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Composition for REBREX EYE DROP

Tobramycin(0.3%w/v),Benzalkonium Chloride(0.005%w/v)

food interaction for REBREX EYE DROP

alcohol interaction for REBREX EYE DROP

pregnancy interaction for REBREX EYE DROP

lactation interaction for REBREX EYE DROP

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Rebrex eye drop is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Tobramycin is used as an injection for treating bacterial infections of the skin, heart, stomach, brain, spinal cord, lungs, and urinary tract (bladder and kidneys). It is also used in the treatment of cystic fibrosis. In the form of eye-drops, it can be used to treat eye infections.

How it works

Tobramycin is an aminoglycoside antibiotic produced by bacteria Streptomyces tenebrarius. It acts by blocking protein synthesis in bacterial cell, causing disruption of the cell envelope and eventual cell death.

Common side effects

Nausea, Noisy breathing, Oral fungal infection, Rash, Thoracic pain, Chest pain, Chest tightness, Shortness of breath, Cough, Dizziness, Dry eye, Gastric pain, Fungal infection, Headache, Hearing loss, Coughing up blood, Liver toxicity, Hoarseness of voice, Increased saliva production, Loss of appetite, Mouth ulcer, Tongue ulcer, Ringing in ear, Sore throat, Weakness, Increased sputum production
Benzalkonium Chloride(0.005%w/v)


Bladder irrigation, ear, eye, nose and throat irrigation, gingivitis, perodontal diseases, preoperative disinfection of unbroken skin, stomatitis, thrush, tonsillitis, urethral irrigation.

How it works

The mode of action of benzalkonium chloride appears to be associated with the effect on the cytoplasmic membrane, which controls cell permeability.

Common side effects

Paralysis of respiratory muscle, Allergic contact dermatitis, Apprehension, Collapse, Coma, Convulsion, Cyanosis (bluish discoloration of the skin), Death, Shortness of breath, Muscle weakness, Restlessness, Vomiting


No substitutes found

Expert advice for REBREX EYE DROP

  • Do not use tobramycin if you are allergic to it or any other component in the formulation.
  • Driving and using machinery should be avoided in cases where tobramycin usage causes dizziness or eye drops cause blurring of vision.
  • Do not mix or dilute your tobramycin with any other medicine in your nebulizer.
  • If you are taking several different treatments for cystic fibrosis, you should take them in the following order: bronchodilator (e.g. salbutamol), then chest physiotherapy, followed by inhaled medicines, and then tobramycin.
  • Do not use contact lenses when on treatment with tobramycin eye drops.
  • If you are using more than one eye drop, keep a gap of at least 5-10 minutes between two different eye drops.
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: neuromuscular disorders such as parkinsonism, myasthenia gravis (characterized by movement disorders and/or muscle weakness); coughing up blood in your sputum; kidney problem.
  • Inform your doctor if you have ever experienced in the past: ringing in ears, any other problems with hearing, dizziness while taking tobramycin.

Frequently asked questions for REBREX EYE DROP


Q. Is tobramycin a sulfa drug or penicillin antibiotic?
No. Tobramycin is an aminoglycoside antibiotic used to treat Pseudomonas infections and other serious infections in patients (6 years and older) with cystic fibrosis.
Q. Does tobramycin treat styes, Pseudomonas, pink eye, staphylococcus and methicillin resistant staphylococcus aureus (MRSA)?
Tobramycin/dexamethasone combination can be used to cure pink eye and styes, which are superficial eye and eyelid infections. Tobramycin treats Pseudomonas infections however it is not drug of choice in the treatment of staphylococcus or MRSA.
Q. Is tobramycin safe for infants?
No. Due to high propensity for kidney and internal ear damage, tobramycin shouldn’t be given to infants.
Q. Is tobramycin over the counter?
No. Tobramycin belongs to schedule H and can be obtained only on production of valid prescription.
Q. Is tobramycin the same as ofloxacin?
No. Tobramycin and Ofloxacin belong to different class of antibiotics, and are used to treat different sets of infections.

Benzalkonium Chloride

Q. Is benzalkonium chloride the same as rubbing alcohol?
No. Benzalkonium chloride is not as same as rubbing alcohol.
Q. Is benzalkonium chloride antifungal?
Yes, benzalkonium chloride is known to be antifungal to some extent. 
Q. Does benzalkonium chloride kill viruses?
No. Benzalkonium does not kill viruses.
Q. Is benzalkonium chloride bleach?
No. Benzalkonium chloride is not bleach. 
Q. Does benzalkonium chloride kill MRSA (Methicillin-resistant Staphylococcus aureus)/ staph (Staphylococcus Aureus)?
Yes, higher concentrations of benzalkonium chloride can kill MRSA / staph present on the skin.
Q. Does benzalkonium chloride work for cold sores?
Yes. Benzalkonium chloride is effective for treatment of cold sores.


Content on this page was last updated on 02 July, 2014, by Dr. Varun Gupta (MD Pharmacology)