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Quadrajel Gel is a combination medicine used in the treatment of mouth ulcers. It promotes the healing of mouth ulcers by forming a protective coating over the mouth sores. It also blocks the transmission of pain signals to the brain to decrease the sensation of pain.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 May 2026 | 12:24 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 May 2026 | 12:24 PM (IST)
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30 gm Dental Gel
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General Information
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Product introduction
Quadrajel Gel should be used strictly as advised by your doctor. Use it in the dose and duration as directed by your doctor. You should not use more quantity or more often than prescribed by your doctor. This will not make it work any faster rather increase the chance of side effects.
Using of this medicine may cause some common side effects such as application site reactions (burning, irritation, itching, and redness), dryness in mouth, metallic taste, nausea, and staining of teeth. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same condition or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.
Using of this medicine may cause some common side effects such as application site reactions (burning, irritation, itching, and redness), dryness in mouth, metallic taste, nausea, and staining of teeth. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same condition or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.
Uses of Quadrajel Dental Gel
Benefits of Quadrajel Dental Gel
Treatment of Mouth ulcers
Mouth ulcers are small painful sores on inner lips, gums, tongue, roof of the mouth or throat that may interfere with eating, drinking and even talking. Quadrajel Gel blocks chemicals in our brain that are responsible for pain sensation and inflammation. Therefore it provides relief from pain, discomfort and symptoms of inflammation such as redness or swelling due to mouth ulcers. Quadrajel Gel also contains antimicrobial agents that kill the harmful bacteria and prevent any further infections. This makes it easier for you to go about your daily activities. Continue using it as advised by the doctor to get maximum benefit.
Mouth ulcers are small painful sores on inner lips, gums, tongue, roof of the mouth or throat that may interfere with eating, drinking and even talking. Quadrajel Gel blocks chemicals in our brain that are responsible for pain sensation and inflammation. Therefore it provides relief from pain, discomfort and symptoms of inflammation such as redness or swelling due to mouth ulcers. Quadrajel Gel also contains antimicrobial agents that kill the harmful bacteria and prevent any further infections. This makes it easier for you to go about your daily activities. Continue using it as advised by the doctor to get maximum benefit.
Side effects of Quadrajel Dental Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Quadrajel
- Application site reactions (burning, irritation, itching and redness)
- Dryness
- Metallic taste
- Nausea
- Staining of teeth
How to use Quadrajel Dental Gel
Check the label for directions before use. Gently apply the gel to the affected area inside your mouth. Refrain from eating or drinking immediately after applying the gel.
How Quadrajel Dental Gel works
Quadrajel Gel is a combination of three medicines: Lidocaine, Chlorhexidine Gluconate and Metronidazole, which treats mouth sores. Lidocaine is a local anesthetic which forms a protective coating over the mouth sores and blocks pain signals to further relieve pain. Chlorhexidine Gluconate is an antiseptic and disinfectant which effectively cleans out the ulcer surface to prevent infection. Metronidazole is an antibiotic which kills the bacteria and other microorganisms by damaging their DNA.
All substitutes for Quadrajel Gel
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Quadrajel Gel is used to treat painful mouth ulcers.
- Avoid eating and drinking immediately after applying Quadrajel Gel.
- Avoid putting dentures back in the mouth for half an hour after applying the gel in your mouth.
- Use a soft toothbrush after consulting your dentist.
- Avoid spicy foods, acidic fruit drinks, and very salty foods (such as crisps) which can make the pain and sting worse.
- Do not smoke while using Quadrajel Gel as it might cause some side effects.
- Consult your doctor if your pain does not improve after using this medication for 7-14 days, or if your symptoms get worse.
- Quadrajel Gel is used to treat painful mouth ulcers.
- Avoid eating and drinking immediately after applying Quadrajel Gel.
- Avoid putting dentures back in the mouth for half an hour after applying the gel in your mouth.
- Use a soft toothbrush after consulting your dentist.
- Avoid spicy foods, acidic fruit drinks, and very salty foods (such as crisps) which can make the pain and sting worse.
- Do not smoke while using Quadrajel Gel as it might cause some side effects.
- Consult your doctor if your pain does not improve after using this medication for 7-14 days, or if your symptoms get worse.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Quadrajel Gel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Quadrajel Gel may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Frequently asked questions
Yes, the use of Quadrajel Gel can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Fact Box
Habit Forming
No
Therapeutic Class
STOMATOLOGICALS
References
- Drasner K. Local Anesthetics. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 439-450.
- Catterall WA, Mackie K. Local Anesthetics. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 405-419.
- Sheppard D, Lampiris HW. Antifungals Agents. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 835-844.
- Phillips MA, Stanley, Jr SL. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1049-72.
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User feedback
Mouth ulcers
67%
Others
33%
Poor
33%
Average
33%
Excellent
33%
No Side Effect
100%
With or without food
50%
With food
50%
Average
100%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Fourrts India Laboratories Pvt Ltd
Address: Plot No.: 1, Fourrts Avenue, Annai Indira nagar, Okkiyam thoraipakkam, Chennai - 600 097
Address: Plot No.: 1, Fourrts Avenue, Annai Indira nagar, Okkiyam thoraipakkam, Chennai - 600 097
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Quadrajel Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Quadrajel Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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