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MD (Pharmacology), MBBS
Last updated on:
15 Jan 2019 | 02:45 PM (IST)
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Overview

Introduction

Pyrinate Tablet is a combination of three medicines. This prescription medicine manages the feeling of nausea or vomiting during pregnancy. It blocks signals to reach the brain that trigger the feeling of nausea and vomiting.

Pyrinate Tablet is to be taken in the dose and duration advised by your doctor. You can take it with or without food, preferably at a fixed time.

This medication may make you feel dizzy or sleepy, so do not drive or do anything that requires mental focus. This medicine is generally well tolerated by patients. However, it may cause side effects like nausea, dryness of mouth, and lightheadedness. Before taking the medicine always consult your doctor if you are pregnant, breastfeeding or if you are suffering from any severe stomach, liver, kidney disease, or any known disease. You must stop this medication and consult your doctor in case you encounter any allergic reactions such as skin rash, swelling, and itching.

Uses of Pyrinate Tablet

Pyrinate Tablet side effects

Common
  • Dryness in mouth
  • Constipation
  • Drowsiness
  • Lightheadedness

How to use Pyrinate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrinate Tablet is to be taken with food.

How Pyrinate Tablet works

Pyrinate Tablet is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic is also a form of vitamin B which provides essential nutrients.

Pyrinate Tablet related warnings

Alcohol
CAUTION
Caution is advised when consuming alcohol with Pyrinate Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Pyrinate Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Lactation
SAFE IF PRESCRIBED
Pyrinate Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Larger doses or prolonged use of Pyrinate Tablet may cause sleepiness and other effects in the baby
Driving
UNSAFE
Pyrinate Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pyrinate Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pyrinate Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pyrinate Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pyrinate Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pyrinate Tablet
₹2.12/Tablet
Doxinate Plus Tablet
Maneesh Pharmaceuticals Ltd
₹6.37/Tablet
201% costlier
Vomilast Tablet
Mankind Pharma Ltd
₹5/Tablet
136% costlier
Sysfol Plus Tablet
Systopic Laboratories Pvt Ltd
₹3.85/Tablet
82% costlier
Gleedox Tablet
Wockhardt Ltd
₹5.4/Tablet
155% costlier
Limefresh 10mg/10mg/2.5mg Tablet
Moraceae Pharmaceuticals Pvt Ltd
₹4.5/Tablet
112% costlier

Expert Advice

  • Pyrinate Tablet helps treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes. 
  • Take it on an empty stomach with a glass of water.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not take it with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents
  • Do not take Pyrinate Tablet while breastfeeding.

Patient Concerns

Questions Related to Pyrinate

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My wife is 13 week pregnent her docter change her tablet from mvista to doxynate plus me I know the reason is both tablet aee same. Docter asked to taje doxynate plus 2 tablet at bed time.please suggest.
Dr. Megha Tuli
Gynaecologist
Doxynate is tablet to stop vomiting dear. It is ok to take them at bed time. It is widely recommended to take for nausea and vomiting of pregnancy.
Vomiting and doses issue with metformin and other salt with istanet 500mg tablet! How to avoid vomiting and nausea
Dr. Ashwin Porwal
Diabetes Specialist
ask your doctor to change your medicine
arrow
Do you have any questions related to Pyrinate Tablet?

User Feedback


FAQs

Q. What are the instructions for storage and disposal of Pyrinate?

Keep this medicine in the container or the pack it came in, tightly closed. Store it at as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Pyrinate can cause increased side effects. If you are experiencing increased severity of nausea or vomiting, which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can the use of Pyrinate cause drowsiness or sleepiness?

Yes, one of the common side effects of Pyrinate is drowsiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking Pyrinate. Severe drowsiness can happen or it can become worse and cause falls or accidents.

Q. Can I breastfeed while taking Pyrinate?

No, it is not advisable to breastfeed while using Pyrinate. This medicine can pass into the breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.

Q. Can the use of Pyrinate cause dry mouth?

Yes, the use of Pyrinate can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.

Q. Can a pregnant woman take Pyrinate?

Yes, it is safe to take Pyrinate in pregnant women. In fact, this medicine is used to treat nausea and vomiting in pregnant women. It is mainly recommended to those women whose symptoms have not improved after changing their diet or using other non-medicine treatments.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Doxylamine succinate and pyridoxine hydrochloride. Blainville, Québec: Duchesnay Inc.; 1976 [revised Nov. 2016]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. DailyMed. Doxylamine succinate and pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Vitamin B6. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. DailyMed. Pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  5. Folic Acid. Maidenhead: Intrapharm Laboratories Limited; 2011 [revised 8 May 2018]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  6. Folic Acid. Whiddon Valley: Actavis UK Limited; 1987 [revised 01 Mar. 2019]. [Accessed 12 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Khasra No 410, Village Karondi, Roorkee-Deheradun Highway, ROORKEE 247667, Roorkee, Uttarakhand 247667
A licensed pharmacy from your nearest location will deliver Pyrinate Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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