Prilido Cream

Prilocaine (2.5% w/w)+ Lidocaine (2.5% w/w)

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Prescription

required

Prilido Cream is a combination of two local anesthetic medicines, that helps to numb the area where it is applied. It is used on normal or unbroken skin to prevent pain before certain procedures like inserting a needle, suturing of a wound etc.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 28 Jan 2026 | 11:56 AM (IST)

₹86.1 MRP ₹95.6310% off

Gurgaon

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General Information

Contains

Prilocaine (2.5% w/w)+ Lidocaine (2.5% w/w)

Marketer

Ethinext Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Prilido Cream works by temporarily numbing the skin and surrounding area. It should be used in the dose and duration as advised by your doctor. This medicine is for external use only. Make sure that the affected area is clean and dry before applying this medicine. Apply a thin layer and rub it gently to form a layer of about 2-3mm. After that, apply an occlusive dressing to protect the area. Keep the dressing for a minimum of 2 hours before any scheduled treatment or surgery. Avoid getting it into your eyes or mouth. If accidental exposure occurs, rinse thoroughly with water.

The most common side effects of this medicine include application site reactions like a burning sensation, irritation, itching, redness, and rashes. However, these are usually temporary and resolve on their own. Please consult your doctor if these do not go away or bother you for a longer duration.

Uses of Prilido Cream

Local anesthesia (Numb tissues in a specific area)

Benefits of Prilido Cream

Local anesthesia (Numb tissues in a specific area)
Prilido Cream is an anesthetic and causes loss of feeling (numbness) of skin on the area of injection. This reduces pain and discomfort. Prilido Cream is given by doctor or nurse during surgery and other medical and dental procedures. It works by blocking nerve signals in the brain and thus reduces pain sensation.

Side effects of Prilido Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prilido

Application site reactions (burning, irritation, itching and redness)
Rash

How to use Prilido Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Prilido Cream works

Prilido Cream is a combination of two medicines: Prilocaine and Lidocaine. It works by blocking pain signals from the nerves of the affected area to t he brain. This decreases the sensation of pain.

All substitutes for Prilido Cream

For information purposes only. Consult a doctor before taking any medicine.

Numbex Cream

by Salve Pharmaceuticals Pvt Ltd

₹15.64/gm of cream

9% cheaper

Numbex Cream

by Salve Pharmaceuticals Pvt Ltd

₹18.97/gm of cream

10% costlier

Quick tips

Prilido Cream must be applied over intact skin and cover with treated area with dressing.
Wash your hands properly with soap before and after applying the medicine.
Avoid contact with the eyes, mouth, nose or any mucous membrane and rinse thoroughly in case of accidental contact or seek medical help in case of ingestion.
It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.

Safety advice

Alcohol

No interaction found/established

Pregnancy

SAFE IF PRESCRIBED

Prilido Cream is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Prilido Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What is Prilido Cream used for?

Prilido Cream is a combination of two local anesthetics, prilocaine and lidocaine. It is used to numb the surface of the intact skin before needle insertion or minor superficial surgical procedures. In addition, when applied to genital mucosa (inner membrane of private parts) it provides numbness, thereby preventing any pain while instilling the injection.

How long does Prilido Cream last for?

The effect of numbness after application of Prilido Cream is expected to be upto 3 hours under pressure dressing and may persist for 1 to 2 hours after removal of the cream.

How do you use Prilido Cream?

Prilido Cream should be applied to the skin for at least 1 hour before the start of a routine procedure (needle insertion). Maintain a gap of at least 2 hours before the start of a painful procedure (minor surgical procedure). Apply pressure bandage on the top to give an even distribution of cream and protect the area. When applied to the genital mucosa, a thick layer of Prilido Cream is applied to the skin surface for 15 minutes, before giving local anesthetic injection. Your doctor will advise the exact duration to apply the cream.

Can Prilido Cream be used on open wounds?

No, Prilido Cream must used on unbroken skin and the genital area. Do not apply to open wounds or broken skin unless directed by your doctor.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

User feedback

Patients taking Prilido Cream

Once A Day

80%

Twice A Day

20%

What are you using Prilido Cream for?

Local anesthesia (Numb tissues in a specific area)

67%

Others

33%

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Prilido Cream?

No Side Effect

100%

How do you take Prilido Cream?

With or without food

100%

Please rate Prilido Cream on price

Average

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ethinext Pharma
Address: B-407 – Imperial Heights, Opp. Big Bazzar, 150ft Ring Road, Rajkot – 360005 (Gujarat, India) / Plot No. 19, 20 Jay Jalaram Industries Estate-1,Godown No. 2&3, Shed No. 2A, 2B, 3A & 3B,R. Sur. No.: 79/5, Sokhada, Rajkot - 360003, Gujarat, India / Hi Tech Ind. Sokhda Gam, Plot No. 19/20/21, New 150ft Ring Road, Nr. Bansal Chokdi, Sokhda-363670, Gujarat, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Prilido Cream

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Prilido Cream

Benefits of Prilido Cream

Side effects of Prilido Cream

How to use Prilido Cream

How Prilido Cream works

All substitutes for Prilido Cream

Numbex Cream

Numbex Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Prilido Cream used for?

How long does Prilido Cream last for?

How do you use Prilido Cream?

Can Prilido Cream be used on open wounds?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Prilido Cream

What are you using Prilido Cream for?

How much was the improvement?

What were the side-effects while using Prilido Cream?

How do you take Prilido Cream?

Please rate Prilido Cream on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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