RABEST D 30 MG/20 MG TABLET

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Composition FOR RABEST D

Domperidone(30mg),Rabeprazole(20mg)

food interaction for RABEST D

alcohol interaction for RABEST D

pregnancy interaction for RABEST D

lactation interaction for RABEST D

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
UNSAFE
Rabest d 30 mg/20 mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR RABEST D

Domperidone(30mg)

Uses

Domperidone is used in the treatment of vomiting.

How it works

Domperidone indirectly stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine.

Common side effects

Dry mouth.
Rabeprazole(20mg)

Uses

Rabeprazole is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

How it works

Rabeprazole lowers the acid production in the stomach.

Common side effects

Nausea, Abdominal pain, Constipation, Diarrhoea, Flatulence.

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Expert advice FOR RABEST D

  • Do not take Domperidone, if you are allergic to it or to any other content in the tablets.
  • Do not take the medicine, if you notice black, tarry stools (bowel motions) or blood in your stools, blockage or tear in the intestines or if you have a tumor of the pituitary gland (prolactinoma).
  • Do not take the drug, if you have moderate to severe liver disease, heart problems (irregular heart rate or heart failure) or abnormal salt levels in the blood.
  • Do not crush or chew the tablets, swallow them whole with a glass of water.
  • Do not take the drug if you intend to drive or operate heavy machinery as it may cause drowsiness.
  • Always take the tablets 15 to 30 minutes before meals and, if needed, before going to bed at night.
  • Consult your doctor, if you are above 60 years of age and taking domperidone for a long period of time.
  • Inform your doctor, if you are already taking medicines for fungal infections (ketoconazole) or antibiotics (e.g. gentamycin, erythromycin).

