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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Ppbest 10 mg/20 mg Tablet


Overview

Introduction

Ppbest 10 mg/20 mg Tablet is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.

Ppbest 10 mg/20 mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are diarrhea, stomach pain, dryness in mouth, headache, flatulence, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney or liver disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Side effects of Ppbest Tablet

Common
  • Diarrhea
  • Stomach pain
  • Dryness in mouth
  • Headache
  • Dizziness
  • Flatulence
  • Weakness
  • Flu-like symptoms
  • Flu-like symptoms

How to use Ppbest Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ppbest 10 mg/20 mg Tablet is to be taken empty stomach.

How Ppbest Tablet works

Ppbest 10 mg/20 mg Tablet is a combination of two medicines: Domperidone and Rabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Ppbest 10 mg/20 mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Ppbest 10 mg/20 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Ppbest 10 mg/20 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Ppbest 10 mg/20 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Ppbest 10 mg/20 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ppbest 10 mg/20 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Ppbest 10 mg/20 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Ppbest 10 mg/20 mg Tablet may be needed. Please consult your doctor.
Use of Ppbest 10 mg/20 mg Tablet is not recommended in patients with moderate and severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • You have been prescribed Ppbest 10 mg/20 mg Tablet for the treatment of acidity and heartburn.
  • Take it one hour before the meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Patient Concerns

arrow
Gastric nausea vomiting reflux
Dr. Pushkar Mani
Physician
sompraz D 40 mg twice daily 1 hour before meal for 10 days
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
arrow
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User Feedback


FAQs

Q. What are the contraindications of Ppbest?

The use of Ppbest is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.

Q. Can the use of Ppbest cause dry mouth?

Yes, the use of Ppbest can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.

Q. Can the use of Ppbest cause diarrhea?

Yes, the use of Ppbest can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.

Q. What is the recommended storage condition for Ppbest?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Ppbest?

Ppbest is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.

Q. Is it safe to use Ppbest?

Yes, Ppbest is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.

Q. What is the best time to take Ppbest?

It is best to take Ppbest before the first meal of the day or on an empty stomach.

Q. Can the use of Ppbest cause abnormal heartbeat?

Yes, the use of Ppbest can increase the risk of developing irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. Rabeprazole. Charlotte, North Carolina: FSC Laboratories; 1999 [revised Dec. 2014]. [Accessed on 28 Mar. 2019] (online) Available from:External Link
  3. International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. Rabeprazole sodium. Barnstaple, Devon: Accord Healthcare Limited; 14 Jul. 2010 [revised 27 Apr. 2018]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  5. Domperidone/domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2017. [Accessed 12 Apr. 2019] (online) Available from:External Link
  6. Rabeprazole sodium. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 05 Jan. 2018]. [Accessed 12 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Vidakem Lifesicence Pvt Ltd, "PARAS",7-Vidyanagar Society,Part-III, Opp.Vidyanagar School, Usmanpura, Ahmedabad-Gujarat, India,
A licensed vendor partner from your nearest location will deliver Ppbest 10 mg/20 mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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