Overview

Uses of Rifa I-6 Tablet

Rifa I-6 Tablet is used in the treatment of tuberculosis.

Rifa I-6 Tablet side effects

Common
  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Teary eyes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice

How to use Rifa I-6 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifa I-6 Tablet is to be taken empty stomach.
Avoid Rifa I-6 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Rifa I-6 Tablet works

Rifa I-6 Tablet is a combination of three medicines: Isoniazid, vitamin B6 (pyridoxine) and rifampicin. Isoniazid prevents the TB bacteria from forming their own protective covering, while rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.

Rifa I-6 Tablet related warnings

Alcohol
CAUTION
Rifa I-6 Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Pregnancy
WEIGH RISKS VS BENEFITS
Rifa I-6 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Rifa I-6 Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
Rifa I-6 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rifa I-6 Tablet may not be needed in these patients. Please consult your doctor.
Liver
Rifa I-6 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Rifa I-6 Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

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Information last updated by Dr. Varun Gupta, MD Pharmacology on 14th Jun 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Concept Pharmaceuticals Ltd. 501 Jaisingh Business Center, 119, Sahar Road, Andheri (East) Mumbai - 400 099 India.
NOT FOR SALE
We do not facilitate sale of this product at present