Side Effects of RF HE are Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Increased liver enzymes, Jaundice, Visual impairment, Increased uric acid level in blood, Gout, Peripheral neuropathy (tingling and numbness of feet and hand).
How to use RF HE Kit
Take this medicine in the dose and duration as advised by your doctor. Check the label before use. RF HE Kit is to be taken empty stomach. Avoid RF HE Kit with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
RF HE Kit is a combination of three medicines: Rifampicin, isoniazid and ethambutol which treat tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.
In Depth Information on RF HE Kit
RF HE Kit related warnings
Special precautions for RF HE Kit
RF HE Kit may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
RF HE Kit may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
RF HE Kit is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well. RF HE Kit occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
RF HE Kit should be used with caution in patients with kidney disease. Dose adjustment of RF HE Kit may be needed. Please consult your doctor. Kidney function tests are advisable before the start of this medicine.
RF HE Kit should be used with caution in patients with liver disease. Dose adjustment of RF HE Kit may be needed. Please consult your doctor.
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Take the RF HE exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
Q. Can the use of RF HE make birth control pills ineffective?
Yes, RF HE can make birth control pills less effective. Ask the doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking RF HE.
Q. Is tuberculosis a curable disease?
Yes, tuberculosis (TB) is a curable disease and usually with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side-effects.
Q. What are the instructions for the storage and disposal of RF HE?
Keep this medicine in the packet or container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Q. Can the use of RF HE cause discoloration of the urine?
Yes, RF HE contain Rifampicin. It causes temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown colour). This side effect is usually not harmful. However, discolouration of urine can be a sign of liver damage. Call your doctor if you have discolouration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).
Q. Can I discontinue RF HE if I feel well?
No, do not discontinue RF HE.Take the proper course of a drug that has been prescribed for you even if you begin to feel better. If you stop taking RF HE then your infection may become worse, may become difficult to treat and it may result in drug-resistant TB i.e drugs you were taking may no longer work for Tuberculosis.
Q. Can RF HE cause visual impairment?
RF HE contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.