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Prozine Plus 100 mg/2 mg Tablet


Overview

Introduction

Prozine Plus 100 mg/2 mg Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Prozine Plus 100 mg/2 mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Prozine Plus Tablet

Side effects of Prozine Plus Tablet

Common
  • Nausea
  • Constipation
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Increased prolactin level in blood
  • Dizziness
  • Blurred vision
  • Dryness in mouth
  • Nervousness

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Weight gain
    Try to eat a healthy balanced diet without increasing your portion sizes. Avoid processed meat or poultry and seafood. Eat small, frequent meals and eat slowly. Do not snack on foods that contain a lot of calories such as crisps, cakes, biscuits and sweets. If you feel hungry between meals, eat fruits and vegetables which have low calories. Avoid reaching for a sugary drink if you feel stressed. Fasting once a week can be an effective way to lose weight. Make sure you get enough sleep. With proper diet and lifestyle changes, you might not gain any weight or may gain only a small amount. Even then if it bothers you, ask your doctor if there are any alternative medicines that do not have this side effect.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Blurred vision
    You can consider washing your eyes with water. Avoid driving or using tools or machines if your vision is impaired. Do not take your next dose if your vision is still blurry. If it gets worse or does not improve, ask your doctor to recommend eye drops or talk about changing your medications.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Nervousness
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.

How to use Prozine Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prozine Plus 100 mg/2 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Prozine Plus Tablet works

Prozine Plus 100 mg/2 mg Tablet is a combination of two medicines: Chlorpromazine and Trihexyphenidyl/Benzhexol. Chlorpromazine is a typical antipsychotic. It works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl/Benzhexol is added to treat and prevent these side effects.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Prozine Plus 100 mg/2 mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Prozine Plus 100 mg/2 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Prozine Plus 100 mg/2 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If the Prozine Plus 100 mg/2 mg Tablet is given, monitor the baby for excessive sleepiness during breastfeeding.
Driving
UNSAFE
Prozine Plus 100 mg/2 mg Tablet may cause side effects which could affect your ability to drive.
Prozine Plus 100 mg/2 mg Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Prozine Plus 100 mg/2 mg Tablet in patients with kidney disease. Please consult your doctor.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Prozine Plus 100 mg/2 mg Tablet in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Prozine Plus 100 mg/2 mg Tablet
₹1.49/Tablet
₹1.5/Tablet
1% costlier
Relitil Plus 100 mg/2 mg Tablet
Reliance Formulation Pvt Ltd
₹1.8/Tablet
21% costlier
Trichlor Plus 100 mg/2 mg Tablet
Tripada Biotec Pvt Ltd
₹1.84/Tablet
24% costlier
₹1.99/Tablet
34% costlier
₹2.59/Tablet
74% costlier

Quick Tips

  • Prozine Plus 100 mg/2 mg Tablet is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug induced abnormal movements.
  • Be cautious while driving or doing anything that requires concentration as Prozine Plus 100 mg/2 mg Tablet can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication as it may lower its efficacy.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Prozine Plus 100 mg/2 mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Patient Concerns

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Parkinson in Right hand and Right leg since last 10 Years using below Medline but not getting permanent solution What I should do ? Now feeling Lack of Confidence & Memory 1-AMANTREL 100 MG CAPSULE 2-SYNDOPA PLUS TABLET 3-PRAMIROL SR 0.52MG TABLET 4-PACITANE 2 MG TABLET
Dr. Vikas Sharma
Neurology
Tab censpram 5 mg daily
I am using climaxing p.if I change Citico plus 500 mg/400 mg
Dr. Vikas Sharma
Neurology
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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chlorpromazine. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2005 [revised 14 Dec. 2016]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Chlorpromazine. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Trihexyphenidyl. [Accessed 23 Apr. 2019] (online) Available from:External Link
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