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Propyderm Cream

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 24 Nov 2025 | 02:46 PM (IST)
Propyderm Cream is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has antimicrobial action against infection-causing microorganisms.
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General Information

Contains

Betamethasone (NA)+ Gentamicin (NA)+ Miconazole (NA)

Marketer

Hegde and Hegde Pharmaceutica LLP

Storage

Store below 30°C
The content is shown in English
Propyderm Cream image
Propyderm Cream image

Product introduction

Propyderm Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.

The most common side effect of this medicine includes itching, dryness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine. You should consult the doctor about prescribing an alternative medicine for your condition.

Uses of Propyderm Cream

Benefits of Propyderm Cream

Treatment of Skin infections
Propyderm Cream is a combination of medicines used to treat skin infections caused by microorganisms such as bacteria and fungi. It works by killing and stopping the growth of infection causing microorganisms, thereby clearing the infection and relieving the symptoms. It also blocks the release of chemicals that cause symptoms such as itching, redness and swelling. Therefore this medicine relieves the inflammation due to these infections.

You should use this medicine for as long as it is prescribed, even if your symptoms disappear, otherwise they may come back. Depending on the type of infection you are treating, this may be several weeks. Even after your infection is completely cured, you may have to apply it occasionally to prevent the symptoms from returning.

Side effects of Propyderm Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Propyderm
  • Application site reactions (burning, irritation, itching and redness)
  • Thinning of skin
  • Skin peeling

How to use Propyderm Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Propyderm Cream works

Propyderm Cream is a combination of three medicines: Betamethasone, Gentamicin and Miconazole, which treats skin infections. Betamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Gentamicin is an antibiotic which stops the growth of bacteria while Miconazole is an antifungal which stops the growth of fungi on the skin. Together, they treat your skin infection effectively.

Quick tips

  • Propyderm Cream helps treat skin infections.
  • It is for use on skin only. Do not use it in your eyes, mouth, or vagina. Rinse with cold water if you accidentally get it in these areas.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become more irritated, you should stop using Propyderm Cream and consult your doctor.
  • Don't use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not improve after 1 week of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Propyderm Cream is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Propyderm Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

No, do not stop taking Propyderm Cream and finish the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cleared.
Usually, Propyderm Cream starts working soon after applying it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Propyderm Cream should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of this medicine to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using it, unless it is used for treating infection of the hands.
No, do not stop using Propyderm Cream and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Do not use Propyderm Cream for longer than the prescribed period of time, especially on the face as it may cause thinning of the skin. If it has to be applied over the eyelid, make sure it does not get into your eyes. Unless told by your doctor, do not apply a bandage or dressing to the area being treated, as this will increase absorption of the preparation and increase the risk of side-effects. This medicine should only be used by the patient and never be given to other people even if their condition appears to be the same.
The dosage and duration of using Propyderm Cream should be strictly according to the doctor’s advice. This medicine when used in higher doses and for longer periods can get absorbed in the blood and cause adrenal suppression and Cushing's syndrome. It can cause weight gain, high blood pressure and rounding of the face. Its application can cause a change in color of skin at the site of application. Veins beneath the skin become visible due to the thinning and weakening of the skin. There could be an increased hair growth. If you experience an increased severity of your symptoms, please consult your doctor for re-evaluation.
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Keep it away from pets and children.
Use of Propyderm Cream is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. Avoid its use for treatment of any viral infections (herpes or chickenpox) or for treatment of acne or rosacea. Avoid its use in itchy areas which are not red and around the genitalia and anus. Consult your doctor before using it for any condition.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA

References

  1. Betamethasone. Uxbridge, Middlesex: Glaxo Wellcome UK Ltd.; 1997 [revised 7 Sep. 2017]. [Accessed 04 Apr. 2019] (online) Available from:
  2. ScienceDirect. Gentamicin. [Accessed 31 Mar. 2019] (online) Available from:
  3. Miconazole. Schorndorf, Germany: Catalent Germany Schorndorf; 1974 [revised Aug. 2018]. [Accessed 29 Mar. 2019] (online) Available from:
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User feedback

Once A Day
52%
Twice A Day
40%
Thrice A Day
5%
Four Times A Day
2%
Fungal infections
50%
Skin infections
50%
Poor
100%
No Side Effect
100%
Empty stomach
100%
Not Expensive
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hegde and Hegde Pharmaceutica LLP
Address: 301. Om Chambers, 123 August Kranti Marg Kemps Corner, Mumbai-400034

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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