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Propess Pessaries

Dinoprostone (10mg)
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Propess Pessaries is a medicine used to induce labor in women, who are ready to deliver a full term baby. It works by softening and widening the cervix (lower end of the uterus) and helps the baby to pass through easily.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Apr 2026 | 03:24 PM (IST)
₹2480 MRP ₹2707.038% off 
 
 
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General Information

The content is shown in English
Propess Pessaries image
Propess Pessaries image

Product introduction

Propess Pessaries is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals. The dose and how often you take it depends on what you are taking it for. You might be asked to lie down for at least 30 minutes after medicine application.

The most common side effects of this medicine include vomiting, diarrhea, back pain, and flushing of the skin.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a heart attack, or have asthma or have high or low blood pressure. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You may be checked for contraction timely by your doctor while on treatment with this medicine.

Uses of Propess Pessaries

Benefits of Propess Pessaries

Induction of labour
Labour induction is a medical process used to start childbirth when it doesn’t begin naturally and early delivery is considered safer for the mother or baby. Propess Pessaries helps soften and open the cervix, making it easier for labour to progress and increasing the chances of a smooth delivery.

Side effects of Propess Pessaries

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Propess
  • Vomiting
  • Fever
  • Uterine tachysystole
  • Uterine hyperstimulation
  • Nausea
  • Diarrhea
  • Flushing of skin

How to use Propess Pessaries

Take this medicine in the dose and duration as advised by your doctor. Wash and dry your vaginal area. Lie on your back and gently insert the pessary into the vagina as high as possible with or without the use of an applicator as mentioned in the label.

How Propess Pessaries works

Propess Pessaries is similar to a natural substance (E2 prostaglandin) which is released in your body when labour starts. It works by opening the part of the birth canal (cervix) and causing the uterus to contract, to allow the baby through.

Quick tips

  • Propess Pessaries helps induce labour in pregnant women.
  •  It is only used in a hospital or clinic by your doctor.
  • Your doctor may ask you to lie down for at least 30 minutes to keep the medication in place.
  • A second dose of medicine may be given if contractions are not strong enough.
  • You may be monitored closely after administration  to make sure that the contractions do not become too strong and no distress comes to the baby.
  • Inform your doctor if you have heart, kidney, lung or liver disease or if you have a history of asthma.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Propess Pessaries during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Propess Pessaries during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Propess Pessaries works similar to Prostaglandin E2, a substance produced naturally by the women’s body. It helps in initiating the labor in women who are ready to deliver a full-term baby. It works by softening and widening the cervix.
This medicine is not for self-application purpose. It is usually applied in hospital settings by a medical healthcare professional like a nurse or doctor. It is placed in the upper vagina. This medicine remains active for 6 hours.
The dose would depend on your response to the medicine. In some patients, a single dose of this medicine usually starts labor. Sometimes, a dose may be repeated if your doctor feels that the cervix is not completely ready for the labor. In a few cases, the dose may be repeated multiple times.
After inserting this medicine, you and your’s baby vitals may be monitored constantly. You will be advised to lie down for at least 30 minutes. Any contractions will also be monitored. Your doctor may examine you after 6 hours or earlier in case you have strong contractions, to check for progress of labor.
The side effects of Propess Pessaries are uncommon but they can occur. A small number of women may have fever, nausea, vomiting, or diarrhea. Some women may experience a high number of uterine contractions, which may or may not stress your baby.

Fact Box

Chemical Class

Prostaglandin derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Prostaglandin E2 (PGE2) Analogues

References

  1. Schimmer BP, Parker KL. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1850.
  2. Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 325.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 413-14.
  4. Dinoprostone. New York, New York: Pfizer; 2017. [Accessed 03 Apr. 2019] (online) Available from:
  5. Dinoprostone. East Kilbride, Scotland: Ferring Controlled Therapeutics Ltd. (FCT); 2017. [Accessed 14 Feb. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
  7. Dinoprostone. New York, NY: Pharmacia and Upjohn Company LLC.; 2025. [Accessed 22 Apr. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA

Vendor Details

Country of origin: India
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