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Polyclav ES Syrup is an antibiotic that helps your body fight infections caused by bacteria. It is used to treat infections of the lungs (e.g., pneumonia), the ear, the nasal sinus, the urinary tract, the skin, and the soft tissue. It will not work for viral infections such as the common cold.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Mar 2026 | 01:39 PM (IST)
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Polyclav ES Syrup image
Polyclav ES Syrup image
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Polyclav ES Syrup image
Polyclav ES Syrup image
Polyclav ES Syrup image
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Polyclav ES Syrup image

Product introduction

Polyclav ES Syrup is best taken with a meal to reduce the chance of a stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time daily will help you remember to take it. The dose will depend on what you are being treated for, but you should always complete an entire course of this antibiotic as your doctor prescribes. Please do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive, and the infection may return or worsen.


The most common side effects of Polyclav ES Syrup include recurrent or persistent fungal infection (mucocutaneous candidiasis), nausea, diarrhea, and vomiting. If you experience any side effects that are persistent or worsen, consult your doctor for guidance.


Before taking it, let your doctor know if you are allergic to any antibiotics or have kidney or liver problems. You should also inform your doctor about all other medicines you are taking, as they may affect or be affected by Polyclav ES Syrup. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe.

Uses of Polyclav ES Syrup

Benefits of Polyclav ES Syrup

Treatment of Bacterial infections
Polyclav ES Syrup is a medicine that is used to treat bacterial infections. It can treat many bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to ensure all bacteria are killed and do not become resistant.

Side effects of Polyclav ES Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Polyclav ES
  • Mucocutaneous candidiasis
  • Diarrhea
  • Nausea
  • Vomiting

How to use Polyclav ES Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Polyclav ES Syrup should be taken with or after food.

How Polyclav ES Syrup works

Polyclav ES Syrup is a combination of two medicines: Amoxycillin and Clavulanic Acid. Amoxycillin is an antibiotic. It works by preventing the formation of the bacterial protective covering, which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor that reduces resistance and enhances the activity of Amoxycillin against bacteria.

Quick tips

  • Diarrhea may occur as a side effect. Taking probiotics along with Polyclav ES Syrup may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Do not take antacids 2 hours before or after taking Polyclav ES Syrup.
  • Stop taking Polyclav ES Syrup and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking it.
  • Do not use leftover medicine to treat any infection in the future. Always consult your doctor before taking any antibiotic.
  • Stick to simple meals, avoid rich or spicy food and drink plenty of water while taking Polyclav ES Syrup.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Polyclav ES Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Polyclav ES Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Polyclav ES Syrup should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Polyclav ES Syrup may cause side effects that could affect your ability to drive.
Polyclav ES Syrup may cause side effects such as allergic reactions, dizziness, or fits that may make you unfit to drive.
Kidney

Kidney

CAUTION
Polyclav ES Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of this medicine is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Polyclav ES Syrup should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is recommended while you are taking this medicine

Frequently asked questions

Polyclav ES Syrup is a combination of two medicines (amoxycillin and clavulanic acid) used to treat bacterial infections, such as tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection, and oral cavity infections. The medicine works by killing the harmful bacteria that cause infections.
Polyclav ES Syrup is safe to use when taken as advised by the doctor. However, in some patients, it may cause common side effects like diarrhea, nausea, vomiting, rash, allergic reaction, and other uncommon or rare side effects. If you experience any persistent problem during your treatment, inform your doctor as soon as possible.
The use of Polyclav ES Syrup is considered harmful for patients with known allergy to penicillins or any other ingredient of the medicine. It should not be used in patients with a history of liver disease.
Yes, the use of Polyclav ES Syrup can lower the efficacy of birth control pills. Consult your doctor and seek advice regarding the use of other methods of contraception (e.g., condom, diaphragm, spermicide) while you are taking Polyclav ES Syrup.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose off the unused medicine. Make sure it is not consumed by pets, children, and other people.
No, do not stop taking Polyclav ES Syrup before completing the full course of the treatment, even if you feel better. Your symptoms may improve before the infection is completely cured. Hence, continue taking the medicine for the due course as the medicine may still be showing beneficial effects.
Yes, Polyclav ES Syrup can cause an allergic reaction. It is considered to be harmful for patients with known allergies to penicillins. Get emergency medical help if you have any signs of an allergic reaction, like hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.
Yes, the use of Polyclav ES Syrup can cause diarrhea. It is an antibiotic that kills the harmful bacteria. Additionally, it may affect the helpful bacteria in your stomach or intestine as well and cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequent urination with dark colored and strong-smelling urine. Do not take any other medicine without consulting a doctor.
No, Polyclav ES Syrup does not treat a viral infection like the common cold or flu. Consult your doctor and avoid self-medication.

Fact Box

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Therapeutic Class

ANTI INFECTIVES
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Polyclav ES Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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