Rafdonac-XL Tablet is a pain-relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
Take Rafdonac-XL Tablet with food to reduce an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
There is limited data on the side effects of Rafdonac-XL Tablet. Let your doctor know if you experience any symptoms while taking Rafdonac-XL Tablet. They may be able to suggest ways to treat or manage the side effects.
Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment.
Rafdonac-XL Tablet is a combination of medicines that is used for short term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache, periods pain and pain due to arthritis too. Take Rafdonac-XL Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Rafdonac-XL Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rafdonac-XL
Limited data available
How to use Rafdonac-XL Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rafdonac-XL Tablet should be taken with or after food.
How Rafdonac-XL Tablet works
Rafdonac-XL Tablet is a combination of three medicines: Diclofenac, Paracetamol and Trypsin Chymotrypsin which relieve pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes that break down proteins into smaller fragments, thereby making them available for absorption into the blood. They increase blood supply in the affected area and reduce swelling.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rafdonac-XL Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Rafdonac-XL Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Rafdonac-XL Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Rafdonac-XL Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Rafdonac-XL Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Rafdonac-XL Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed. However, the use of Rafdonac-XL Tablet is not recommended in patients with severe liver disease and active liver disease.
What if you forget to take Rafdonac-XL Tablet?
If you miss a dose of Rafdonac-XL Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
To reduce the risk of stomach irritation, consider taking this medicine with food or a glass of milk.
Stick to the prescribed dose and do not exceed the recommended dosage, as an overdose may lead to side effects like stomach pain or liver damage.
Drink plenty of water and stay hydrated to help your body process the medication and reduce the risk of kidney issues.
Watch for symptoms like stomach discomfort, nausea, or allergic reactions. If any serious side effects occur, consult your doctor immediately.
Fact Box
Habit Forming
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Therapeutic Class
PAIN ANALGESICS
Patient concerns
I have SHT in last 10 years.I already take somany medicine but I can't get a good results.In my heart rate around 160 range.I feel chest tightness little pain also.I can't walk properly.Because that time I feel heavy palpitation and I hearing my heart beat sound in my ears.In my blood pressure shows on 170/100.Now I took these medicines.1 TRIOLMEZEST 40 Once daily morning.2 CALAPTIN-SR 120 once daily night.But still I not better now.Doctor said me after one month i need a Holter Monitoring test.I have no other physical problems.Please give me a feedback
Dr. Nabajit Talukdar
Cardiology
Add minipress xl 7.5 mg twice dailyHow is renal function test
Blakishbrown spots on both lower legs and feet about5 years no pain and swelling I have border line sugar taking cetanil m for bp pl suggest cause and treatment
Dr. Souvik Sardar
Dermatology
Use momate xl cream mixed with aquasoft cream in 1 : 1 ratio - apply twice daily for 4wks
Since long time I am taking Tab. Libotryp XL 25. Also taking Amlopin M 50 & LTK 50 bec I m BP Patient. Without taking Libotryp xl I can't sleep. I know it is dangerous for long period. Please guide me is there any option?
Dr. Venkatraju Kalidindi
Psychiatry
Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling. please try curd rice in dinner Curd Dhahi" "yogurt" has good qualities it acts as digestive and get good sleep."
Medicines are prescribed after clinical examination. This portal is to guide you regarding your problems and clarify doubts. Please see a psychiatrist for treatment.
Rafdonac-XL Tablet is a combination of four medicines: diclofenac, paracetamol, trypsin, and chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that cause pain and swelling.
Can I get addicted to Rafdonac-XL Tablet?
No, there are no reports of any patient getting addicted to Rafdonac-XL Tablet.
Can I stop taking Rafdonac-XL Tablet when my pain is relieved?
Rafdonac-XL Tablet is usually used for the short term and can be discontinued when your pain is relieved. However, Rafdonac-XL Tablet should be continued if your doctor has advised you to do so.
Can the use of Rafdonac-XL Tablet cause damage to the kidneys?
Yes, long-term use of Rafdonac-XL Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. The use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage on long-term use. The use of painkillers is not recommended for patients with underlying kidney disease.
Can the use of Rafdonac-XL Tablet cause damage to liver?
Rafdonac-XL Tablet contains paracetamol. This medicine is known to cause harm to the liver, especially in doses above the recommended level. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin, or eyes.
How long will Rafdonac-XL Tablet take to act?
It may take about an hour to see the initial benefits of pain relief after taking Rafdonac-XL Tablet.
Will a higher than the recommended dose of Rafdonac-XL Tablet be more effective?
No, taking a higher-than-recommended dose may not be more effective; rather, it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for reevaluation.
Are there any specific contraindications associated with the use of Rafdonac-XL Tablet?
The use of Rafdonac-XL Tablet is considered to be harmful for patients with known allergies to any of the components or excipients of Rafdonac-XL Tablet. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or patients with active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
What are the instructions for storage and disposal of Rafdonac-XL Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
National Health Service. Paracetamol for adults. [Accessed 06 Feb. 2020] (online) Available from:
Fibovil: Trypsin Chymotrypsin + Diclofenac Potassium + Paracetamol [Product Information]. [Accessed 10 Mar. 2025] (online) Available from:
Manufacturer details
Name: Logos pharma
Address: Maissa Tibba, Nalagarh Solan,H.P-174101
Marketer details
Name: Human Biolife India Pvt Ltd
Address: H.O :315, Industrial Area Phase-III, Panchkula (Haryana)-134109