Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
User feedback
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Lalit Kanodia

MBA, MD Pharmacology

Last updated

12 Nov 2025 | 10:19 PM (IST)

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Septran DS 800mg/160mg Tablet

Prescription Required

NPPA Regulated

Marketer

RV LIFESCIENCES LIMITED

SALT COMPOSITION

Sulfamethoxazole (800mg) + Trimethoprim (160mg)

Storage

Store below 25°C

5% cheaper alternative available with same salt composition

Click here to view all substitutes

Product introduction

Septran DS 800mg/160mg Tablet is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of the urinary tract, ear, and abdomen. It prevents the growth of microorganisms to cure the infection.

Septran DS 800mg/160mg Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It can be taken with or without food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.

Septran DS 800mg/160mg Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Septran Tablet

Treatment of Bacterial infections

Benefits of Septran Tablet

In Treatment of Bacterial infections

Infections caused by bacteria are known as bacterial infections. Septran DS 800mg/160mg Tablet is an antibiotic which is used to treat different types of bacterial infections. Septran DS 800mg/160mg Tablet works by stopping the growth of the bacteria. It is effective for bacterial infections of the lungs, throat, urinary tract, ear and stomach. It is advisable to continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed. Stopping it early may make the infection come back and difficult to treat.

Side effects of Septran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Septran

Decreased appetite
Red spots or bumps
Nausea
Vomiting
Increased potassium level in blood
Candida overgrowth
Headache
Rash
Diarrhea

How to use Septran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Septran DS 800mg/160mg Tablet should be taken with or after food.

How Septran Tablet works

Septran DS 800mg/160mg Tablet is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing folic acid, a nutrient required for bacterial multiplication. Together, they treat your infection effectively.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Septran DS 800mg/160mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Septran DS 800mg/160mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
There may be a possibility of skin rash in the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Septran DS 800mg/160mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Septran DS 800mg/160mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Septran DS 800mg/160mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Septran DS 800mg/160mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Septran DS 800mg/160mg Tablet is not recommended in patients with the severe liver disease.

What if you forget to take Septran Tablet?

If you miss a dose of Septran DS 800mg/160mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Septran DS 800mg/160mg Tablet

₹2.31/Tablet

CO-Trimoxazole Double Strength Tablet

Cadila Pharmaceuticals Ltd

₹2.19/tablet

5% cheaper

Oriprim DS 800mg/160mg Tablet

Zydus Cadila

₹2.21/tablet

4% cheaper

Procotri 800mg/160mg Tablet

Steadfast Medishield Pvt Ltd

₹2.19/tablet

5% cheaper

Jolltrim-DS Tablet

Jolly Healthcare

₹2.18/tablet

6% cheaper

Quick tips

You have been prescribed Septran DS 800mg/160mg Tablet for the treatment of many types of bacterial infections.
Finish the prescribed course of Septran DS 800mg/160mg Tablet, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
Stop taking Septran DS 800mg/160mg Tablet and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Septran DS 800mg/160mg Tablet.
In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

My son is suffering from cold and fever. I want to give him septran so please advise what would be the appropriate dosage of septran

Dr. Gopal Bansilal Samdani

Paediatrics

Septran is prescription drug and antibiotics with many side effectsThere are many underlying causes of your symptoms. Specific treatment can not be given unless we establish exact underlying cause. Please consult Pediatrician. will take detail history and will examine your child in detail. At time may ask you relevant investigations if necessary. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

User feedback

Patients taking Septran DS 800mg/160mg Tablet

Once A Day

100%

What are you using Septran Tablet for?

Bacterial inf*

92%

Others

*Bacterial infections

How much was the improvement?

Excellent

49%

Average

30%

Poor

21%

What were the side-effects while using Septran DS 800mg/160mg Tablet?

Nausea

33%

Vomiting

33%

No Side Effec*

11%

Allergic reac*

11%

Skin rash

11%

*No Side Effect, Allergic reaction

How do you take Septran Tablet?

