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Rantrio-ESR Capsule is a prescription medicine used to treat gastroesophageal reflux disease (acid reflux). It helps relieve symptoms such as heartburn, stomach pain, or irritation. It also reduces acid production and promotes easy gas passage to reduce stomach discomfort.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 28 Apr 2026 | 05:30 PM (IST)
₹106 MRP ₹117.1910% off 
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Esomer D 30mg/40mg Capsule SR
₹178₹196.88
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Rantrio-ESR Capsule
Rantrio-ESR Capsule
strip of 10 capsule sr
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Same composition
Esomer D 30mg/40mg Capsule SR
Esomer D 30mg/40mg Capsule SR
strip of 10 capsule sr
by Glenmark Pharmaceuticals Ltd
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₹178
₹16.4 per unit

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Rantrio-ESR Capsule image
Rantrio-ESR Capsule image
Rantrio-ESR Capsule image

Product introduction

Rantrio-ESR Capsule is best taken on an empty stomach. Take it in the dose and duration advised by the doctor. Continue taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects of Rantrio-ESR Capsule include diarrhea, flatulence, stomach pain, dryness in the mouth, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also tell your doctor if you have severe liver disease so that your doctor can prescribe a suitable dose for you. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food, or chocolate can help you get better results.

Benefits of Rantrio-E Capsule SR

Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a condition in which stomach acid flows back into the food pipe (esophagus), causing symptoms like heartburn and irritation. Rantrio-ESR Capsule reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Rantrio-E Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rantrio-E
  • Diarrhea
  • Flatulence
  • Stomach pain
  • Dryness in mouth
  • Headache
  • Nausea

How to use Rantrio-E Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rantrio-ESR Capsule is to be taken on an empty stomach.

How Rantrio-E Capsule SR works

Rantrio-ESR Capsule is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic that works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn.

Quick tips

  • Take Rantrio-ESR Capsule on an empty stomach 30 minutes to 1 hour before the meal.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Long-term use can cause weak bones and a deficiency of minerals such as magnesium.
  • Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rantrio-ESR Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Rantrio-ESR Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Rantrio-ESR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Rantrio-ESR Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Rantrio-ESR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Rantrio-ESR Capsule is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Yes, Rantrio-ESR Capsule is safe for most of the patients. However, in some patients, it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in the mouth, dizziness, headache, and other uncommon and rare side effects. Inform your doctor if you experience any persistent problems while taking this medicine.
It is best to take Rantrio-ESR Capsule before the first meal of the day or on an empty stomach.
The use of Rantrio-ESR Capsule is considered to be harmful for patients with a known hypersensitivity to esomeprazole and domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Yes, the use of Rantrio-ESR Capsule can cause dry mouth. Dryness of the mouth occurs due to domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. If you have a dry mouth, try to use alcohol-free mouthwash, as its use can increase the risk of tooth decay.
Yes, the use of Rantrio-ESR Capsule can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequent urination and dark-colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Strio Healthcare
Address: 212, Sahajanand Estate, Behind Lalji-Mulji Transport, Sarkhej, Ahmedabad-382210, Gujarat

Vendor Details

Country of origin: India
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