Raparen 1mg Injection
Prescription Required
Product introduction
Raparen 1mg Injection is used for prevention of organ rejection in transplant patients. It works by regulating the body’s immune response following organ transplant. This helps your body to accept the new organ as if it were your own.
Raparen 1mg Injection is a prescription medicine that must be administered by a doctor or a nurse in a hospital or a clinical setting. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.
The common side effects of this medicine include headache, increased heart rate, high blood pressure, abdominal pain, nausea, diarrhea, constipation, rash, joint pain, increased risk of infections, decreased blood cells, and decreased potassium level in blood. If any of the side effects persist or get worse, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, and swelling.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.
Uses of Raparen Injection
Benefits of Raparen Injection
In Prevention of organ rejection in transplant patients
Raparen 1mg Injection is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Raparen Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Raparen
- Decreased blood cells (red cells, white cells, and platelets)
- Increased risk of infection
- Nausea
- Protein in urine
- Upset stomach
- Abdominal pain
- Constipation
- Decreased potassium level in blood
- Diarrhea
- Headache
- High blood pressure
- Increased heart rate
- Rash
- Joint pain
How to use Raparen Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Raparen Injection works
Raparen 1mg Injection is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Raparen 1mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Raparen 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Raparen 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Raparen 1mg Injection may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Raparen 1mg Injection is safe to use in patients with kidney disease. No dose adjustment of Raparen 1mg Injection is recommended.
Liver
CAUTION
Raparen 1mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Raparen 1mg Injection may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
What if you forget to take Raparen Injection?
If you miss a dose of Raparen 1mg Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Raparen 1mg Injection is used with other medications to prevent organ transplant rejection.
- Avoid certain vaccines during treatment as the vaccination may be less effective when taking Raparen 1mg Injection. Consult your doctor.
- Use effective methods of contraception during the treatment and for 12 weeks after Raparen 1mg Injection has been stopped.
- Limit the exposure to sunlight by covering your skin with clothing and using sunscreen with a high SPF because of the increased risk for skin cancer, when taking Raparen 1mg Injection.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- mTOR inhibitors
Interaction with drugs
Taking Raparen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Long-term concurrent use may increase the risk of certain brain infections.
Do not consume Natalizumab with Sirolimus.
Concomitant use may cause lethal infections.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Sirolimus or for up to 6
Enzalutamide may reduce blood levels of Sirolimus.
Do not consume Sirolimus with Enzalutamide. If concurrent use is essential, your doctor may monitor your treatment and adjust th
Carbamazepine may reduce blood levels of Sirolimus.
Do not consume Sirolimus with Carbamazepine. If concurrent use is essential, your doctor may monitor your treatment and adjust
Sirolimus may increase the metabolism of Isavuconazole.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1267-68.
- Sirolimus [EMC SmPC]. Bruxelles, Belgium: Pfizer Europe MA EEIG; 2001 [revised 13 Mar. 2011]. [Accessed 30 Jan. 2020] (online) Available from:
- Sirolimus [FDA Label]. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2011. [Accessed 30 Jan. 2020] (online) Available from:
- Sirolimus [Package Leaflet]. Co. Kildare, Ireland: Pfizer Ireland Pharmaceuticals; 2019. [Accessed 30 Jan. 2020] (online) Available from:
- Sirolimus [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2020. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: La Renon Healthcare Pvt Ltd
Address: Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Country of origin: India
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NOT FOR SALE
We do not facilitate sale of this product at present
