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Rupakast Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Rupakast Tablet is a combination medicine used in the treatment of allergy symptoms such as runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness.
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₹127 MRP ₹137.818% off 
 
 
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Rupakast Tablet is currently sold out
Same composition alternative:
Smarti-M Tablet
₹184₹199.03
Available alternative from Zydus Cadila
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Rupakast Tablet
Rupakast Tablet
strip of 10 tablets
₹127
₹137.81
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Same composition
Smarti-M Tablet
Smarti-M Tablet
strip of 10 tablets
Rupatadine (10mg) + Montelukast (10mg)
by Zydus Cadila
Get by Tomorrow
₹184
₹15.6 per tablet

₹156

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General Information

Contains

Rupatadine (10mg)+ Montelukast (10mg)

Marketer

Gurgrace Pharmaceuticals

Storage

Store below 30°C
The content is shown in English
Rupakast Tablet image
Rupakast Tablet image

Product introduction

Rupakast Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, dryness in mouth, diarrhea, skin rash, flu-like symptoms, headache, fatigue, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before you start taking this medicine it is important to inform your doctor if you are suffering from liver or kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Rupakast Tablet

  • Sneezing and runny nose due to allergies

Benefits of Rupakast Tablet

Sneezing and runny nose due to allergies
Rupakast Tablet is used to treat an itchy, stuffy or runny nose, sneezing, or other symptoms caused by seasonal hay fever (allergic rhinitis). It works by reducing certain substances in the body called histamines that are responsible for the allergic symptoms. It also reduces swelling inside the nose and thus decreases symptoms such as stuffy nose. This helps in easy breathing and makes you feel better.

Side effects of Rupakast Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rupakast
  • Nausea
  • Vomiting
  • Dryness in mouth
  • Diarrhea
  • Skin rash
  • Flu-like symptoms
  • Sleepiness
  • Headache
  • Fatigue
  • Dizziness
  • Weakness

How to use Rupakast Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rupakast Tablet may be taken with or without food.

How Rupakast Tablet works

Rupakast Tablet is a combination of two medicines: Rupatadine and Montelukast, which treats sneezing and runny nose caused due to allergies. Rupatadine is an antiallergic which blocks the action a chemical messenger (histamine) responsible for runny nose, watery eyes and sneezing. Montelukast is a leukotriene antagonist. It works by blocking the action of another chemical messenger (leukotriene). This reduces inflammation (swelling) in the airways and nose, and improves symptoms.

All substitutes for Rupakast Tablet

For information purposes only. Consult a doctor before taking any medicine.

Smarti-M Tablet

by Zydus Cadila
₹18.4/tablet
45% costlier
<h3 class=bodySemiBold>Smarti-M Tablet</h3>

Quick tips

  • You have been prescribed Rupakast Tablet to help relieve symptoms of allergy such as runny nose, sneezing, watery eyes, and cough.
  • Be cautious while driving or doing anything that requires concentration as Rupakast Tablet can cause dizziness and sleepiness.
  • Do not drink alcohol while taking Rupakast Tablet as it may cause increased sleepiness.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Stop taking Rupakast Tablet at least three days before taking an allergy test as it can affect the test results.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Rupakast Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Rupakast Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Rupakast Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Rupakast Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Rupakast Tablet in patients with kidney disease. Please consult your doctor.
Because of the limited information, use of Rupakast Tablet is not recommended in patients with kidney disease.
Liver

Liver

CAUTION
Rupakast Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Limited information is available on the use of Rupakast Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Frequently asked questions

Rupakast Tablet is used in the treatment of allergy symptoms such as a runny nose, stuffy nose, sneezing, watery eyes, and congestion or stuffiness.
People should not take Rupakast Tablet if they are allergic to any ingredient present in it, have severe liver problems, or take certain antifungals or antibiotics. Always consult your doctor before starting it.
Rupakast Tablet can be taken with some other medicines that treat allergy, but always inform your doctor about all medicines and supplements to avoid harmful interactions.
Serious effects of Rupakast Tablet are rare, but can include severe allergic reaction (rash, swelling, trouble breathing), abnormal thoughts or mood changes, palpitations, or persistent severe headache. If these occur, get medical help immediately.
Yes, sleepiness and dizziness may occur with Rupakast Tablet use. Avoid driving or using machines until you know how the medicine affects you.
Rupakast Tablet is generally safe for kids over 12 years, but always use it under a pediatrician's advice for younger children.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

References

  1. Montelukast sodium. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 04 Jan. 2018]. [Accessed 19 Apr. 2019] (online) Available from:
  2. Montelukast sodium. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1998 [revised Nov. 2014]. [Accessed 19 Apr. 2019] (online) Available from:
  3. Rupatadine. Petersfield, Hampshire: Aspire Pharma Ltd.; 2007 [revised 5 Dec. 2018]. [Accessed 19 Aprl. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gurgrace Pharmaceuticals
Address: SCO-5, 3rd Floor, Maheshpur, Near Indian Palace, Sector-21, Panchkula-134112

Vendor Details

Country of origin: India

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