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LYSoflam Tablet is a pain-relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 21 Jan 2026 | 03:59 PM (IST)
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General Information

Contains

Diclofenac (50mg)+ Paracetamol (325mg)+ Trypsin Chymotrypsin (50000AU)

Marketer

Cachet Pharmaceuticals Pvt Ltd

Storage

Store below 25°C
The content is shown in English
LYSoflam Tablet image
LYSoflam Tablet image
LYSoflam Tablet image
LYSoflam Tablet image
LYSoflam Tablet image
LYSoflam Tablet image
LYSoflam Tablet image

Product introduction

Take LYSoflam Tablet with food to reduce an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.


There is limited data on the side effects of LYSoflam Tablet. Let your doctor know if you experience any symptoms while taking LYSoflam Tablet. They may be able to suggest ways to treat or manage the side effects.


Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment.

Uses of LYSoflam Tablet

Benefits of LYSoflam Tablet

Pain relief
LYSoflam Tablet is a combination of medicines that is used for short term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache, periods pain and pain due to arthritis too.
Take LYSoflam Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of LYSoflam Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of LYSoflam
  • Limited data available

How to use LYSoflam Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. LYSoflam Tablet should be taken with or after food.

How LYSoflam Tablet works

LYSoflam Tablet is a combination of three medicines: Diclofenac, Paracetamol and Trypsin Chymotrypsin which relieve pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes that break down proteins into smaller fragments, thereby making them available for absorption into the blood. They increase blood supply in the affected area and reduce swelling.

All substitutes for LYSoflam Tablet

For information purposes only. Consult a doctor before taking any medicine.

Chymoflam Tablet

by Aglowmed Limited
₹13.7/tablet
5% cheaper
<h3 class=bodySemiBold>Chymoflam Tablet</h3>

Chyzime D 50mg/325mg Tablet

by Syndicate Life Sciences Pvt Ltd
₹14.1/tablet
2% cheaper
<h3 class=bodySemiBold>Chyzime D 50mg/325mg Tablet</h3>

Aimfoheal DP Tablet

by Aim Four Life Line Private Limited
₹9.34/tablet
35% cheaper
<h3 class=bodySemiBold>Aimfoheal DP Tablet</h3>

Triptogesic Tablet

by Neuborn Life Science
₹9.43/tablet
35% cheaper
<h3 class=bodySemiBold>Triptogesic Tablet</h3>

Acetoflam 50mg/325mg Tablet

by Asthev Healthcare Private Limited
₹9.85/tablet
32% cheaper
<h3 class=bodySemiBold>Acetoflam 50mg/325mg Tablet</h3>

Quick tips

  • To reduce the risk of stomach irritation, consider taking this medicine with food or a glass of milk.
  • Stick to the prescribed dose and do not exceed the recommended dosage, as an overdose may lead to side effects like stomach pain or liver damage.
  • Drink plenty of water and stay hydrated to help your body process the medication and reduce the risk of kidney issues.
  • Watch for symptoms like stomach discomfort, nausea, or allergic reactions. If any serious side effects occur, consult your doctor immediately.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with LYSoflam Tablet
Pregnancy

Pregnancy

UNSAFE
LYSoflam Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
LYSoflam Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
LYSoflam Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
LYSoflam Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

UNSAFE
LYSoflam Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of LYSoflam Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

LYSoflam Tablet is a combination of four medicines: diclofenac, paracetamol, trypsin, and chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that cause pain and swelling.
No, there are no reports of any patient getting addicted to LYSoflam Tablet.
LYSoflam Tablet is usually used for the short term and can be discontinued when your pain is relieved. However, LYSoflam Tablet should be continued if your doctor has advised you to do so.
Yes, long-term use of LYSoflam Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. The use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage on long-term use. The use of painkillers is not recommended for patients with underlying kidney disease.
LYSoflam Tablet contains paracetamol. This medicine is known to cause harm to the liver, especially in doses above the recommended level. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin, or eyes.
It may take about an hour to see the initial benefits of pain relief after taking LYSoflam Tablet.
No, taking a higher-than-recommended dose may not be more effective; rather, it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for reevaluation.
The use of LYSoflam Tablet is considered to be harmful for patients with known allergies to any of the components or excipients of LYSoflam Tablet. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or patients with active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. National Health Service. Paracetamol for adults. [Accessed 06 Feb. 2020] (online) Available from:
  2. Fibovil: Trypsin Chymotrypsin + Diclofenac Potassium + Paracetamol [Product Information]. [Accessed 10 Mar. 2025] (online) Available from:
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User feedback

Twice A Day
65%
Once A Day
21%
Thrice A Day
14%
Pain relief
65%
Others
15%
Dental pain
12%
Headache
4%
Pain during menstruation
3%
Average
43%
Poor
29%
Excellent
28%
No Side Effect
66%
Vomiting
10%
Diarrhea
5%
Stomach pain
2%
Nausea
2%
With food
91%
With or without food
6%
Empty stomach
3%
Average
55%
Expensive
24%
Not Expensive
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cachet Pharmaceuticals Pvt Ltd
Address: Exhibition Road, P.S. Gandhi Maidan, Patna – 800001

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver LYSoflam Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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