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Rupatadine + Montelukast

Written By Dr. Sakshi JainReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Rupatadine + Montelukast Uses

Rupatadine+Montelukast is used in the treatment of sneezing and runny nose due to allergies.

How Rupatadine + Montelukast works

Rupatadine + Montelukast is a combination of two medicines: Rupatadine and Montelukast, which treats sneezing and runny nose caused due to allergies. Rupatadine is an antiallergic which blocks the action a chemical messenger (histamine) responsible for runny nose, watery eyes and sneezing. Montelukast is a leukotriene antagonist. It works by blocking the action of another chemical messenger (leukotriene). This reduces inflammation (swelling) in the airways and nose, and improves symptoms.

Common side effects of Rupatadine + Montelukast

Dryness in mouth, Diarrhea, Sleepiness, Headache, Fatigue, Dizziness, Upper respiratory tract infection, Fever, Abdominal pain
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Expert advice for Rupatadine + Montelukast

  • You have been prescribed Rupatadine + Montelukast to help relieve symptoms of allergy such as runny nose, sneezing, watery eyes, and cough.
  • Be cautious while driving or doing anything that requires concentration as Rupatadine + Montelukast can cause dizziness and sleepiness.
  • Do not drink alcohol while taking Rupatadine + Montelukast as it may cause increased sleepiness.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Stop taking Rupatadine + Montelukast at least three days before taking an allergy test as it can affect the test results.