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Rofeb 25mg Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 06 Feb 2026 | 05:04 PM (IST)
Rofeb 25mg Tablet is a pain-relieving medicine. It helps relieve pain and reduces swelling, pain, and redness in various joint conditions such as osteoarthritis and rheumatoid arthritis. It is also used for the treatment of migraine and menstrual pain.
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₹22 MRP ₹24.059% off 
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General Information

Contains

Rofecoxib (25mg)

Marketer

Aristo Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Rofeb 25mg Tablet image
Rofeb 25mg Tablet image

Product introduction

Rofeb 25mg Tablet can be taken with or without food. The dose depends on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor and should not take more or use it for longer than recommended.

The most common side effects of this medicine include abdominal pain, upper respiratory infection, diarrhea, heartburn, nausea, and headache. These are not usually serious but if you are worried, ask your doctor about ways of reducing or preventing them.

You should not take this medicine if you have had a recent heart attack. Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine. Consumption of alcohol can increase the risk of getting an ulcer or bleeding.

Uses of Rofeb Tablet

Benefits of Rofeb Tablet

Pain relief
Rofeb 25mg Tablet helps to relieve pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis, migraine, menstrual pain, and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Rofeb Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rofeb
  • Abdominal pain
  • Upper respiratory tract infection
  • Nausea
  • Headache
  • Heartburn

How to use Rofeb Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rofeb 25mg Tablet may be taken with or without food.

How Rofeb Tablet works

Rofeb 25mg Tablet is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).

Quick tips

  • Rofeb 25mg Tablet helps relieve pain and inflammation.
  • It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
  • Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
  • Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
  • During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
  • Do not take Rofeb 25mg Tablet if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Rofeb 25mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Rofeb 25mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Rofeb 25mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CAUTION
Rofeb 25mg Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Rofeb 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Rofeb 25mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Rofeb 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Rofeb 25mg Tablet is not recommended in patients with moderate to severe liver disease.

Frequently asked questions

Yes, Rofeb 25mg Tablet is a pain killer and a prescription medicine that is used to relieve signs and symptoms of arthritis, acute pain in adults, and painful menstrual cycles.

Fact Box

Chemical Class

Stilbenes

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's -Selective COX-2 Inhibitors

References

  1. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 992.
  2. Sciencedirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  3. Sciencedirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  4. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India

Vendor Details

Country of origin: India

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