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Plugpen XP Injection

Meropenem (1000mg)+ Sulbactam (500mg)

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Plugpen XP Injection is a combination medicine that is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 Apr 2026 | 09:17 PM (IST)

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General Information

Contains

Meropenem (1000mg)+ Sulbactam (500mg)

Marketer

Samarth Life Sciences Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Plugpen XP Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better.

The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. You may also experience injection site redness, swelling, and pain that goes away with time. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of Plugpen XP Injection

Severe bacterial infections

Benefits of Plugpen XP Injection

Severe bacterial infections
Plugpen XP Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of lungs (pneumonia) and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Plugpen XP Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Plugpen XP Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Plugpen XP

Nausea
Vomiting
Diarrhea
Headache
Rash

How to use Plugpen XP Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Plugpen XP Injection works

Plugpen XP Injection is a combination of two medicines: Meropenem and Sulbactam. Meropenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Sulbactam is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate Meropenem. Addition of Sulbactam reduces resistance and enhances the activity of Meropenem against bacteria.

All substitutes for Plugpen XP Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Plugpen XP Injection is given as an injection under the supervision of a doctor only.
Do not skip any doses and finish the full course of treatment even if you feel better.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how medicine affects you.
It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
Discontinue Plugpen XP Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Plugpen XP Injection.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Plugpen XP Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Plugpen XP Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Plugpen XP Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Plugpen XP Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Plugpen XP Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Plugpen XP Injection used for?

Plugpen XP Injection is a potent antibiotic used to treat serious bacterial infections, such as pneumonia, urinary tract infections, abdominal infections, skin infections, meningitis, blood infections, and infections in patients with weakened immune systems. Meropenem in Plugpen XP Injection kills a wide range of bacteria, while sulbactam in Plugpen XP Injection helps prevent some bacteria from resisting the antibiotic.

Who should not use Plugpen XP Injection?

Individuals should not use Plugpen XP Injection if they are allergic to meropenem, sulbactam, or any other carbapenem, beta-lactam, or cephalosporin antibiotics. If you have a history of severe allergic reactions to these types of antibiotics, inform your doctor before starting treatment.

Can Plugpen XP Injection cause serious side effects?

Though Plugpen XP Injection is generally well tolerated, serious side effects include allergic reactions, severe skin rashes, seizures (especially in patients with brain disorders or kidney problems), and severe or persistent diarrhea. Seek immediate medical attention if you experience any of these symptoms.

Will I need to be monitored during Plugpen XP Injection treatment?

Yes, your doctor may regularly assess kidney, liver, and blood functions during prolonged Plugpen XP Injection treatment. Your doctor may also advise performing lab tests to ensure the infection is responding to the antibiotic.

How long will the Plugpen XP Injection treatment last, and can the infection become resistant?

The duration of Plugpen XP Injection depends on the infection type and severity. Prolonged or inappropriate use of this medicine may increase the risk of resistance. Follow your doctor’s instructions, and complete the full course, even if symptoms improve.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Plugpen XP Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Plugpen XP Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Plugpen XP Injection

Benefits of Plugpen XP Injection

Side effects of Plugpen XP Injection

How to use Plugpen XP Injection

How Plugpen XP Injection works

All substitutes for Plugpen XP Injection

Meromac Plus 1000mg/500mg Injection

Merotrol S 1000mg/500mg Injection

Merotec XP 1.5G Injection

Germero SB 1.5gm Injection

Meroplan-S Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Plugpen XP Injection used for?

Who should not use Plugpen XP Injection?

Can Plugpen XP Injection cause serious side effects?

Will I need to be monitored during Plugpen XP Injection treatment?

How long will the Plugpen XP Injection treatment last, and can the infection become resistant?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests