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Ropclav 375 Tablet is an antibiotic that helps your body fight infections caused by bacteria. It treats infections of the lungs (e.g., pneumonia), the ear, the nasal sinus, the urinary tract, the skin, and the soft tissue. It will not work for viral infections such as the common cold.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 05 May 2026 | 05:53 PM (IST)
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General Information

Contains

Amoxycillin (250mg)+ Clavulanic Acid (125mg)

Marketer

Snu Biocare

Storage

Store below 30°C
The content is shown in English
Ropclav 375 Tablet image
Ropclav 375 Tablet image

Product introduction

Ropclav 375 Tablet is best taken with a meal to reduce the chance of a stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back or worsen.

The most common side effects of this medicine include vomiting, nausea, and diarrhea. These are usually mild but let your doctor know if they bother you or will not go away.

Before taking it, let your doctor know if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know about all other medicines you are taking as they may affect, or be affected by, this medicine. This medicine is generally regarded as safe to use during pregnancy and breastfeeding if prescribed by a doctor.

Uses of Ropclav Tablet

  • Treatment of Bacterial infections : These include respiratory tract infections (pneumonia, bronchitis), sinus infections (sinusitis), ear infections (otitis media), skin infections (cellulitis), bone and joint infections (osteomyelitis), and dental infections (dental abscess).

Benefits of Ropclav Tablet

Treatment of Bacterial infections
Bacterial infections can affect different parts of the body, such as the ear, sinus, throat, lungs, urinary tract, skin, teeth, joints, and bones. Ropclav 375 Tablet is an antibiotic that works by killing the bacteria causing the infection. This helps relieve symptoms, clear the infection, and prevent it from spreading or worsening. Complete the full prescribed course to ensure effective treatment and reduce the risk of resistance.

Side effects of Ropclav Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ropclav
  • Mucocutaneous candidiasis
  • Nausea
  • Vomiting
  • Diarrhea

How to use Ropclav Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ropclav 375 Tablet should be taken with or after food.

How Ropclav Tablet works

Ropclav 375 Tablet is a combination of two medicines: Amoxycillin and Clavulanic Acid. Amoxycillin is an antibiotic. It works by preventing the formation of the bacterial protective covering, which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor that reduces resistance and enhances the activity of Amoxycillin against bacteria.

All substitutes for Ropclav 375 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Amoxyclav 375 Tablet

by Abbott
₹17.7/tablet
24% costlier
<h3 class=bodySemiBold>Amoxyclav 375 Tablet</h3>

Omniclav 375 Tablet

by Cipla Ltd
₹16.08/tablet
13% costlier
<h3 class=bodySemiBold>Omniclav 375 Tablet</h3>

Moxikind-CV 375 Tablet

by Mankind Pharma Ltd
₹16.2/tablet
14% costlier
<h3 class=bodySemiBold>Moxikind-CV 375 Tablet</h3>

Clavam 375 Tablet

by Alkem Laboratories Ltd
₹20.3/tablet
43% costlier
<h3 class=bodySemiBold>Clavam 375 Tablet</h3>

Moxclav 375 Tablet

by Sun Pharmaceutical Industries Ltd
₹24.9/tablet
75% costlier
<h3 class=bodySemiBold>Moxclav 375 Tablet</h3>

Quick tips

  • Take Ropclav 375 Tablet, preferably with food, to avoid stomach upset.
  • Stick to simple meals, avoid fatty or spicy food, and drink plenty of water while taking this medicine.
  • Diarrhea may occur as a side effect. Taking probiotics along with this medicine may help.
  • Seek medical advice if diarrhea becomes severe or persistent, or if you notice bloody stools or develop abdominal cramps.
  • Stop taking Ropclav 375 Tablet and seek urgent medical attention if you develop a rash, itching, swelling of the face or throat, or difficulty breathing.
  • Do not use leftover medicine to treat any future infection. Always consult your doctor before taking any antibiotic.
  • Inform your doctor if you have kidney or liver disease before taking Ropclav 375 Tablet.
  • Complete the full course of treatment and do not stop it early, even if you start feeling better.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ropclav 375 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ropclav 375 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Ropclav 375 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Ropclav 375 Tablet may cause side effects that could affect your ability to drive.
Ropclav 375 Tablet may cause side effects such as allergic reactions, dizziness, or fits that may make you unfit to drive.
Kidney

