Side Effects of RF 4 are Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice, Increased uric acid level in blood, Visual impairment.
How to use RF 4 Kit
Take this medicine in the dose and duration as advised by your doctor. Check the label before use. RF 4 Kit is to be taken empty stomach. Avoid RF 4 Kit with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
RF 4 Kit is a combination of four medicines: Isoniazid, rifampicin, ethambutol and pyrazinamide which treat tuberculosis. Isoniazid works by preventing the TB bacteria from forming their own protective covering, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide, on the other hand work by slowing the growth of these bacteria.
In Depth Information on RF 4 Kit
RF 4 Kit related warnings
Special precautions for RF 4 Kit
RF 4 Kit may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
RF 4 Kit may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
RF 4 Kit is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
Do not drive unless you are feeling well. RF 4 Kit occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
RF 4 Kit should be used with caution in patients with kidney disease. Dose adjustment of RF 4 Kit may be needed. Please consult your doctor. Kidney function tests are advisable before the start of this medicine.
RF 4 Kit should be used with caution in patients with liver disease. Dose adjustment of RF 4 Kit may be needed. Please consult your doctor. Regular monitoring of liver function tests is advised before and after the start of the treatment.
User Submitted Feedback For RF 4 Kit
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Increased liver enzymes
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Q. Can the use of RF 4 cause discoloration of the urine?
Yes, RF 4 contain Rifampicin. It causes temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown colour). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).
Q. Can RF 4 cause visual impairment?
RF 4 contain ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Q. Can I discontinue RF 4 if I feel well?
No, do not discontinue RF 4.Take the proper course of a drug that has been prescribed for you even if you begin to feel better. if you stop taking RF 4 then your infection may become worse, may become difficult to treat and it may result in drug-resistant TB (drugs you are taking may no longer work).
Q. Can I take oral contraceptive pills while taking RF 4?
No, RF 4 can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking RF 4.
Q. What are the instructions for storage and disposal of RF 4?
Keep this medicine in the container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Q. How to take RF 4?
Take RF 4 empty stomach, at leas one hour before and two hours after a meal and with full glass of water.
Q. Can I drink alcohol while taking RF 4?
No, avoid drinking alcohol while taking RF 4. Drinking alcohol will increase the risk of hepatitis caused by RF 4 because of isoniazid.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 12th Apr 2018.