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Metrohex Plus + Gel is a combination medicine used in the treatment of mouth ulcers. It promotes the healing of mouth ulcers by forming a protective coating over the mouth sores. It also blocks the transmission of pain signals to the brain to decrease the sensation of pain.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 09 Mar 2026 | 10:46 AM (IST)
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20 gm Dental Gel
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Metrohex Plus + Gel
Metrohex Plus + Gel
tube of 20 gm Dental Gel
₹5.0 per gm
₹118
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₹100

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₹1200
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by Dr Reddy's Laboratories Ltd
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Metrohex Plus + Gel image
Metrohex Plus + Gel image
Metrohex Plus + Gel image

Product introduction

Metrohex Plus + Gel should be used strictly as advised by your doctor. Use it in the dose and duration as directed by your doctor. You should not use more quantity or more often than prescribed by your doctor. This will not make it work any faster rather increase the chance of side effects.

Using of this medicine may cause some common side effects such as application site reactions (burning, irritation, itching, and redness), dryness in mouth, metallic taste, nausea, and staining of teeth. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same condition or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.

Uses of Metrohex Plus Dental Gel

Benefits of Metrohex Plus Dental Gel

Treatment of Mouth ulcers
Mouth ulcers are small painful sores on inner lips, gums, tongue, roof of the mouth or throat that may interfere with eating, drinking and even talking. Metrohex Plus + Gel blocks chemicals in our brain that are responsible for pain sensation and inflammation. Therefore it provides relief from pain, discomfort and symptoms of inflammation such as redness or swelling due to mouth ulcers. Metrohex Plus + Gel also contains antimicrobial agents that kill the harmful bacteria and prevent any further infections. This makes it easier for you to go about your daily activities. Continue using it as advised by the doctor to get maximum benefit.

Side effects of Metrohex Plus Dental Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metrohex Plus
  • Application site reactions (burning, irritation, itching and redness)
  • Dryness
  • Metallic taste
  • Nausea
  • Staining of teeth

How to use Metrohex Plus Dental Gel

Check the label for directions before use. Gently apply the gel to the affected area inside your mouth. Refrain from eating or drinking immediately after applying the gel.

How Metrohex Plus Dental Gel works

Metrohex Plus + Gel is a combination of three medicines: Lidocaine, Chlorhexidine Gluconate and Metronidazole, which treats mouth sores. Lidocaine is a local anesthetic which forms a protective coating over the mouth sores and blocks pain signals to further relieve pain. Chlorhexidine Gluconate is an antiseptic and disinfectant which effectively cleans out the ulcer surface to prevent infection. Metronidazole is an antibiotic which kills the bacteria and other microorganisms by damaging their DNA.

Quick tips

  • Metrohex Plus + Gel is used to treat painful mouth ulcers.
  • Avoid eating and drinking immediately after applying Metrohex Plus + Gel.
  • Avoid putting dentures back in the mouth for half an hour after applying the gel in your mouth.
  • Use a soft toothbrush after consulting your dentist.
  • Avoid spicy foods, acidic fruit drinks, and very salty foods (such as crisps) which can make the pain and sting worse.
  • Do not smoke while using Metrohex Plus + Gel as it might cause some side effects.
  • Consult your doctor if your pain does not improve after using this medication for 7-14 days, or if your symptoms get worse.
  • Metrohex Plus + Gel is used to treat painful mouth ulcers.
  • Avoid eating and drinking immediately after applying Metrohex Plus + Gel.
  • Avoid putting dentures back in the mouth for half an hour after applying the gel in your mouth.
  • Use a soft toothbrush after consulting your dentist.
  • Avoid spicy foods, acidic fruit drinks, and very salty foods (such as crisps) which can make the pain and sting worse.
  • Do not smoke while using Metrohex Plus + Gel as it might cause some side effects.
  • Consult your doctor if your pain does not improve after using this medication for 7-14 days, or if your symptoms get worse.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Metrohex Plus + Gel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Metrohex Plus + Gel may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Yes, the use of Metrohex Plus + Gel can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

STOMATOLOGICALS

References

  1. Drasner K. Local Anesthetics. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 439-450.
  2. Catterall WA, Mackie K. Local Anesthetics. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 405-419.
  3. Sheppard D, Lampiris HW. Antifungals Agents. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 835-844.
  4. Phillips MA, Stanley, Jr SL. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1049-72.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Metrohex Plus + Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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