Frequently asked questions FOR RABEST D

Domperidone

Q. What is Domperidone used for?
Domperidone is used for the treatment of nausea (feeling sick) and vomiting as and when recommended by your doctor.
Q. Is domperidone an over the counter drug?
Domperidone is not an over the counter (OTC) medicine and it is not advisable to take it without a prescription.
Q. Does domperidone cause weight gain?
Weight gain has not been reported with the use of domperidone. If you notice any abnormal weight gain while using domperidone, please talk to your doctor.
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Q. Does domperidone raise the blood pressure?
The increase in blood pressure is generally not seen with the use of domperidone. But if you experience an increase in blood pressure while using domperidone, please consult your doctor.
Q. Can I take domperidone for morning sickness?
Domperidone is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness.
Q. How long can I take domperidone for breastfeeding?
Domperidone is not recommended if you are breastfeeding because it passes into breast milk and may affect your baby. Talk to your doctor as either you should not take this medicine or you should stop breastfeeding if you are asked to take it.
Q. Can I take domperidone with antibiotics?
The use of domperidone with antibiotics like erythromycin, levofloxacin, moxifloxacin, spiramycin, and some antifungals is not recommended. Please consult your doctor before using any antibiotics with domperidone.
Q. Can I take domperidone with lansoprazole?
Yes, domperidone can be taken with lansoprazole as no drug-drug interactions have been clinically seen when they are taken together. However, interactions may occur. Please consult your doctor before using the two medicines together.
Q. Can I take domperidone with doxycycline?
Yes, domperidone can be taken with doxycycline. No drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with doxycycline.
Q. Can I take domperidone with omeprazole?
Yes, domperidone can be taken with omeprazole. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor before using the two medicines together.
Q. Can I take domperidone with citalopram?
The use of domperidone with citalopram is not recommended as it may increase the underlying heart problems like prolonged QTc interval. Please consult your doctor before taking the two medicines together.
Q. Can I take domperidone with amitriptyline?
Yes, domperidone can be taken with amitriptyline. No drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with amitriptyline.
Q. Can I take domperidone with amoxicillin?
Yes, domperidone can be taken with amoxicillin. No drug-drug interactions have been reported. However, please consult your doctor before taking domperidone with amoxicillin.
Q. Can I take domperidone with paracetamol?
Yes, domperidone can be taken with paracetamol. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor.
Q. Can I take domperidone without food?
It is recommended to take domperidone tablets 15 - 30 minutes before meals.
Q. Can I take domperidone with tramadol?
Yes, domperidone can be taken with tramadol as no drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with tramadol.
Q. Is domperidone safe in pregnancy?
There is limited data on the use of domperidone in pregnant women. Therefore, domperidone should only be used during pregnancy when justified and recommended by the doctor.
Q. Is domperidone safe?
Yes. Domperidone is safe if used at prescribed doses for the prescribed duration as advised by the physician/ doctor.
Q. Is domperidone safe for babies?
Yes, domperidone is safe for use babies if used at prescribed doses and duration as advised by your doctor. Please consult your doctor before giving any medicine to your child.
Q. Is domperidone used for motion sickness?
Domperidone is indicated for use in motion sickness. Please consult your doctor before using domperidone for motion sickness as it must be used in the dose and duration as advised by your doctor.
Q. Is domperidone an antibiotic?
No, domperidone is not an antibiotic. Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick).
Q. Does domperidone cause drowsiness?
Drowsiness has been reported as one of the rare side effects with domperidone. Please talk to your doctor if you experience excessive drowsiness while taking domperidone.
Q. Does domperidone increase milk secretion?
Yes, domperidone can increase milk secretion also known as galactorrhea. This is an uncommon side effect of domperidone. Talk to your doctor if you are experiencing this side effect while taking this medicine.
Q. Does domperidone cause bloating (gas)?
Domperidone can cause some uncommon gastrointestinal side effects like regurgitation, appetite disorder, and heartburn, diarrhoea. However, bloating (gas) has not been reported as a side effect with domperidone.
Q. Does domperidone cause hair loss?
Domperidone has not been reported to cause hair loss. Please consult your doctor in case you experience excessive hair loss while taking domperidone.
Q. Does domperidone help constipation?
Domperidone is not indicated to treat constipation. Please talk to your doctor regarding its use.
Q. Does domperidone cause heart problems?
Domperidone may be associated with an increased risk of heartbeat problem and heart attack. This risk may be more likely in those over 60 years old or taking higher doses. The risk also increases when domperidone is given together with other medicines. Please share your medical history with your doctor if you are prescribed domperidone.
Q. Does domperidone cause constipation?
Yes, domperidone has been seen to cause constipation as a side effect.Consult your doctor if you experience excessive constipation while using domperidone.
Q. Does domperidone relieve bloating (gas)?
Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick). It is not indicated to treat bloating (gas). Please consult your doctor before using this medicine.
Q. Can I take Domperidone with rabeprazole?
Domperidone can be safely taken with Rabeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Rabeprazole

