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Polivy 30mg Injection

Polatuzumab (30mg)
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Polivy 30mg Injection is a medicine used in combination with other medicines to treat a certain type of non-Hodgkin's lymphoma (NHL). Polivy 30mg Injection belongs to a class of medications called antibody-drug conjugates. It works by killing cancer cells.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)
₹189113 MRP ₹22222515% off 
 
 
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Polivy 30mg Injection image
Polivy 30mg Injection image

Product introduction

Polivy 30mg Injection is administered as an injection under the supervision of a doctor or a nurse. Get the injection in the exact dose and duration advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. Do not stop getting the injection unless your doctor tells you to.


The most common side effects of this medicine include peripheral neuropathy, nausea, fatigue, diarrhea, constipation, and hair loss. If any of these side effects persist or get worse, let your doctor know. They may be able to help by adjusting the dose or suggest ways to treat the symptoms. While on treatment with this medicine, your doctor may advise regular blood tests.


Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Polivy Injection

Benefits of Polivy Injection

Treatment of Non-Hodgkin lymphoma (NHL)
Non-Hodgkin lymphoma (NHL) is a type of cancer that originates in the lymphatic system, affecting white blood cells known as lymphocytes. White blood cells are those cells that help us to fight infections. Polivy 30mg Injection targets the cancer cells causing the cancer cells to die or stop growing. This way it prevents their further growth. This medicine also lowers immune response and helps to reduce pain and inflammation.

Side effects of Polivy Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Polivy
  • Decreased white blood cell count (neutrophils)
  • Increased uric acid level in blood
  • Anemia (low number of red blood cells)
  • Low blood platelets
  • Fever
  • Decreased appetite
  • Pneumonia
  • Hair loss
  • Mucositis
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Nausea
  • Fatigue
  • Diarrhea
  • Constipation
  • Lymphopenia

How to use Polivy Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Polivy Injection works

Polivy 30mg Injection works by binding with cancer cells and releasing a chemical called monomethyl auristatin E, into the cell causing the cancer cells to die or stop growing.

Quick tips

  • Polivy 30mg Injection must be given through a vein by a doctor in a hospital setting only.
  • You might be given other medicines before Polivy 30mg Injection to help prevent allergic or infusion-related reactions.
  • Tell your doctor immediately if you feel feverish, have breathing issues, or notice a skin rash during or after the infusion.
  • Avoid live vaccines while on Polivy 30mg Injection treatment, as your body’s ability to fight infections may be lowered.
  • You will need regular blood tests during treatment to check white blood cells and liver health.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Polivy 30mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Polivy 30mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Polivy 30mg Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Polivy 30mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Polivy 30mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Polivy 30mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Polivy 30mg Injection is a targeted cancer medication (antibody-drug conjugate) specifically used to treat diffuse large B-cell lymphoma (DLBCL), an aggressive form of blood cancer. It is typically administered in combination with other cancer drugs for patients who have not responded to previous treatments, for recurring lymphoma, or as part of specific treatment protocols for certain lymphoma types.
Polivy 30mg Injection is administered through intravenous (IV) infusion at a hospital or cancer treatment center. The medication is slowly injected into a vein in your arm or through a port. Treatment cycles typically occur every 21 days for a total of 6 cycles. The initial infusion lasts approximately 90 minutes, while subsequent infusions may be shorter if you tolerate the treatment well.
During Polivy 30mg Injection treatment, your doctor will conduct regular blood tests to monitor your cell counts and liver function. They will watch for signs of infection, assess any nerve-related symptoms, and perform periodic imaging scans to evaluate how well the treatment is working against your lymphoma.
During Polivy 30mg Injection treatment, you should avoid crowded places and people who are sick, practice frequent hand washing, immediately report any signs of infection to your doctor, take care to prevent cuts and injuries, and strictly follow all medication instructions provided by your doctor.
Seek immediate medical attention if you develop severe side effects of Polivy 30mg Injection such as fever or chills, experience unusual bleeding or bruising, feel extreme fatigue, notice numbness or tingling in your hands or feet, have difficulty breathing, or suffer from persistent nausea and vomiting.
The duration of your Polivy 30mg Injection treatment depends on multiple factors including how your cancer responds to the medication, any side effects you experience, the specific characteristics and stage of your lymphoma, and your overall treatment strategy. Your oncologist will regularly assess your progress and adjust the treatment plan accordingly.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Vendor Details

Country of origin: India
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