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Rame H 5mg/12.5mg Tablet is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 30 Jul 2026 | 01:04 AM (IST)
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Rame H 5mg/12.5mg Tablet
Rame H 5mg/12.5mg Tablet
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Rame H 5mg/12.5mg Tablet image
Rame H 5mg/12.5mg Tablet image

Product introduction

Rame H 5mg/12.5mg Tablet is taken with or without food, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

Nausea, indigestion, taste change, and diarrhea are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Let your doctor know about cough or throat irritation that does not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness may occur due to low blood pressure but this gets better with time.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function and the levels of salts such as potassium checked regularly to make sure that this medicine is working properly.

Uses of Rame H Tablet

Benefits of Rame H Tablet

Hypertension (high blood pressure)
Rame H 5mg/12.5mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Rame H Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rame H
  • Nausea
  • Indigestion
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Dizziness
  • Weakness
  • Glucose intolerance
  • Increased uric acid level in blood
  • Increased blood lipid level
  • Electrolyte imbalance
  • Cough
  • Decreased blood pressure
  • Tickling
  • Nutritional disorders
  • Worsening of diabetes
  • Hypotension (low blood pressure)
  • Fatigue
  • Bronchitis (inflammation of the airways)
  • Nonproductive cough
  • Sinus inflammation
  • Breathlessness
  • Increased potassium level in blood
  • Muscle pain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Chest pain

How to use Rame H Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rame H 5mg/12.5mg Tablet may be taken with or without food.

How Rame H Tablet works

Rame H 5mg/12.5mg Tablet is a combination of two medicines:

Quick tips

  • You have been prescribed Rame H 5mg/12.5mg Tablet for the treatment of high blood pressure.
  • It also lowers your risk of stroke and heart attack.
  • Take it in the morning with breakfast, to avoid getting up at night to urinate.
  • Rame H 5mg/12.5mg Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform you doctor about any cough, or throat irritation that doesn't go away.
  • Rame H 5mg/12.5mg Tablet may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
  • Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
  • Do not take Rame H 5mg/12.5mg Tablet if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Rame H 5mg/12.5mg Tablet.
Pregnancy

Pregnancy

UNSAFE
Rame H 5mg/12.5mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Rame H 5mg/12.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Rame H 5mg/12.5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Rame H 5mg/12.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of blood pressure is recommended for dose adjustment.
Liver

Liver

CAUTION
Rame H 5mg/12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Please consult your doctor. It should not be used in severe liver disease.
All

Frequently asked questions

Rame H 5mg/12.5mg Tablet is used to treat high blood pressure. Ramipril in Rame H 5mg/12.5mg Tablet helps relax blood vessels, while hydrochlorothiazide in Rame H 5mg/12.5mg Tablet helps remove excess fluid from the body, both working together to lower blood pressure.
Individuals should not take Rame H 5mg/12.5mg Tablet if they are allergic to ramipril, hydrochlorothiazide, other ACE inhibitors, or sulfonamide-derived medicines, or if they have severe kidney problems, an inability to urinate, or a history of swelling of the face or throat (angioedema) caused by ACE inhibitors.
Yes, Rame H 5mg/12.5mg Tablet can cause angioedema, which is serious swelling of the face, lips, tongue, or throat. This can happen at any time during treatment and needs urgent medical attention.
Yes, Rame H 5mg/12.5mg Tablet can reduce kidney function, especially in people with existing kidney disease, dehydration, or heart failure. Your doctor may order regular kidney function tests while you are on this medicine.
Yes, Rame H 5mg/12.5mg Tablet can lower potassium and sodium levels. Blood tests are needed to check electrolyte balance during treatment.
People with severe liver disease should not take Rame H 5mg/12.5mg Tablet, and those with milder liver problems should be closely monitored, as it can affect electrolyte and fluid balance.
Yes, Rame H 5mg/12.5mg Tablet can cause a sudden drop in blood pressure, especially after the first dose or if you are dehydrated, on a low-salt diet, or taking other blood pressure medicines.
Yes, Rame H 5mg/12.5mg Tablet may raise uric acid levels, which may trigger gout in some people.
Rame H 5mg/12.5mg Tablet can increase blood sugar levels, so people with diabetes may need adjustments to their treatment and closer monitoring.
Rame H 5mg/12.5mg Tablet should be used with caution in people with heart problems, such as heart failure, as it can affect blood pressure and kidney function.
During Rame H 5mg/12.5mg Tablet treatment, regular monitoring helps track blood pressure, kidney function, and electrolyte levels to ensure the medicine is working safely and effectively.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Genetic Pharma
Address: 1098, G J Patel Estate, Bajwa, Vadodara - 391310, Near Government Hospital

Vendor Details

Country of origin: India
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