Q. Is rabeprazole an over the counter product?
No, rabeprazole is not an over the counter product, it is available when prescribed by a doctor.
Q. Is rabeprazole an antacid?
Rabeprazole is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.
Q. Does rabeprazole cause osteoporosis (thinning of bones)?
Yes, long term use of rabeprazole can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.
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Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with rabeprazole?
Rabeprazole can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Rabeprazole takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking rabeprazole as antacids can increase the pH of the stomach and decrease the action of Rabeprazole which requires a lower pH for its action.
Q. Does rabeprazole have addictive potential?
No, rabeprazole has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.
Q. Is rabeprazole safe?
Yes, rabeprazole is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does rabeprazole cause hair loss?
No, hair loss has not been reported as a side effect of rabeprazole. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.
Q. Does rabeprazole cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of rabeprazole. Although it would be mild to moderate in nature and transient.
Q. Does rabeprazole cause tinnitus (ringing in the ears)?
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of rabeprazole. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.
Q. Does rabeprazole cause weight gain?
Weight gain has been reported as a rare side effect of rabeprazole. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.
Q. Does rabeprazole expire?
Yes, like any other medicine, rabeprazole also expires. Always check the expiry date on the pack of the medicine before using it.
Q. Does rabeprazole cause constipation?
Constipation is a common side effect seen in patients using rabeprazole. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.
Q. Does rabeprazole cause high blood pressure?
Rabeprazole is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with rabeprazole includes nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does rabeprazole cause headache?
Headache is reported as one of the common side effects of rabeprazole. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking rabeprazole.
Q. Can I take rabeprazole with ranitidine?
Yes, esomeprazole can be taken with ranitidine. No drug-drug interactions or any harmful effects have been reported when they are used together. As esomeprazole do take some days to show its action, so, ranitidine is given to the patients to immediate relief.
Q. Can I take rabeprazole with ibuprofen?
Rabeprazole can be taken with ibuprofen. Rabeprazole is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take rabeprazole with paracetamol?
Rabeprazole can be taken with paracetamol. Rabeprazole is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. How is rabeprazole metabolized?
Rabeprazole is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of rabeprazole for a long time and a better suppression of stomach acid.
Q. Can rabeprazole be used for the treatment of throat infection?
No, rabeprazole is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.
Q. Why is rabeprazole used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with rabeprazole.
Q. Does rabeprazole play any role in treating ulcerative colitis?
Rabeprazole does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.
Q. Can rabeprazole be used for reflux esophagitis?
Yes, rabeprazole is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Rabeprazole decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.
Q. Is rabeprazole being used for treating weight loss?
No, rabeprazole is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.
Q. Is there any role of rabeprazole in treating hiatus hernia?
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Rabeprazole does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.
Q. Is rabeprazole better than omeprazole?
Rabeprazole and omeprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that rabeprazole provides better relief of the symptoms including the daytime pain of duodenal ulcers. The difference in response may also vary in different patients.
Q. Is rabeprazole better than pantoprazole?
Rabeprazole and pantoprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that rabeprazole is more effective in decreasing acid secretion compared to pantoprazole. The difference in response may also vary in different patients.
Q. Can rabeprazole be taken twice a day?
Yes, rabeprazole is taken two times a day when used for the treatment of stomach ulcers caused by Helicobacter pylori. It is given along with antibiotics and is to be taken for one week once in the morning and once in the evening. It is taken once a day for the treatment of heartburn, acidity, stomach and intestinal ulcers.
Q. Can I take rabeprazole with vitamin D?
Yes, vitamin D can be taken with rabeprazole. Vitamin D is generally advised to be taken as a supplement with rabeprazole as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.
Q. Why are rabeprazole tablets enteric coated?
Rabeprazole gets absorbed in the small intestine, so it must reach there in intact form for proper absorption. However, it gets easily degraded by the stomach acid. So, an enteric coating saves the tablet from stomach acid so that it can reach the small intestine in intact form. Enteric-coated tablets should not be broken or crushed before swallowing.
Q. How is rabeprazole different from esomeprazole?
Rabeprazole and esomeprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Both decrease acid production in the stomach and are seen to be almost equally effective and safe in many clinical research studies. However, the response may vary from patient to patient and depend on the dose.
Q. How is rabeprazole useful in the treatment of H. pylori?
Rabeprazole is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Q. How is rabeprazole different from ranitidine?
Both rabeprazole and ranitidine lower the amount of acid produced in the stomach. Rabeprazole is seen to be more effective in resolving heartburn in patients with gastroesophageal reflux disease (GERD). It rapidly heals stomach and duodenal ulcers and also prevents ulcers formation in patients who use nonsteroidal anti-inflammatory drugs (NSAIDs). However, the effect of these medicines may vary from patient to patient.
Q. Can I take rabeprazole with domperidone?
Rabeprazole can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Q. Can long term use of Rabeprazole cause magnesium deficiency?
Long-term use of Rabeprazole can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)