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20 Aug 2019 | 04:33 PM (IST)
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S-Ppi-L Capsule SR



S-Ppi-L Capsule SR is a combination of two medicines which is effective in treating gastroesophageal reflux disease (acid reflux). This prescription medicine reduces excess acid production in the stomach. It also prevents the reflux of stomach acid into the food pipe.

S-Ppi-L Capsule SR is to be taken in the dose and duration advised by your doctor. For better absorption of the medicine, take it in an empty stomach. A high dose or overdose may have harmful effects on the body. Always consult your doctor if you are suffering from any severe stomach, liver, or kidney disease.

This medication is generally well tolerated with very minimal side effects. Before taking the medicine, inform your doctor if you are pregnant, breastfeeding, or taking any other medicines of any other health condition or disease. You must stop this medication and consult your doctor in case you encounter any allergic reaction such as skin rash, swelling, and itching.

S-Ppi-L Capsule SR side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal upset
  • Stomach pain
  • Headache
  • Flatulence
  • Sleepiness

How to use S-Ppi-L Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. S-Ppi-L Capsule SR is to be taken empty stomach.
Take it preferably 30 minutes before food.

How S-Ppi-L Capsule SR works

S-Ppi-L Capsule SR is a combination of two medicines: Levosulpiride and Esomeprazole. Levosulpiride is a prokinetic which works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe). Esomeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and ulcers.

S-Ppi-L Capsule SR related warnings

It is unsafe to consume alcohol with S-Ppi-L Capsule SR
S-Ppi-L Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Information regarding the use of S-Ppi-L Capsule SR during lactation is not available. Please consult your doctor.
S-Ppi-L Capsule SR may cause side effects which could affect your ability to drive.
S-Ppi-L Capsule SR may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
There is limited information available on the use of S-Ppi-L Capsule SR in patients with kidney disease. Please consult your doctor.
However, limited data suggest a cautious use of this medicine in these patients.
S-Ppi-L Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of S-Ppi-L Capsule SR may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
S-Ppi-L Capsule SR
₹6.5/Capsule SR
Sompraz L Capsule SR
Sun Pharmaceutical Industries Ltd
₹21.3/Capsule SR
228% costlier
Raciper Plus Capsule SR
Sun Pharmaceutical Industries Ltd
₹19.8/Capsule SR
205% costlier
₹22.61/Capsule SR
248% costlier
Esogress-L Capsule SR
La Renon Healthcare Pvt Ltd
₹20.3/Capsule SR
212% costlier
Esofine-LS Capsule SR
Macleods Pharmaceuticals Pvt Ltd
₹17.6/Capsule SR
171% costlier

Expert Advice

  • It is a well-tolerated medicine and provides relief for a long time.
  • Take it one hour before the meal, preferably in the morning.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Do not consume alcohol while taking S-Ppi-L Capsule SR as it can increase the risk of stomach damage.
  • Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take S-Ppi-L Capsule SR for longer than prescribed.

Patient Concerns

Questions Related to S-Ppi-L

No eating food that's whay she become wik & wik
Dr. Gopal Samdani
Child Specialist
Talk to your pediatrician about your concerns. If it feels like more than typical ?picky eating? or it causes you stress in any way, insist on more help. If you don?t get an answer that feels comfortable to you, get a second opinion or even a thirdFor example, kids with chronic acid reflux or GERD quickly learn not to eat, because it hurtsFeeding your child is emotional: It?s about nurturing, bonding, love and responsibility as a parent. When feeding is challenging, it?s stressful and it impacts the entire family on a daily basis.I?ll say it again, it takes time That?s because your and his team will be doing a lot of clinical examination to learn what factors are impacting your child?s resistance to eating. Then, those elements need to be resolved one at a time.YOU are the most important part of the feeding team. You spend the most time with your child, know your child and family best and know what feels right.
I have acidity and acid reflux problem long for time I am taking PPI long time but last two years I am taking rabiprazol and levosulpride every third day or whenever reqiredit safe for me i feel ok when Take can i take when i feel acidity or acid refluxhow long can i use rebiprazol and levosulpride it is safe or not
Dr. Sunil Sekhri
Diabetes Specialist
if you are using it for a long duration get yourself assessed in clinic every 3 months
Do you have any questions related to S-Ppi-L Capsule SR?

User Feedback


Q. What are the instructions for storage and disposal of S-Ppi-L?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is the best time to take S-Ppi-L?

Take S-Ppi-L exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.

Q. What are the contraindications associated with the use of S-Ppi-L?

The use of S-Ppi-L should be avoided in patients with known allergy to any of the components or excipients of this medicine.

Q. Can the use of S-Ppi-L cause dizziness?

Yes, the use of S-Ppi-L can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Q. Does the use of S-Ppi-L lead to increased risk of fractures?

Several studies in adults suggest that treatment with S-Ppi-L may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was increased in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Levosulpiride. Limassol, Cyprus: Medochemie Ltd.; 2015. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. Esomerprazole. [Accessed 12 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Levosulpiride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. Esomerprazole. Barnstaple, Devon: Accord-UK Ltd.; 2013 [revised 7 May 2018]. [Accessed 12 Apr. 2019] (online) Available from:External Link
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