Rextin-CR Plus Tablet ER
Prescription RequiredProduct introduction
Rextin-CR Plus Tablet ER is a prescription medicine used to treat depression. It is a combination medicine that works by increasing the level of chemical messengers in the brain that improve mood. It also calms the brain by decreasing the abnormal and excessive activity of the nerve cells.
Rextin-CR Plus Tablet ER can be taken with or without food. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor, as it has habit-forming potential. Try to never skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly, as it may result in withdrawal symptoms.
Some common side effects of this medicine include nausea, vomiting, confusion, memory impairment, low sexual desire, and delayed ejaculation. It may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression, as this medicine may cause suicidal thoughts.
Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Uses of Rextin-CR Plus Tablet ER
Benefits of Rextin-CR Plus Tablet ER
In Depression
Rextin-CR Plus Tablet ER works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.
Side effects of Rextin-CR Plus Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rextin-CR Plus
- Nausea
- Vomiting
- Diarrhea
- Confusion
- Memory impairment
- Uncoordinated body movements
- Drowsiness
- Tiredness
- Anorgasmia (decreased orgasm)
- Low sexual desire
- Delayed ejaculation
- Sleepiness
- Dryness in mouth
- Constipation
How to use Rextin-CR Plus Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rextin-CR Plus Tablet ER may be taken with or without food.
How Rextin-CR Plus Tablet ER works
Rextin-CR Plus Tablet ER is a combination of two medicines, paroxetine and clonazepam, which have mood-enhancing and anxiety-lowering effects. Paroxetine is a selective serotonin reuptake inhibitor (SSRI), which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) that increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Rextin-CR Plus Tablet ER
Pregnancy
UNSAFE
Rextin-CR Plus Tablet ER is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Rextin-CR Plus Tablet ER may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Rextin-CR Plus Tablet ER may cause side effects that could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Rextin-CR Plus Tablet ER is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Use of Rextin-CR Plus Tablet ER can cause excessive sleepiness in patients with end stage kidney disease.
Use of Rextin-CR Plus Tablet ER can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Rextin-CR Plus Tablet ER should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Rextin-CR Plus Tablet ER?
If you miss a dose of Rextin-CR Plus Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Take Rextin-CR Plus Tablet ER with a snack or just after eating breakfast, as this will help to reduce the likelihood of you feeling sick as a side effect.
- It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two if you feel it is not helping.
- Avoid taking antacids 2 hours before or after taking Rextin-CR Plus Tablet ER, as they make it harder for your body to absorb the medicine.
- Inform your doctor immediately if you have thoughts about harming yourself or ending your life.
- If you have diabetes, you will be asked to monitor your blood glucose level regularly, as this medicine may affect the levels of sugar in your blood.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Fact Box
Habit Forming
Yes
Therapeutic Class
NEURO CNS
Patient concerns
FAQs
Are there any important warnings associated with the use of Rextin-CR Plus Tablet ER?
Rextin-CR Plus Tablet ER may increase suicidal thoughts or actions in some patients in the first few months of the treatment. Patients with mood or behavioral disorders have a high risk of suicidal thoughts and actions. You should pay close attention and report to your doctor any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.
Can I stop taking Rextin-CR Plus Tablet ER when my symptoms are relieved?
No, you should continue taking Rextin-CR Plus Tablet ER even if you feel well. If you stop Rextin-CR Plus Tablet ER suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.
How to manage weight gain associated with the use of Rextin-CR Plus Tablet ER?
Some reports suggest that the use of Rextin-CR Plus Tablet ER can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than to lose weight.
Can the use of Rextin-CR Plus Tablet ER cause sleepiness?
Yes, Rextin-CR Plus Tablet ER can make you feel sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities until you know how this medicine affects you.
Can the use of Rextin-CR Plus Tablet ER affect my sex life?
The use of Rextin-CR Plus Tablet ER can affect the sexual life of both men and women. Different sexual problems can occur due to Rextin-CR Plus Tablet ER, like decreased sexual desire, erectile dysfunction (inability to develop or maintain an erection during sexual activity), and inability to reach orgasm. It can also cause a decrease in satisfaction and discomfort during intercourse. If you experience these problems, discuss them with your doctor.
Can I drink alcohol while taking Rextin-CR Plus Tablet ER?
No, do not drink alcohol while taking Rextin-CR Plus Tablet ER. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Rextin-CR Plus Tablet ER.
How long does Rextin-CR Plus Tablet ER take to work?
Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Rextin-CR Plus Tablet ER, although some people may start to feel better sooner. When taking Rextin-CR Plus Tablet ER, it is important to give it time to work.
What are the instructions for the storage and disposal of Rextin-CR Plus Tablet ER?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Paroxetine. Miami, Florida: Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 23 Apr. 2019] (online) Available from:
- Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:
- Paroxetine. Roswell, Georgia: Sebela Pharmaceuticals Inc.; 2023. [Accessed 03 Apr. 2025] (online) Available from:
- Paroxetine hydrochloride [Product Information]. East Windsor, NJ: Aurobindo pharma USA Inc.; 2025. [Accessed 03 Apr. 2025] (online) Available from:
- Parpxetin and clonazepam. Mumbai, Maharashtra: Alkem Laboratories Limited.; [Accessed 03 Apr. 2025] (online) Available from:
Marketer details
Name: Mabril Healthcare Pvt Ltd
Address: C- 36, Kendriya Vihar Jankipuram Ext, Sector-6, Lucknow-22
Country of origin: India
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