent problem while taking this medication.
Yes, the use of Septran Tablet can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods. If you start to experience vomiting, drink plenty of water or other fluids. Try small frequent sips of the liquid. Talk to your doctor if you have persistent vomiting and signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to a doctor.
Septran Tablet is contraindicated in patients with known allergy to any of the component or excipients of this medicine and in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia due to folate deficiency. The medicine is also contraindicated in pediatric patients less than 2 months of age and in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.
It is advised to not skip the dose. Skipping doses or not completing the full course of the medicine can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of it.
Yes, Septran Tablet does expire. The expiry date is written on the pack of the medicine and it refers to the last day of the month mentioned. Do not use Septran Tablet after the expiry date.
Septran Tablet is a combination of two medicines: Sulfamethoxazole and Trimethoprim. It is an antibiotic which treats certain bacterial infections and works by stopping the growth of the bacteria causing the infection.
Yes, the use of Septran Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.
Septran Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. It is also avoided in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia caused due to folate deficiency. The medicine is also harmful for pediatric patients less than 2 months of age and for patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.
No, do not stop taking Septran Tablet and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
No, do not stop taking Septran Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Take Septran Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

  1. Sulfamethoxazole and trimethoprim. [Accessed 10 Apr. 2019] (online) Available from:
  2. Sulfamethoxazole and trimethoprim. Philadelphia, PA: AR Scientific, INC; 2013. [Accessed 10 Apr. 2019] (online) Available from:
  3. Sulfamethoxazole and trimethoprim. Greenville, SC: PAI Pharma; 2025. [Accessed 08 Nov. 2025] (online). Available from:
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User feedback

Once A Day
100%
Bacterial infections
85%
Others
15%
Excellent
45%
Average
40%
Poor
15%
Vomiting
28%
No Side Effect
28%
Allergic reaction
17%
Nausea
11%
Skin rash
11%
With food
78%
With or without food
17%
Empty stomach
5%
Not Expensive
48%
Average
27%
Expensive
25%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Koye Pharmaceuticals Pvt ltd
Address: A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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