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Rabium Plus Capsule PR is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity, such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)
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General Information

Contains

Rabeprazole (20mg)+ Itopride (150mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image
Rabium Plus Capsule PR image

Product introduction

Rabium Plus Capsule PR is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your healthcare team know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects are stomach pain, diarrhea, constipation, headache, flatulence, weakness, and increased saliva production. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine, as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food, or chocolate can help you to get better results.


Before you start taking this medicine, it is important to inform your doctor if you are suffering from liver disease. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Rabium Plus Capsule PR

Side effects of Rabium Plus Capsule PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rabium Plus
  • Diarrhea
  • Headache
  • Dizziness
  • Vomiting
  • Abdominal pain
  • Nausea
  • Weakness
  • Flatulence
  • Back pain

How to use Rabium Plus Capsule PR

Use it as advised by your doctor or check the label for directions before use. Rabium Plus Capsule PR is to be taken on an empty stomach.

How Rabium Plus Capsule PR works

Rabium Plus Capsule PR is a combination of two medicines: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn. Itopride is a prokinetic that works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

All substitutes for Rabium Plus Capsule PR

For information purposes only. Consult a doctor before taking any medicine.

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Quick tips

  • You have been prescribed Rabium Plus Capsule PR for the treatment of acidity and heartburn.
  • Take it one hour before the meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Rabium Plus Capsule PR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Rabium Plus Capsule PR during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Rabium Plus Capsule PR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Rabium Plus Capsule PR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Rabium Plus Capsule PR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Rabium Plus Capsule PR should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Rabium Plus Capsule PR is prescribed for the treatment of gastroesophageal reflux disease (GERD) and peptic ulcer disease. Rabeprazole in Rabium Plus Capsule PR helps reduce excess stomach acid, while itopride in Rabium Plus Capsule PR improves stomach movement, helping relieve symptoms like heartburn, indigestion, and bloating.
People with severe liver problems, certain allergies to the ingredients of the medicine, or those taking medicines that interact with rabeprazole or itopride should avoid taking Rabium Plus Capsule PR.
Although they are rare, serious side effects of Rabium Plus Capsule PR may include severe allergic reactions, skin rashes, liver problems, and changes in liver function tests. Seek urgent medical attention if you notice swelling, difficulty breathing, or severe skin changes.
Yes, symptom relief from Rabium Plus Capsule PR does not rule out the possibility of serious conditions such as stomach cancer. Your doctor may recommend further tests if symptoms persist.
There is limited information on the safety of Rabium Plus Capsule PR in kidney disease. Consult your doctor before starting treatment if you have kidney problems.
Long-term use of Rabium Plus Capsule PR may lead to changes in stomach cells, including rare growths, and low magnesium levels. Your doctor may monitor you if prolonged therapy is needed.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

References

  1. Rabeprazole Sodium and Itopride Hydrochloride [Summary of Product Characteristics]. Nairobi, Kenya: Zain Pharma Ltd.; 2023.
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User feedback

Once A Day
100%
Acidity
43%
Heartburn
43%
Others
14%
Excellent
52%
Average
33%
Poor
14%
No Side Effect
50%
Constipation
33%
Abdominal pain
17%
Empty stomach
60%
With food
40%
Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Rabium Plus Capsule PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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