Kidney

CAUTION
Ropclav 375 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of this medicine is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Ropclav 375 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is recommended while you are taking this medicine

Frequently asked questions

Ropclav 375 Tablet is an oral antibacterial combination of amoxicillin and clavulanic acid. It is used to treat a wide range of bacterial infections. It is commonly prescribed to treat infections such as ear infections (otitis media), sinus infections (bacterial rhinosinusitis), respiratory infections (pneumonia, bronchitis), and skin and soft tissue infections (cellulitis, abscesses).
Since Ropclav 375 Tablet is a penicillin-type antibiotic, individuals with a known penicillin allergy may be at higher risk of an allergic reaction. Patients who are allergic to penicillin or who have had a previous allergic reaction to Ropclav 375 Tablet should not use it.
Ropclav 375 Tablet should be used with caution in patients with liver disease or a history of jaundice. Dose adjustment may be needed. Your doctor will decide whether to prescribe this medicine after evaluating your condition, often with liver function tests. Always take it only after consulting your doctor.
As per the most recent evidence, Ropclav 375 Tablet does not interfere with hormonal birth control. However, talk to your doctor if you have any concerns. They can help you feel confident and protected. Antibiotics such as Ropclav 375 Tablet can cause nausea, vomiting, and diarrhea. If you vomit within two hours of taking the birth control pills, or if you have had diarrhea for 24 hours or more, your birth control pills may be ineffective. You may need to use an additional barrier method (such as condoms) in such cases.
No. It is very important to complete the full course of treatment, even if you start feeling better before finishing it. Feeling better does not necessarily mean that all the bacteria causing your infection have been eliminated. Stopping antibiotic treatment early may cause the symptoms to recur or make the bacteria resistant to the antibiotic.
Yes, diarrhea or loose motions is amongst the most commonly reported side effects of Ropclav 375 Tablet. In most cases, this is mild and resolves once the antibiotic course is complete. If you develop severe diarrhea, bloody stools, or abdominal cramping, or if symptoms persist or worsen, inform your doctor immediately.
No. Ropclav 375 Tablet is an antibiotic and works only against bacterial infections. Viruses cause the common cold and influenza (flu). Antibiotics are not effective against them. If you have a cold or flu, supportive care such as rest, staying hydrated, and using home remedies like saline gargles or steam inhalation may help with recovery.
Ropclav 375 Tablet begins to work against bacterial infections within hours of taking it. However, it may take 24 to 48 hours to notice improvement in your symptoms. If you do not notice any improvement, or if your symptoms worsen at any point, contact your doctor. This may indicate that the bacteria causing the infection are resistant to this antibiotic or that a different treatment is needed.
Special care is needed when Ropclav 375 Tablet is given to older adults, particularly those with reduced kidney function (renal impairment). The kidneys primarily clear Ropclav 375 Tablet from the body, so if they are not functioning well, the drug can build up in the body and increase the risk of side effects. Dose adjustment may be required based on kidney function.
Ropclav 375 Tablet fights infections caused by bacteria, specifically those that produce enzymes called beta-lactamases. These enzymes are a common mechanism by which bacteria defend themselves against antibiotics. Clavulanic acid blocks these enzymes, allowing amoxicillin to kill the bacteria effectively. This medicine is active against a broad range of bacteria, including both gram-positive and gram-negative types. Common bacteria it targets include Streptococcus pneumoniae (a cause of pneumonia and ear infections), Haemophilus influenzae (associated with respiratory and ear infections), and Moraxella catarrhalis (common in sinus and chest infections).

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

  1. Amoxicillin/clavulanate potassium. Research Triangle Park, North Carolina: GlaxoSmithKline. [Accessed 25 Jan. 2019] (online) Available from:
  2. Amoxicillin and clavulanic acid. Mayenne, France: Glaxo Wellcome Production; 2017. [Accessed 01 Feb. 2019] (online) Available from:
  3. Amoxicillin trihydrate and potassium clavulanate [EMC SmPC]. London, UK: GlaxoSmithKline UK; 2025. [Accessed 02 Jul. 2025] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Snu Biocare
Address: SCF 373, First Floor Motor Market, Manimajra, Chandigarh, India - 160041

Vendor Details

Country of origin: India

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