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PROVATE PLUS CREAM

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 10 Apr 2026 | 10:55 AM (IST)
PROVATE PLUS CREAM belongs to a group of medicines called steroids. It is used to treat allergic skin conditions. It relieves inflammation, itching, and redness of various skin disorders. It works by preventing the release of substances in the body that cause inflammation.
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General Information

The content is shown in English
PROVATE PLUS CREAM image
PROVATE PLUS CREAM image

Product introduction

PROVATE PLUS CREAM is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water if you accidentally get it in these areas. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor.

Use of this medicine may cause a burning sensation, itching, irritation, redness, and pain at the site of application. These are temporary and usually go away with time. However, if they persist or worsen, let your doctor know.

Benefits of Provate Plus Cream

Treatment of Allergic conditions
PROVATE PLUS CREAM is used to treat many different inflammatories and allergic conditions including arthritis, lupus, psoriasis, ulcerative colitis, and conditions that affect the skin, blood, eyes, lungs, stomach, and nervous system. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.

This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Treatment of Allergic skin conditions
PROVATE PLUS CREAM is effective in treating allergic skin conditions with inflammation and itching such as eczema, psoriasis, and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin. When used correctly it is a safe and effective treatment. In treating psoriasis, it reduces the scaly, itchy patches which may develop on the elbows, knees, scalp and other parts of the body. In treating eczema and dermatitis, it reduces the redness, rash, pain, or itchiness caused by your skin’s reaction to an irritant. It thus improves your self-esteem and confidence as your appearance changes.

You should always use the cream or ointment as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.

Side effects of Provate Plus Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Provate Plus
  • Reduction in bone density
  • Upset stomach

How to use Provate Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Provate Plus Cream works

PROVATE PLUS CREAM is a steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.

Quick tips

  • PROVATE PLUS CREAM is used to treat the redness, swelling, itching, and discomfort of various skin conditions.
  • It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.
  • Don't use it more often or for longer than advised by your doctor.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become infected you should stop using PROVATE PLUS CREAM and consult your doctor.
  • Consult your doctor if your skin condition has not improved after 2 weeks of treatment. 

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
PROVATE PLUS CREAM is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
PROVATE PLUS CREAM may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Provate Plus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Etanercept (Injection Route)

Your doctor may monitor you for development of signs and symptoms of infection during treatment.

Frequently asked questions

PROVATE PLUS CREAM belongs to a group of medicines called steroids, also known as corticosteroids. PROVATE PLUS CREAM is used to treat various allergic skin conditions (e.g., eczema, dermatitis, allergies, rash). PROVATE PLUS CREAM effectively reduces symptoms such as swelling, itching and redness associated with such conditions.
No, PROVATE PLUS CREAM should never be applied in those areas of the skin that have burns, cuts or scrapes. If PROVATE PLUS CREAM accidently gets onto such areas, rinse the area thoroughly with water. It is advisable that you use this medicine only as directed by your doctor to avoid any adverse effects and worsening of your condition.
PROVATE PLUS CREAM works by decreasing the inflammation caused by allergies. It reduces inflammation by blocking the release of certain natural substances that cause allergic symptoms such as swelling, redness and pain.
The time required by PROVATE PLUS CREAM to start showing its effects may differ from person to person. Usually, it starts showing relief within 8 hours of starting PROVATE PLUS CREAM. It may even take several days before you see maximum benefits. In order to improve your symptoms faster, it is important to take the medicine regularly to gain maximum benefit from the medicine.
Before using PROVATE PLUS CREAM, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If PROVATE PLUS CREAM gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.
Be careful not to get PROVATE PLUS CREAM into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use PROVATE PLUS CREAM if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with PROVATE PLUS CREAM with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Also, let your doctor know if you are planning to conceive. Pregnant and breastfeeding mothers should use PROVATE PLUS CREAM only if prescribed by the doctor.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Glucocorticoids

References

  1. Boushey HA. Drugs Used in Asthma. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 348.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 125-26.
  3. Betamethasone. Uxbridge, Middlesex: Glaxo Wellcome UK Ltd.; 1997 [revised 7 Sep. 2017]. [Accessed 04 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Percos India Pvt Ltd
Address: Plot No. 5, Basement Neelkanth Chambers - 1, L.S.C. Saini Enclave, New Delhi - 110092, India

Vendor Details

Country of origin: India
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