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Prokoff Syrup

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 01 Feb 2026 | 04:48 PM (IST)
Prokoff Syrup is a combination medicine used in the treatment of dry cough. It relieves allergy symptoms such as runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness.
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General Information

Contains

Phenylpropanolamine (12.5mg)+ Chlorpheniramine Maleate (2mg)+ Dextromethorphan Hydrobromide (10mg)

Marketer

SPS Medipol Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Prokoff Syrup image
Prokoff Syrup image

Product introduction

Prokoff Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, upset stomach, insomnia, palpitations, and high blood pressure. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Never support self-medication or recommend your medicine to another person. Keep it out of reach of children. It is beneficial to have plenty of fluids while taking this medication. Before taking it, you should tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. Pregnant or breastfeeding women should consult their doctor before taking this medicine.

Uses of Prokoff Syrup

Benefits of Prokoff Syrup

Dry cough
A dry cough is a cough where no phlegm or mucus is produced. It may cause a tickling sensation or itching in the throat and may be due to cold, flu, allergies or throat irritants. Prokoff Syrup suppresses severe dry cough and gives you relief from an itchy throat. Apart from this, it also reduces symptoms of allergy like watery eyes, sneezing and runny nose. Along with taking Prokoff Syrup, gargling with warm salt water and having ginger or honey can help you manage dry cough.

Side effects of Prokoff Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prokoff
  • Nausea
  • Upset stomach
  • Insomnia (difficulty in sleeping)
  • Palpitations
  • Sleepiness
  • High blood pressure

How to use Prokoff Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Prokoff Syrup may be taken with or without food.

How Prokoff Syrup works

Prokoff Syrup is a combination of three medicines: Phenylpropanolamine, Chlorpheniramine Maleate and Dextromethorphan Hydrobromide which relieve dry cough. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain.

Quick tips

  • Prokoff Syrup is prescribed to get relief from a dry cough.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
  • Consult your doctor if you do not see any improvement and have a cough for more than 7 days.
  • Let your doctor know if you are taking any anti-depressants.
  • Inform your doctor if you have had a cough for a long time or if you have asthma or suffer from serious asthma attacks, or if your cough is accompanied by a fever, rash, or persistent headache.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Prokoff Syrup.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Prokoff Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Prokoff Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Prokoff Syrup may cause side effects that could affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Prokoff Syrup is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

UNSAFE
Prokoff Syrup is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Prokoff Syrup is used to treat the symptoms of the common cold and flu. It provides relief from a range of symptoms, including fever, headache, body aches, stuffy nose, runny nose, sneezing, and watery eyes.<br>
Yes, one of the main ingredients in Prokoff Syrup, chlorpheniramine maleate, can cause significant drowsiness and sleepiness. Because of this, it is often best to take this medicine when you are able to rest, and you should avoid activities that require full mental alertness, like driving or operating heavy machinery.<br>
You should start to feel relief from symptoms like fever, pain, and nasal congestion within about 30 to 60 minutes of taking Prokoff Syrup. The full effects will be felt within a couple of hours as the medicine is absorbed into your bloodstream.<br>
The antihistamine (chlorpheniramine) and decongestant (phenylpropanolamine) in Prokoff Syrup make it effective for treating allergic rhinitis (hay fever). It can help relieve sneezing, a runny nose, and a stuffy nose associated with seasonal allergies.<br>
Before starting Prokoff Syrup, you should inform your doctor if you have a history of high blood pressure, heart disease, thyroid problems, glaucoma, or an enlarged prostate. The phenylpropanolamine in this medicine can make these conditions worse, so your doctor will need to determine if it is safe for you.<br>
Prokoff Syrup is intended for short‑term relief of symptoms. You should not take it for more than 5 to 7 days. If your symptoms persist or get worse, you should stop taking the medicine and consult your doctor.<br>

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

References

  1. MedInida. Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, Phenylpropanolamine HCL. [Accessed 18 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: SPS Medipol Pvt Ltd
Address: Plot No. 60, Sector-28, DLF Golf Course Road, Gurgaon,Haryana-122001

Vendor Details

Country of origin: India

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