With food

62%

With or witho*

31%

Empty stomach

*With or without food

Please rate Septran DS 800mg/160mg Tablet on price

Not Expensive

47%

Expensive

28%

Average

25%

FAQs

What is Septran DS 800mg/160mg Tablet?

Septran DS 800mg/160mg Tablet is a combination of two medicines: Sulfamethoxazole+Trimethoprim. It is an antibiotic used to treat certain bacterial infections and works by stopping the growth of the bacteria causing the infection. It treats urinary tract infections, ear infections, enteritis (inflammation of the small intestine), pneumonia, traveler's diarrhea, and episodes of difficulty breathing in people with chronic (long-term) bronchitis.

Is it safe to use Septran DS 800mg/160mg Tablet?

Yes, Septran DS 800mg/160mg Tablet is safe to use in most patients. However, in some patients, it may cause some unwanted common side effects like Nausea, Vomiting, Skin rash, Allergic reaction. Inform your doctor as soon as possible if you experience any persistent problem while taking this medication.

Can the use of Septran DS 800mg/160mg Tablet cause nausea and vomiting?

Yes, the use of Septran DS 800mg/160mg Tablet can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods. If you start to experience vomiting, drink plenty of water or other fluids. Try small frequent sips of the liquid. Talk to your doctor if you have persistent vomiting and signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to a doctor.

Are there any specific contraindications associated with the use of Septran DS 800mg/160mg Tablet?

Septran DS 800mg/160mg Tablet is contraindicated in patients with known allergy to any of the component or excipients of this medicine and in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia due to folate deficiency. The medicine is also contraindicated in pediatric patients less than 2 months of age and in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

What should be avoided while taking the Septran DS 800mg/160mg Tablet?

It is advised to not skip the dose. Skipping doses or not completing the full course of the medicine can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of it.

Does Septran DS 800mg/160mg Tablet expire?

Yes, Septran DS 800mg/160mg Tablet does expire. The expiry date is written on the pack of the medicine and it refers to the last day of the month mentioned. Do not use Septran DS 800mg/160mg Tablet after the expiry date.

What is Septran DS 800mg/160mg Tablet?

Septran DS 800mg/160mg Tablet is a combination of two medicines: Sulfamethoxazole and Trimethoprim. It is an antibiotic which treats certain bacterial infections and works by stopping the growth of the bacteria causing the infection.

Can the use of Septran DS 800mg/160mg Tablet cause nausea and vomiting?

Yes, the use of Septran DS 800mg/160mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

Are there any specific contraindications associated with the use of Septran DS 800mg/160mg Tablet?

Septran DS 800mg/160mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. It is also avoided in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia caused due to folate deficiency. The medicine is also harmful for pediatric patients less than 2 months of age and for patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

Can I stop taking Septran DS 800mg/160mg Tablet when my symptoms are relieved?

No, do not stop taking Septran DS 800mg/160mg Tablet and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

What is the recommended storage condition for Septran DS 800mg/160mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop taking Septran DS 800mg/160mg Tablet when I feel better?

No, do not stop taking Septran DS 800mg/160mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

What if I miss my dose?

Take Septran DS 800mg/160mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

What if I don't get better after using Septran DS 800mg/160mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

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Related lab tests

Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sulfamethoxazole and trimethoprim. [Accessed 10 Apr. 2019] (online) Available from:
Sulfamethoxazole and trimethoprim. Philadelphia, PA: AR Scientific, INC; 2013. [Accessed 10 Apr. 2019] (online) Available from:
Sulfamethoxazole and trimethoprim. Greenville, SC: PAI Pharma; 2025. [Accessed 08 Nov. 2025] (online). Available from:

Marketer details

Name: RV LIFESCIENCES LIMITED

Address: Plot No. H-19, MIDC, Waluj, Chhatrapati Sambhajinagar - 431133, Maharashtra State, India

Country of origin: India
Expires on or after: September, 2027

A licensed vendor partner from your nearest location will deliver Septran DS 800mg/160mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India